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THOC6 Products

(THO Complex 6 Homolog (THOC6))

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Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex (By similarity).

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Featured THOC6 Categories

THOC6 Antibodies

High quality antibodies with extensive validation data.

THOC6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended THOC6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (2)
  • (6)
Cat. No. ABIN566350
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN574461
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7172063
Quantity 100 μL
Datasheet Datasheet

Recommended THOC6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232838
Quantity 96 tests
Datasheet Datasheet

Recommended THOC6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322703
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322705
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322707
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our THOC6 products

Katahira, Okuzaki, Inoue, Yoneda, Maehara, Ohkawa: "Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I." in: Nucleic acids research, Vol. 41, Issue 14, pp. 7060-72, (2013) (PubMed).

Katahira, Inoue, Hurt, Yoneda: "Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA." in: The EMBO journal, Vol. 28, Issue 5, pp. 556-67, (2009) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Synonyms and alternative names related to THOC6

THO complex 6 (THOC6), THO complex 6 (Thoc6), THO complex 6 (thoc6), THO complex 6 homolog (Drosophila) (thoc6), THO complex 6 L homeolog (thoc6.L), F830014G06Rik, fSAP35, Pdrp, thoc6, WDR58, Wdr58, zgc:101618

Protein level used designations for THOC6

  • THO complex subunit 6 homolog
  • WD repeat domain 58
  • WD repeat-containing protein 58
  • functional spliceosome-associated protein 35
  • THO complex 6 homolog (Drosophila)
  • THO complex subunit 6 homolog-like
  • THO complex 6 L homeolog
  • THO complex 6 homolog
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