anti-Surfactant Associated Protein B (SFTPB) Antibodies

SFTPB encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Additionally we are shipping SFTPB Kits (60) and SFTPB Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SFTPB 6439 P07988
SFTPB 20388 P50405
SFTPB 192155 P22355
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-SFTPB Antibodies at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-SFTPB Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  721_B cell lysate Host:  Mouse  Target Name:  SFTPB  Sample Tissue:  Mouse Liver  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of Surfactant Protein B expression in HepG2 (A), Y79 (B), A549 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Mouse Liver Tissue. Figure. Western Blot; Sample: Recombinant SPB, Mouse. 100 μg Log in to see 15 to 18 Days
$342.00
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Rat Lung Tissue. 100 μg Log in to see 13 to 16 Days
$362.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$181.73
Details
Dog Rabbit Un-conjugated IHC, IHC (p), WB 50 μg Log in to see 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis SP-B using LOVO whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis using SFTPB Antibody (Center) Cat.-No AP53885PU-N in HepG2 cell line lysates (35ug/lane). This demonstrates the SFTPB antibody detected the SFTPB protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB SFTPB Antibody (Center)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SFTPB antibody detected the SFTPB protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded lung tissue 100 μg Log in to see 13 to 16 Days
$332.00
Details

Top referenced anti-SFTPB Antibodies

  1. Human Polyclonal SFTPB Primary Antibody for IHC (p), IHC - ABIN269321 : Guo, Kazadaeva, Ortega, Manjunath, Desai: Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. in Developmental biology 2017 (PubMed)

  2. Human Polyclonal SFTPB Primary Antibody for IHC, WB - ABIN4891754 : Mayor, Finch, Zehr, Morselli, Neinast, Frank, Hahner, Wang, Rakheja, Palmer, Rosenfeld, Savani, Clegg: Maternal high-fat diet is associated with impaired fetal lung development. in American journal of physiology. Lung cellular and molecular physiology 2015 (PubMed)

More Antibodies against SFTPB Interaction Partners

Human Surfactant Associated Protein B (SFTPB) interaction partners

  1. TGF beta (show TGFB1 Antibodies) markedly decreased expression of SP-A, SP-B, SP-C (show SFTPC Antibodies), fatty acid synthase (show FASN Antibodies), and the phospholipid transporter ABCA3 (show ABCA3 Antibodies). However, TGF beta (show TGFB1 Antibodies) increased protein levels of SP-D (show SFTPD Antibodies) with little change in mRNA levels.

  2. Surfactant protein B suppresses lung cancer progression by inhibiting secretory phospholipase A2 (show YWHAZ Antibodies) activity and arachidonic acid production.

  3. SP-A (+186A/G) and SP-B (1580C/T) polymorphisms are strongly associated with the risk of respiratory distress syndrome (RDS (show PRPH2 Antibodies)) in preterm infants. Notably, reduced serum SP-A levels were correlated with a high risk of RDS (show PRPH2 Antibodies) and may serve as novel biomarkers for RDS (show PRPH2 Antibodies) detection and monitoring.

  4. Differences were found regarding SPA and pro-SPB expression in the vast majority of subjects: in some lungs, SPA was more expressed whereas in others pro-SPB showed an higher degree of immunoreactivity. The expression of both surfactant proteins was not strictly correlated with gestational age.

  5. There is no significant association between the gene polymorphism of the R236C site in exon 7 of SP-B gene and the incidence ofneonatal respiratory distress syndrome (NRDS) in Han populations in that region.

  6. Rare mutations in surfactant-associated genes contribute to neonatal respiratory distress syndrome. The frequency of mutations in these genes in the Chinese population is unknown. We resequenced all exons of the surfactant protein-B (SFTPB) and we did not find any rare mutations in SFTPB

  7. mice with SP-B-C allele are more susceptible to S. aureus pneumonia than mice with SP-B-T allele, and that CMC2.24 attenuates lung injury thus reducing mortality.

  8. In term newborns with pneumonia, SP-B increases with respect to total phospholipids, and disaturated-phosphatidylcholine (show SGMS2 Antibodies) and is turned over at a faster rate.

  9. SP-B -18C/A and 1580C/T polymorphisms are associated with bronchopulmonary dysplasia

  10. These results demonstrate for the first time that human SP-B C allele is more susceptible to bacterial pneumonia than SP-B T allele in vivo.

Mouse (Murine) Surfactant Associated Protein B (SFTPB) interaction partners

  1. In triple KO mice, the HO-induced lung injury was associated with decreased surfactant protein (SP) A (show SFTPA1 Antibodies) and SPC (show SFTPC Antibodies) but not SPB and SPD (show SFTPD Antibodies) expression.

  2. Surfactant protein B suppresses lung cancer progression by inhibiting secretory phospholipase A2 (show YWHAZ Antibodies) activity and arachidonic acid production.

  3. Surfactant protein B had decreased levels in influenza A virus PR8-infected cells, which was confirmed by immunoblotting and immunofluorescence assays.

  4. macrophages participate in the repression of SFTPB expression by LPS (show TLR4 Antibodies), and that macrophage-released cytokines (including TNF (show TNF Antibodies)) regulate the transcription factor CEBPB (show CEBPB Antibodies)

  5. ErbB4 regulates the expression of surfactant protein B in fetal lung maturation, helping to prepare for the fetal-neonatal transition.

  6. The stimulatory effects of estrogen on Sftpb are under transcriptional control of ErbB4 (show ERBB4 Antibodies).

  7. SP-B contributes to innate host defense of the lung by supplementing the nonoxidant antimicrobial defenses of alveolar macrophages

  8. DNA methylation and chromatin modifications cooperate with Nkx2-1 to regulate Sftpb gene cell specific expression.

  9. formation of the intersubunit disulfide bridge is not critical for SP-B function

  10. The late asthmatic response is linked with increased surface tension and reduced surfactant protein B in mice.

Pig (Porcine) Surfactant Associated Protein B (SFTPB) interaction partners

  1. Data show that detergent-solubilized surfactant protein B (SP-B) indicate the presence of 10 nm ring-shaped particles.

  2. Data suggest that transient exposure of surfactant to polymers like hyaluronan (HA) could be a promising strategy for the production of more efficient therapeutic surfactants SP-A (show SFTPA1 Antibodies), SP-B and SP-C (show SFTPC Antibodies) preparations.

  3. Data indicate that in the background of phosphatidylcholine (POPC) membranes pulmonary surfactant protein SP-B exhibits a certain level of selectivity for anionic fluorescent phospholipids over the corresponding zwitterionic analogues.

  4. SP-B and SP-C (show SFTPC Antibodies) proteins promote the formation of proteolipid channels in which lipid molecules are functionally involved.

  5. Palmitoylation is key for the functional cooperation of SP-C with SP-B that enables cholesterol-containing surfactant films to reach very low tensions under compression.

  6. Surfactant protein SP-B promoted film formation and reextension to lower surface tensions than SP-C (show SFTPC Antibodies).

  7. The role of the SP-B NH(2) terminus in the formation and stability of cylindrical structures, specifically the distribution of lipid stack height, width, and density with four SP-B truncation peptides, was studied.

  8. SP-B is unlikely to affect uptake of surfactant

  9. The presence of phosphatidylglycerol iz required for SP-B to acquire the appropriate tertiary folding.

  10. SFTPB is located on pig chromosome 3, and is secreted by pulmonary alveolar type II epithelial cells. It is down-regulated during Actinobacillus pleuropneumoniae lung infection.

Cow (Bovine) Surfactant Associated Protein B (SFTPB) interaction partners

  1. Measurements of the depth of SP-B(CTERM) indicated the peptide center positions ~8A more deeply than the phosphate headgroups, a topology that may allow the peptide to promote functional lipid structures without causing micellization upon compression.

  2. results suggest the hydrophobic surfactant protein, SP-B, protects alveolar surfactant phospholiopids from hydrolysis mediated by multiple sPLA(2 (show PLA2G2A Antibodies)) in both vesicles (alveolar subphase) and monomolecular films (air-liquid interface)

  3. The hydrophobic surfactant proteins SP-B and SP-C (show SFTPC Antibodies) induce formation of bicontinuous inverse cubic phases.

  4. Reactive oxygen species inactivation of lipid extract surfactant B (SP-B) biophysical activity appears to involve modification of a maximum of three amino acids: Trp9, Met29, and Met65.

SFTPB Antigen Profile

Protein Summary

This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with SFTPB

  • surfactant protein B (SFTPB) antibody
  • surfactant associated protein B (Sftpb) antibody
  • surfactant protein B (Sftpb) antibody
  • surfactant, pulmonary-associated protein B L homeolog (sftpb.L) antibody
  • AI562151 antibody
  • PSP-B antibody
  • SF-B antibody
  • SFTB3 antibody
  • Sftp-3 antibody
  • Sftp3 antibody
  • sftpb antibody
  • SMDP1 antibody
  • Sp-b antibody
  • xSP-B antibody

Protein level used designations for SFTPB

18 kDa pulmonary-surfactant protein , 6 kDa protein , pulmonary surfactant-associated protein B , pulmonary surfactant-associated proteolipid SPL(Phe) , surfactant associated protein B , surfactant pulmonary-associated protein B , surfactant, pulmonary-associated protein B , SP-B , surfactant protein B , surfactant, pulmonary-associated protein B L homeolog

GENE ID SPECIES
6439 Homo sapiens
20388 Mus musculus
192155 Rattus norvegicus
397296 Sus scrofa
507398 Bos taurus
100379548 Cavia porcellus
100688334 Canis lupus familiaris
779297 Xenopus laevis
Selected quality suppliers for anti-SFTPB (SFTPB) Antibodies
Did you look for something else?