Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Acts as a GTPase activating protein for RAB5. Additionally we are shipping TBC1 Domain Family, Member 3 Proteins (4) and and many more products for this protein.
Showing 10 out of 42 products:
our work reveals a novel model by which CaM promotes cell migration through inhibiting the ubiquitination and degradation of TBC1D3.
Here, the found that expression of TBC1D3 in ventricular cortical progenitors of mice via in utero electroporation caused delamination of ventricular radial glia cells (vRGs) and promoted generation of self-renewing basal progenitors with typical morphology of outer radial glia (oRG), which are most abundant in primates. Expression of TBC1D3, was often found to underlie cortical regions exhibiting folding.
High TBC1B3 expression is associated with breast cancer.
these studies indicate a novel model by which the microtubule network regulates EGFR stability and signaling through tubulin dimer/oligomer interaction with the nucleocytoplasmic protein TBC1D3.
TBC1D3 is targeted to the plasma membrane by protein palmitoylation.
Growth factor-stimulated TBC1D3 ubiquitination and degradation are regulated by its interaction with CUL7-Fbw8.
TBC1D3 plays an unanticipated and potentially unique role in the fine-tuning of insulin/IGF-1 signaling
We describe eight highly related TBC1D3 paralogues located on Chromosome 17q12 that display specific transcription patterns in human tissues, and that pattern is altered in several primary prostate tumors in comparison to healthy prostate tissues.
Altered growth factor receptor trafficking and GTP-Ras turnover may be sites where recently evolved genes such as TBC1D3 selectively modulate signaling in hominoids and humans
Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).
Rab GTPase-activating protein PRC17
, TBC1 domain family member 3
, TBC1 domain family, member 3F
, prostate cancer gene 17 protein
, protein TRE17-alpha