THO Complex 6 Homolog (Drosophila) Proteins (THOC6)

Component of the THO subcomplex of the TREX complex. Additionally we are shipping THOC6 Antibodies (44) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
THOC6 79228 Q86W42
THOC6 386612 Q5U4D9
Rat THOC6 THOC6 79227 Q6AY87
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Top THOC6 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

THOC6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for THO Complex 6 Homolog (Drosophila) (THOC6) Interaction Partners

Human THO Complex 6 Homolog (Drosophila) (THOC6) interaction partners

  1. Results indicate three unrelated patients with bi-allelic mutations in THOC6 associated with intellectual disability and additional clinical features.

  2. In addition to confirming the morbid nature of THOC6 by providing an independent homozygous apparently loss of function allele in a patient with a compatible phenotype, our data also expand THOC6-related phenotype to include previously unreported imperforate anus and undescended testicles.

THOC6 Protein Profile

Protein Summary

Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex (By similarity).

Gene names and symbols associated with THOC6

  • THO complex 6 (THOC6)
  • THO complex 6 homolog (Drosophila) (thoc6)
  • THO complex 6 (thoc6)
  • THO complex 6 (Thoc6)
  • F830014G06Rik protein
  • fSAP35 protein
  • Pdrp protein
  • Wdr58 protein
  • zgc:101618 protein

Protein level used designations for THOC6

WD repeat domain 58 , THO complex subunit 6 homolog , WD repeat-containing protein 58 , THO complex 6 homolog (Drosophila) , THO complex subunit 6 homolog-like , functional spliceosome-associated protein 35

GENE ID SPECIES
453854 Pan troglodytes
700217 Macaca mulatta
100196413 Salmo salar
100414440 Callithrix jacchus
100432073 Pongo abelii
100587297 Nomascus leucogenys
100004014 Danio rerio
79228 Homo sapiens
479871 Canis lupus familiaris
100125940 Bos taurus
386612 Mus musculus
79227 Rattus norvegicus
Selected quality suppliers for THOC6 Proteins (THOC6)
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