anti-THAP Domain Containing 11 (THAP11) Antibodies

The protein encoded by THAP11 contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases.. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
THAP11 307806  
THAP11 57215 Q96EK4
THAP11 59016 Q9JJD0
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Top anti-THAP11 Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA   100 μg 6 to 7 Days
$291.53
Details
Human Rabbit Un-conjugated EIA, WB THAP11 Antibody (N-term) western blot analysis in WiDr cell line lysates (35 µg/lane). This demonstrates the THAP11 antibody detected the THAP11 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Flow cytometric analysis of Hela cells using THAP11 mouse mAb (green) and negative control (purple) . Figure 2: Immunofluorescence analysis of NTERA-2 cells using THAP11 mouse mAb (green) . Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. 100 μL 3 to 4 Days
$393.80
Details
Human Mouse Un-conjugated ELISA, FACS, IF, IHC, WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated ELISA, FACS, IF/ICC, IHC, WB 100 μL 11 to 16 Days
$469.05
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Anti-CTG-B45d / THAP11 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 0.05 mg 11 to 14 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Goat Un-conjugated ELISA   0.1 mg 2 to 3 Days
$446.88
Details
Human Mouse Un-conjugated ELISA, FACS, IF, IHC (p), WB Western blot analysis using THAP11 monoclonal antobody, clone 3F3 against HeLa (1) and NTERA-2 (2) cell lysate. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue (A) and ovary cancer tissue (B) using THAP11 monoclonal antobody, clone 3F3 with DAB staining. 100 μL 11 to 12 Days
$374.67
Details

Top referenced anti-THAP11 Antibodies

  1. Human Monoclonal THAP11 Primary Antibody for BI, IF - ABIN2689892 : Dejosez, Levine, Frampton, Whyte, Stratton, Barton, Gunaratne, Young, Zwaka: Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells. in Genes & development 2010 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal THAP11 Primary Antibody for ICC, FACS - ABIN969436 : Li, McInnis, Margolis, Antonarakis, Ross: Novel triplet repeat containing genes in human brain: cloning, expression, and length polymorphisms. in Genomics 1993 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal THAP11 Primary Antibody for IF, WB - ABIN528142 : Nakamura, Yokota, Tan, Nagata, Takemura, Hirano, Shigeno, Shibata, Fujisawa, Ohnishi: Down-regulation of Thanatos-associated protein 11 by BCR-ABL promotes CML cell proliferation through c-Myc expression. in International journal of cancer. Journal international du cancer 2011 (PubMed)

  4. Cow (Bovine) Polyclonal THAP11 Primary Antibody for ELISA - ABIN4247424 : Zhu, Li, Li, Zhan, Li, Xu, Xu, Sun, Yang: Cell growth suppression by thanatos-associated protein 11(THAP11) is mediated by transcriptional downregulation of c-Myc. in Cell death and differentiation 2009 (PubMed)

More Antibodies against THAP11 Interaction Partners

Human THAP Domain Containing 11 (THAP11) interaction partners

  1. A transcriptional repressor network including THAP domain containing 11 protein (THAP11) was identified and negatively regulates endogenous PARKIN abundance.

  2. We sequenced THAP11 by Sanger sequencing and discovered a potentially pathogenic, homozygous variant in THAP11, c.240C > G (p.Phe80Leu). Further, we provide functional data in model organisms that suggests that both HCFC1 and THAP11 are essential for normal brain development and neural precursor differentiation.

  3. the crystal structure of the C-ter region of THAP11 forms a left-handed parallel homo-dimeric coiled-coil structure possessing several unusual features.

  4. The M4 motif (ACTAYRNNNCCCR) is a functional regulatory bipartite cis-element, which engages a THAP11/HCF-1 complex via binding to the ACTAYR module, while the CCCRRNRNRC subsequence part constitutes a binding platform for Ikaros and NFKB1

  5. THAP11, ZNF143, and HCF-1 form a mutually dependent complex on chromatin, which is independent of E2F occupancy.

  6. that THAP11 reversibly regulated erythroid and megakaryocytic differentiation.

  7. HCFC1 is a common component of active human CpG-island promoters and coincides with ZNF143, THAP11, YY1, and GABP transcription factor occupancy.

  8. In HCC patients, the expression of THAP11 mRNA significantly correlated with PCBP1 mRNA expression. Our results suggest a novel role of THAP11 in CD44 alternative splicing and hepatoma invasion

  9. identify THAP11 as a transcriptional regulator differentially expressed in human colon cancer

  10. the induced THAP11 might be one of transcriptional regulators of c-Myc expression in CML cell.

  11. Results suggest that THAP11 functions as a cell growth suppressor by negatively regulating the expression of c-Myc.

Mouse (Murine) THAP Domain Containing 11 (THAP11) interaction partners

  1. The activity of Ronin coincided with the recruitment of its cofactor, Hcf-1, and the elevation of H3K4me3 levels at specific target genes, suggesting the involvement of an epigenetic mechanism.

  2. Ronin binds to and regulates the genes encoding several DNA repair factors, including Gtf2h4 and Rad18, providing a potential mechanism for this phenotype.

  3. Ronin is a positive regulator of mitochondrial gene expression that coordinates mitochondrial activity and cell cycle progression in the developing retina.

  4. Ronin/Hcf-1 controls a genetic program that contributes to the unimpeded growth of embryonic stem cells.

  5. Findings identify Ronin as an essential factor underlying embryogenesis and ES cell pluripotency; its association with HCF-1 suggests an epigenetic mechanism of gene repression in pluripotent cells.

THAP11 Antigen Profile

Protein Summary

The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases.

Gene names and symbols associated with THAP11

  • THAP domain containing 11 (Thap11) antibody
  • THAP domain containing 11 L homeolog (thap11.L) antibody
  • THAP domain containing 11 (THAP11) antibody
  • THAP domain containing 11 (thap11) antibody
  • THAP domain-containing protein 11 (tha11) antibody
  • 2810036E22Rik antibody
  • AB041579 antibody
  • CTG-B43a antibody
  • CTG-B45d antibody
  • Ronin antibody
  • wu:fa14e04 antibody
  • wu:fc33b05 antibody
  • zgc:65871 antibody
  • zgc:76876 antibody

Protein level used designations for THAP11

THAP domain-containing protein 11 , THAP domain containing 11

GENE ID SPECIES
307806 Rattus norvegicus
432088 Xenopus laevis
454176 Pan troglodytes
489752 Canis lupus familiaris
700354 Macaca mulatta
100037892 Xenopus (Silurana) tropicalis
100195455 Salmo salar
57215 Homo sapiens
59016 Mus musculus
539845 Bos taurus
406390 Danio rerio
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