anti-Synemin, Intermediate Filament Protein (SYNM) Antibodies

The protein encoded by SYNM is an intermediate filament (IF) family member. Additionally we are shipping Synemin, Intermediate Filament Protein Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SYNM 23336 O15061
SYNM 233335 Q70IV5
SYNM 308709  
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Top anti-Synemin, Intermediate Filament Protein Antibodies at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat heart labeled with Rabbit Anti Desmuslin Polyclonal Antibody, Unconjugated (ABIN1387897) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Mouse Un-conjugated IHC, IHC (p), WB   100 μL Log in to see 11 to 14 Days
$507.83
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Human Mouse Un-conjugated IHC, IHC (p)   100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . 200 μL Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged SYNM is 0.3 ng/ml as a capture antibody. 50 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit HRP ELISA   100 μg Log in to see 11 to 16 Days
$412.19
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Human Rabbit Biotin ELISA   100 μg Log in to see 11 to 16 Days
$412.19
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Human Rabbit FITC ELISA   100 μg Log in to see 11 to 16 Days
$412.19
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Human Rabbit Un-conjugated ELISA, IF/ICC, IHC   100 μg Log in to see 11 to 16 Days
$412.19
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB   100 μg Log in to see 13 to 16 Days
$430.77
Details

Top referenced anti-Synemin, Intermediate Filament Protein Antibodies

  1. Human Polyclonal SYNM Primary Antibody for IF (p), IHC (p) - ABIN1387897 : Bengoechea, Pittman, Tuck, True, Weihl: Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D. in Human molecular genetics 2015 (PubMed)

More Antibodies against Synemin, Intermediate Filament Protein Interaction Partners

Human Synemin, Intermediate Filament Protein (SYNM) interaction partners

  1. LMOD1, SYNPO2, PDLIM7, PLN, and SYNM down-regulation reflect the altered phenotype of smooth muscle cells in vascular disease and could be early sensitive markers of SMC dedifferentiation.

  2. alpha-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin

  3. Immunohistochemistry of synemin in reactive astrocytes and Rosenthal fibers in two patients with Alexander disease. There was an abundance of GFAP-positive Rosenthal fibers and widespread reactive gliosis in the white matter and subpial regions.

  4. synemin positively regulates glioblastoma cell proliferation by helping sequester PP2A away from Akt, thereby favoring Akt activation.

  5. Synemin knock-down did not influence the cytoskeleton expression and organization of human Chang liver cells

  6. SYNM could represent a novel putative breast tumor suppressor gene that is prone to epigenetic silencing. SYNM promoter methylation may become a useful predictive biomarker to stratify breast cancer patients' risk for tumor relapse.

  7. Desmuslin expression is required for the maintenance of vascular smooth muscle phenotype. Decreased desmuslin expression may affect differentiation of VSMCs and ultimately contribute to the development of varicose veins.

  8. The differences in human syncoilin and beta-synemin mRNA ratios between Duchenne muscular dystrophy and normal muscles were not statistically significant

  9. The LIM domain protein zyxin was identified as an interaction partner for human synemin.

  10. Genomic organization and single-nucleotide polymorphism map of desmuslin, a novel intermediate filament protein on chromosome 15q26.3.

  11. Expression of the intermediate filament protein synemin in myofibrillar myopathies and other muscle diseases.

  12. the default of KIAA0353 gene may play a role in the occurrence and development of varicose great saphenous vein in PDVI patients.

  13. The colocalization of Synemin [syn] with vimentin, GFAP, or neurofilament supports the idea that Syn is a key cross-linking protein in morphogenesis that connects different cytoskeletal structures

  14. Based on its localization and its expression pattern, beta-synemin functions as a structural protein involved in maintaining muscle integrity through its interactions with alpha-dystrobrevin, desmin, and other structural proteins.

  15. synemin is associated with ruffled membranes in addition to being distributed along the intermediate filament network

  16. Desmuslin is down-regulated in incompetent saphenous veins.

  17. Mammalian synemin is also shown to colocalize with dystrophin within muscle cell cultures

  18. The stability of DMN was analyzed under the action of low-level laser therapy.

  19. alpha-synemin, but not beta-synemin, interacts with both vinculin and metavinculin

  20. results revealed that synemin was modulated nearly in all human human hepatocellular carcinoma cases

Mouse (Murine) Synemin, Intermediate Filament Protein (SYNM) interaction partners

  1. Suggest that synemin contributes to linkage between costameres and the contractile apparatus and that the absence of synemin results in decreased fiber size and increased sarcolemmal deformability and susceptibility to injury.

  2. results show that synemin is necessary to maintain membrane integrity and regulates signalling molecules during muscle hypertrophy.

  3. alpha-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titin

  4. synemin gene encodes proteins belonging to the intermediate filament which confer resistance to mechanical stress and modulate cell shape.

  5. Dmn is expressed in reactive astrocytes in neurotrauma and interacts differentially with Vim and Gfap.

  6. Alpha- and beta-synemin transcripts and their encoded proteins colocalize in neurons, especially in the midbrain and pons.

  7. Synemin isoforms during mouse development.

  8. These analyses show that synemin transcript and its encoded protein colocalize in the anterior horn cells and that no differences in synemin expression were found in nerve tissue from C57BL/6 or mdx mice.

Synemin, Intermediate Filament Protein (SYNM) Antigen Profile

Protein Summary

The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with SYNM

  • synemin (SYNM) antibody
  • synemin, intermediate filament protein (synm) antibody
  • synemin, intermediate filament protein (Synm) antibody
  • synemin (Synm) antibody
  • 4930412K21Rik antibody
  • AI852401 antibody
  • Dmn antibody
  • E130104F11 antibody
  • si:dkey-25f3.3 antibody
  • Syn antibody
  • Synemin antibody

Protein level used designations for SYNM

desmuslin , intermediate filament protein synemin , synemin, intermediate filament protein , synemin , synemin alpha , synemin beta

GENE ID SPECIES
100008842 Oryctolagus cuniculus
467773 Pan troglodytes
479024 Canis lupus familiaris
558800 Danio rerio
717194 Macaca mulatta
100020187 Monodelphis domestica
100401502 Callithrix jacchus
100587905 Nomascus leucogenys
23336 Homo sapiens
233335 Mus musculus
308709 Rattus norvegicus
514186 Bos taurus
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