TIFA Proteins

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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8 Products
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3123994
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3074236
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 90 % by SDS - PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN668024
$646.15
Plus shipping costs $45.00
Delivery in 15 to 19 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 90 % pure
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2132179
$564.71
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
Recombinant Protein, Wheat germ (Source)
ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1322759
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityXenopus tropicalis
Application ELISA
Order details Cat. No. ABIN1511837
$2,414.50
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityXenopus laevis
Application ELISA
Order details Cat. No. ABIN1622654
$2,418.17
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
Recombinant Protein, Yeast (Source), Purity > 90 %
ReactivityCow (Bovine)
Application ELISA
Order details Cat. No. ABIN1460434
$2,440.17
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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TIFA Protein Profile

Protein Summary

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism (By similarity).

Gene names and symbols associated with TIFA

  • TRAF interacting protein with forkhead associated domain (TIFA) antibody
  • TRAF-interacting protein with forkhead-associated domain (tifa) antibody
  • TRAF-interacting protein with forkhead-associated domain (Tifa) antibody
  • TRAF-interacting protein with forkhead-associated domain S homeolog (tifa.S) antibody
  • Ab2-389 antibody
  • T2bp antibody
  • T6BP antibody
  • TIFA antibody
  • TIFAA antibody
  • xtifa antibody

Protein level used designations for TIFA

TRAF-interacting protein with forkhead-associated domain , TRAF-interacting protein with a forkhead-associated domain , TRAF-interacting protein with FHA domain-containing protein A , TRAF6-binding protein , TRAF2 binding protein , TRAF2-binding protein , TRAF6 binding protein , putative MAPK-activating protein PM14 , putative NF-kappa-B-activating protein 20 , Traf2 binding protein

GENE ID SPECIES
422692 Gallus gallus
471278 Pan troglodytes
487905 Canis lupus familiaris
100216213 Xenopus (Silurana) tropicalis
92610 Homo sapiens
211550 Mus musculus
310877 Rattus norvegicus
783855 Bos taurus
734184 Xenopus laevis
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