TAF1 Proteins
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides.
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TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor (TAF1) (AA 1379-1636) protein (His tag,T7 tag) Protein
TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor (TAF1) Protein Protein
TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor (TAF1) protein (GST tag) Protein
TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor (TAF1) protein (GST tag) Protein
TAF1 Protein Profile
Protein Summary
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. This gene is part of a complex transcriptional unit (TAF1/DYT3), wherein some products share exons with TAF1 as well as additional exons downstream.
Gene names and symbols associated with TAF1
- TATA-box binding protein associated factor 1 (Taf1) antibody
- TATA-box binding protein associated factor 1 (TAF1) antibody
- 250kDa antibody
- AU015687 antibody
- B430306D02Rik antibody
- BA2R antibody
- Ccg-1 antibody
- CCG1 antibody
- CCGS antibody
- DYT3 antibody
- DYT3/TAF1 antibody
- KAT4 antibody
- N-TAF1 antibody
- NSCL2 antibody
- OF antibody
- P250 antibody
- TAF2A antibody
- TAFII250 antibody
- XDP antibody
Protein level used designations for TAF1
TAF(II)250 , TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, neuron specific isoform , TAFII-250 , TBP-associated factor 250 kDa , cell cycle gene 1 protein , cell cycle, G1 phase defect , p250 , transcription initiation factor TFIID 250 kDa subunit , transcription initiation factor TFIID subunit 1 , complementation of cell cycle block, G1-to-S , transcription factor TFIID p250 polypeptide
| GENE ID | SPECIES |
|---|---|
| 270627 | Mus musculus |
| 6872 | Homo sapiens |