anti-TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) Antibodies

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Additionally we are shipping TIFA Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TIFA 92610 Q96CG3
Anti-Mouse TIFA TIFA 211550 Q793I8
Anti-Rat TIFA TIFA 310877 Q5XIB9
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Top anti-TIFA Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TIFA Antibody (N-term) in CEM cell line lysates (35 µg/lane). TIFA (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of TIFA Antibody (N-term) (ABIN653538) in CEM cell line lysates (35 µg/lane). TIFA (arrow) was detected using the purified polyclonal antibody. Anti-TIFA Antibody (N-term) at 1:2000 dilution + Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 21 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: TIFA Antibody  - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleus, nucleoli & cytosol. Western Blot: TIFA Antibody  250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells). 0.1 mL Log in to see 34 Days
$491.63
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical staining of human pancreas with TIFA polyclonal antibody  shows strong nuclear positivity in exocrine glandular cells at 1:200-1:500 dilution. Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate). Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with TIFA polyclonal antibody . 100 μL Log in to see 11 to 12 Days
$460.00
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details

More Antibodies against TIFA Interaction Partners

Human TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) interaction partners

  1. TIFA (show IL22 Antibodies) may serve as a biomarker in the prediction of lung adenocarcinoma. Furthermore, TIFA (show IL22 Antibodies) may modulate lung cancer cell survival and proliferation through regulating the synthesis of apoptosis-associated proteins.

  2. TIFA (show IL22 Antibodies) is a crucial mediator in the endothelial innate immune response by potentiating and amplifying NLRP3 (show NLRP3 Antibodies) inflammasome via augmenting signals 1 and 2

  3. study revealed that host TIFA (show IL22 Antibodies) and H. pylori-derived heptose-1,7-bisphosphate are critical effectors of innate immune signaling that account for much of the inflammatory response to H. pylori in gastric epithelial cells

  4. These results define TIFA (show IL22 Antibodies) as a rheostat for intracellular bacterial replication, escalating the immune response to invasive Gram-negative bacteria that exploit the host cytosol for growth.

  5. we report that Aurora A (show AURKA Antibodies) is essential for phosphorylation of the TRAF-interacting protein (show TANK Antibodies) TIFA (show IL22 Antibodies)

  6. This study reports the crystal structures of TIFA (show IL22 Antibodies) (residues 1-150, with the unstructured C-terminal tail truncated) and its complex with the N-terminal phosphothreonine9 peptide (residues 1-15).

  7. an innate immune signaling axis, mediated by phosphorylation-dependent oligomerization of the TRAF-interacting protein with forkhead-associated domain (TIFA) that is triggered by heptose-1,7-bisphosphate.

  8. identify a novel threonine phosphorylation site on TIFA (show IL22 Antibodies) and show that this phosphorylated threonine binds with the FHA (show CRY2 Antibodies) domain of TIFA (show IL22 Antibodies), leading to TIFA (show IL22 Antibodies) oligomerization and TIFA (show IL22 Antibodies)-mediated NF-kappaB (show NFKB1 Antibodies) activation

  9. TIFA (show IL22 Antibodies) induces the oligomerization and polyubiquitination of TRAF6 (show TRAF6 Antibodies), which leads to the activation of TAK1 (show MAP3K7 Antibodies) and IKK (show CHUK Antibodies) through a proteasome-independent mechanism

Mouse (Murine) TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) interaction partners

  1. The increase in TIFA level appears to be a feed-forward mechanism involved in TLR4 (show TLR4 Antibodies)/MyD88 (show MYD88 Antibodies)-dependent signaling, leading to NF-kappaB (show NFKB1 Antibodies) activation and HMGB1 (show HMGB1 Antibodies) release

  2. TIFA is likely to mediate IRAK-1 (show IRAK1 Antibodies)/TRAF6 (show TRAF6 Antibodies) interaction upon IL-1 (show IL1A Antibodies) stimulation

  3. We propose that ZCCHC11 (show ZCCHC11 Antibodies) is a unique TLR signal regulator, which interacts with TIFA after LPS (show TLR4 Antibodies) treatment and suppresses the TRAF6 (show TRAF6 Antibodies)-dependent activation of NF-kappaB (show NFKB1 Antibodies).

TIFA Antigen Profile

Protein Summary

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism (By similarity).

Gene names and symbols associated with TIFA

  • TRAF interacting protein with forkhead associated domain (TIFA) antibody
  • TRAF-interacting protein with forkhead-associated domain (tifa) antibody
  • TRAF-interacting protein with forkhead-associated domain (Tifa) antibody
  • TRAF-interacting protein with forkhead-associated domain S homeolog (tifa.S) antibody
  • Ab2-389 antibody
  • T2bp antibody
  • T6BP antibody
  • TIFA antibody
  • TIFAA antibody
  • xtifa antibody

Protein level used designations for TIFA

TRAF-interacting protein with forkhead-associated domain , TRAF-interacting protein with a forkhead-associated domain , TRAF-interacting protein with FHA domain-containing protein A , TRAF6-binding protein , TRAF2 binding protein , TRAF2-binding protein , TRAF6 binding protein , putative MAPK-activating protein PM14 , putative NF-kappa-B-activating protein 20 , Traf2 binding protein

GENE ID SPECIES
422692 Gallus gallus
471278 Pan troglodytes
487905 Canis lupus familiaris
100216213 Xenopus (Silurana) tropicalis
92610 Homo sapiens
211550 Mus musculus
310877 Rattus norvegicus
783855 Bos taurus
734184 Xenopus laevis
Selected quality suppliers for anti-TIFA (TIFA) Antibodies
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