Synaptonemal Complex Protein 3 Proteins (SYCP3)

SYCP3 encodes an essential structural component of the synaptonemal complex. Additionally we are shipping SYCP3 Antibodies (107) and SYCP3 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SYCP3 20962 P70281
SYCP3 50511 Q8IZU3
SYCP3 25561 Q63520
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Top SYCP3 Proteins at

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Yeast Golden Syrian Hamster His tag   1 mg Log in to see 60 to 71 Days
Yeast Cynomolgus His tag   1 mg Log in to see 60 to 71 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days

SYCP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,
Rat (Rattus)

More Proteins for Synaptonemal Complex Protein 3 (SYCP3) Interaction Partners

Zebrafish Synaptonemal Complex Protein 3 (SYCP3) interaction partners

  1. Immunohistochemical observations revealed that Sycp3 is specifically localized in spermatocytes in typical nuclear patterns at each meiotic stage.

Mouse (Murine) Synaptonemal Complex Protein 3 (SYCP3) interaction partners

  1. SYCP1 (show SYCP1 Proteins) and SYCP3 act at the centromeres to promote the establishment and/or maintenance of centromere pairing and, by doing so, improve the segregation fidelity of mammalian meiotic chromosomes.

  2. Unlike other vertebrates, rat and mouse SYCP3 exists in 2 isoforms; the short isoform is conserved in vertebrates and the longer isoform, appeared 15 million years ago in a common ancestor of rat and mouse and after separation from the hamster branch.

  3. X-linked lymphocyte-regulated protein pM1 (XMR), XLR, and SCP3 render tumor cells resistant to antitumor immunity

  4. absence of synaptonemal complex protein 3 (SCP3) promotes aneuploidy in murine oocytes by inducing defective meiotic chromosome segregation

  5. In Scp3-deficient (knockout) mice, spermatogenesis and testicular degeneration are augmented when E2F1 (show E2F1 Proteins) is also deficient.

  6. Rad21 (show RAD21 Proteins), and the superimposed SCP3 and SCP2 (show CRISP3 Proteins), are involved in the monopolar attachment of sister kinetochores during meiosis I

  7. SYCP2 and SYCP3 proteins function in the specificity of chromatin attachment to the chromosome core

  8. SYCP3 has a temporally restricted role in maintaining, but not establishing, cohesin-core organization during prophase I.

  9. The SYCP3 is expressed in germ cell-like cells. The nuclear distribution of SYCP3 in the germ cell-like cells is highly abnormal and not associated with the chromosomes of these cells.

  10. DNA double-stranded breaks are inefficiently repaired in Sycp3(-)(/)(-) oocytes, thereby generating a temporal spectrum of recombination errors. T

Human Synaptonemal Complex Protein 3 (SYCP3) interaction partners

  1. SCP3 (show CTDSPL Proteins) is associated with lymphangiogenesis and provides insight into the SCP3 (show CTDSPL Proteins)-VEGF-C (show VEGFC Proteins)/VEGF-D (show Figf Proteins) axis based cancer therapy strategy.

  2. In the model, the reported compaction of chromosomal DNA caused by SYCP3 would result from its ability to bridge distant sites on a DNA molecule with the DNA-binding domains located at each end of its strut-like structure.

  3. SYCP3 binds to RAD51 (show RAD51 Proteins) and attenuates RAD51 (show RAD51 Proteins) activity during meiosis.

  4. SYCP3 binding and assembly on meiotic chromosomes leads to their organisation into compact structures compatible with recombination and crossover formation

  5. The T657C polymorphism of the SYCP3 gene is possibly associated with recurrent pregnancy loss of unknown cause in human.

  6. SCP3 (show CTDSPL Proteins) plays an important role in the progression of cervical cancer

  7. SYCP3 mutations are not associated with the genetic susceptibility for meiotic arrest in infertile male patients with nonobstructive azoospermia in the Turkish population

  8. screening for genetic variants in AURKB (show AURKB Proteins) and SYCP3 among these patients with reproductive problems using Sanger sequencing. Only one apparently non-pathogenic deletion was found in SYCP3.

  9. Positive synaptonemal complex protein 3 expression is a portent of poor outcome and may be a potential biomarker in the early stages of the non-small cell lung cancer for survival.

  10. mutations in SYCP3 do not contribute significantly to risk for recurrent miscarriage through maternal meiotic nondisjunction.

SYCP3 Protein Profile

Protein Summary

This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.

Gene names and symbols associated with SYCP3

  • choline phosphotransferase 1 (chpt1)
  • synaptonemal complex protein 3 (SYCP3)
  • synaptonemal complex protein 3 (sycp3)
  • synaptonemal complex protein 3 (scp3)
  • synaptonemal complex protein 3 L homeolog (sycp3.L)
  • synaptonemal complex protein 3 (Sycp3)
  • COR1 protein
  • fd50f07 protein
  • MGC146429 protein
  • RNASCP3 protein
  • SCP-3 protein
  • SCP3 protein
  • SPGF4 protein
  • SYCP3 protein
  • wu:fb67a04 protein
  • wu:fd50f07 protein

Protein level used designations for SYCP3

cholinephosphotransferase 1 , diacylglycerol cholinephosphotransferase 1 , synaptonemal complex protein 3 , SCP-3 , synaptonemal complex protein 3-like , Meiotic chromosome core protein , Synaptonemal complex protein COR1

322605 Danio rerio
418097 Gallus gallus
452174 Pan troglodytes
779673 Xenopus (Silurana) tropicalis
100049288 Oryzias latipes
100136243 Oncorhynchus mykiss
100137700 Xenopus laevis
20962 Mus musculus
50511 Homo sapiens
25561 Rattus norvegicus
615896 Bos taurus
101825388 Mesocricetus auratus
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