anti-TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) Antibodies

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Additionally we are shipping TIFA Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TIFA 92610 Q96CG3
Anti-Mouse TIFA TIFA 211550 Q793I8
Anti-Rat TIFA TIFA 310877 Q5XIB9
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Top anti-TIFA Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TIFA Antibody (N-term) in CEM cell line lysates (35 µg/lane). TIFA (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB Western Blot at 1:2000 dilution + Hela whole cell lysate Lysates/proteins at 20 ug per lane. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$658.43
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 11 to 16 Days
$540.11
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 16 Days
$814.00
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 16 Days
$814.00
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 16 Days
$814.00
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$814.00
Details
Human Rabbit Cy5.5 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$416.90
Details

More Antibodies against TIFA Interaction Partners

Human TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) interaction partners

  1. TIFA expression limited proliferation of multiple myeloma cancer cells. In conclusion these results indicate that TIFA functions as a key transducer in DNA damage-induced NF-kappaB activation

  2. TIFA may serve as a biomarker in the prediction of lung adenocarcinoma. Furthermore, TIFA may modulate lung cancer cell survival and proliferation through regulating the synthesis of apoptosis-associated proteins.

  3. TIFA is a crucial mediator in the endothelial innate immune response by potentiating and amplifying NLRP3 inflammasome via augmenting signals 1 and 2

  4. study revealed that host TIFA and H. pylori-derived heptose-1,7-bisphosphate are critical effectors of innate immune signaling that account for much of the inflammatory response to H. pylori in gastric epithelial cells

  5. These results define TIFA as a rheostat for intracellular bacterial replication, escalating the immune response to invasive Gram-negative bacteria that exploit the host cytosol for growth.

  6. we report that Aurora A is essential for phosphorylation of the TRAF-interacting protein TIFA

  7. This study reports the crystal structures of TIFA (residues 1-150, with the unstructured C-terminal tail truncated) and its complex with the N-terminal phosphothreonine9 peptide (residues 1-15).

  8. an innate immune signaling axis, mediated by phosphorylation-dependent oligomerization of the TRAF-interacting protein with forkhead-associated domain (TIFA) that is triggered by heptose-1,7-bisphosphate.

  9. identify a novel threonine phosphorylation site on TIFA and show that this phosphorylated threonine binds with the FHA domain of TIFA, leading to TIFA oligomerization and TIFA-mediated NF-kappaB activation

  10. TIFA induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism

Mouse (Murine) TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA) interaction partners

  1. The increase in TIFA level appears to be a feed-forward mechanism involved in TLR4/MyD88-dependent signaling, leading to NF-kappaB activation and HMGB1 release

  2. TIFA is likely to mediate IRAK-1/TRAF6 interaction upon IL-1 stimulation

  3. We propose that ZCCHC11 is a unique TLR signal regulator, which interacts with TIFA after LPS treatment and suppresses the TRAF6-dependent activation of NF-kappaB.

TIFA Antigen Profile

Protein Summary

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism (By similarity).

Gene names and symbols associated with TIFA

  • TRAF interacting protein with forkhead associated domain (TIFA) antibody
  • TRAF-interacting protein with forkhead-associated domain (tifa) antibody
  • TRAF-interacting protein with forkhead-associated domain (Tifa) antibody
  • TRAF-interacting protein with forkhead-associated domain S homeolog (tifa.S) antibody
  • Ab2-389 antibody
  • T2bp antibody
  • T6BP antibody
  • TIFA antibody
  • TIFAA antibody
  • xtifa antibody

Protein level used designations for TIFA

TRAF-interacting protein with forkhead-associated domain , TRAF-interacting protein with a forkhead-associated domain , TRAF-interacting protein with FHA domain-containing protein A , TRAF6-binding protein , TRAF2 binding protein , TRAF2-binding protein , TRAF6 binding protein , putative MAPK-activating protein PM14 , putative NF-kappa-B-activating protein 20 , Traf2 binding protein

GENE ID SPECIES
422692 Gallus gallus
471278 Pan troglodytes
487905 Canis lupus familiaris
100216213 Xenopus (Silurana) tropicalis
92610 Homo sapiens
211550 Mus musculus
310877 Rattus norvegicus
783855 Bos taurus
734184 Xenopus laevis
Selected quality suppliers for anti-TIFA (TIFA) Antibodies
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