anti-Synovial Sarcoma, X Breakpoint 1 (SSX1) Antibodies

The product of SSX1 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. Additionally we are shipping Synovial Sarcoma, X Breakpoint 1 Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SSX1 6756 Q16384
SSX1 691903  
SSX1    
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Top anti-Synovial Sarcoma, X Breakpoint 1 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SSX1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated FACS, ICC, IF, IHC, IHC (p), WB Flow Cytometry: SSX1 Antibody (1E10) [NBP2-00614] - Analysis of Hela cells, using anti-SSX1 antibody, (Red), compared to a nonspecific negative control antibody (Blue). Immunohistochemistry-Paraffin: SSX1 Antibody (1E10) [NBP2-00614] - Staining of paraffin-embedded Human Kidney tissue using anti-SSX1 mouse monoclonal antibody. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 11 to 14 Days
$537.17
Details
Human Mouse Un-conjugated WB Western Blot analysis of SSX1 expression in transfected 293T cell line by SSX1 MaxPab polyclonal antibody.Lane 1: SSX1 transfected lysate(20.68 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated FACS, ICC, IF, IHC, WB   100 μg Log in to see 8 to 11 Days
$658.23
Details
Human Rabbit Biotin ELISA   100 μg Log in to see 11 to 16 Days
$412.19
Details

Top referenced anti-Synovial Sarcoma, X Breakpoint 1 Antibodies

  1. Human Polyclonal SSX1 Primary Antibody for WB - ABIN2787447 : Törnkvist, Natalishvili, Xie, Girnita, DArcy, Brodin, Axelson, Girnita: Differential roles of SS18-SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against Synovial Sarcoma, X Breakpoint 1 Interaction Partners

Human Synovial Sarcoma, X Breakpoint 1 (SSX1) interaction partners

  1. SS18-SSX1 deregulates developmental programs to drive transformation by hijacking a transcriptional repressive complex to aberrantly activate gene expression

  2. Synovial sarcoma (SS) is considered as high-grade tumors with a poor prognosis. Novel therapies targeted at fusion oncogene, SS18-SSX-derived peptide vaccine, epidermal growth factor receptor, and vascular endothelial growth factor are the future hope in SS.

  3. Data indicate that the oncogene SS18-SSX1 promotes tumorigenesis by increasing the expression of SHC SH2-domain binding protein 1 (SHCBP1), which normally acts as a tumor promoting factor.

  4. In patients with Colon cancer, the expression of SSX1 gene was associated with a poor prognosis.

  5. Meta-analysis of human synovial sarcoma patient series identified two tumor-gentoype-phenotype correlations that were not modeled by the mice, namely a scarcity of male hosts and biphasic histologic features among SS18-SSX2 tumors. Re-analysis of human SS18-SSX1 and SS18-SSX2 tumor transcriptomes demonstrated very few consistent differences, but highlighted increased native SSX2 expression in SS18-SSX1 tumors.

  6. Data show that SS18/SSX tightly regulates the elevated expression of the key Wnt target AXIN2 in primary synovial sarcoma.

  7. a rare variant of the SS18-SSX1 fusion transcript, which could not be identified by routine procedures for genetic diagnosis, was detected. In addition, 8 missense mutations of cancer-related genes were confirmed

  8. SS18-SSX-induced Wnt/beta-catenin signaling appears to be of crucial biological importance in synovial sarcoma tumorigenesis and progression.

  9. The mRNA levels of SSX1 and SSX4 are associated with multiple myeloma clinical stage

  10. These results suggest that the characteristic speckle localization pattern of SS18-SSX is strongly involved in the tumorigenesis through the SSX moiety of the SS18-SSX fusion protein.

  11. Knockdown of SS18-SSX1 in synovial sarcoma inhibits viability and induces apoptosis.

  12. Study shows that the SS18-SSX1 oncogenic fusion usurps SWI/SNF-like BAF complexes, resulting in activation of Sox2, which drives proliferation.

  13. siRNA targeting of SS18-SSX1 has therapeutic potential for the treatment of synovial sarcoma.

  14. epigenetic features may define the cellular microenvironment in which SYT-SSX displays its functional effects

  15. existence of fusion with SYT in synovial sarcoma

  16. A synovial sarcoma of classic morphology contained a novel t(20;X) SS18L1(strong homology to SS18 on Ch20)/SSX1 fusion transcript in which nucleotide 1216 (exon 10) of SS18L1 was fused in-frame with nucleotide 422 (exon 6) of SSX1.

  17. RT-PCR detection of SSX1 in paraffin-embedded tissue allowed for molecular diagnosis of synovial sarcoma.

  18. demonstrate differentially expressed genes for the 2 major gene fusion variants in SS, chromosome 18 synovial sarcoma (SS18)/SSX1 and SS18/SSX2, and thereby suggest that these result in different downstream effects

  19. SYT-SSX1 induces insulin-like growth factor II expression in fibroblast cells.

  20. In conclusion, SS18-SSX and IGF-1R seem to play important but different roles in maintaining malignant growth of synovial sarcoma cells.

Synovial Sarcoma, X Breakpoint 1 (SSX1) Antigen Profile

Protein Summary

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X\\\\;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity.

Gene names and symbols associated with SSX1

  • SSX family member 1 (SSX1) antibody
  • SSX family member 1 (Ssx1) antibody
  • protein SSX1 (LOC736918) antibody
  • CT5.1 antibody
  • SSRC antibody

Protein level used designations for SSX1

protein SSX1 , cancer/testis antigen 5.1 , cancer/testis antigen family 5, member 1 , sarcoma, synovial, X-chromosome-related 1 , synovial sarcoma, X breakpoint 1

GENE ID SPECIES
6756 Homo sapiens
691903 Rattus norvegicus
736918 Pan troglodytes
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