Tachykinin 3 (TAC3) ELISA Kits

TAC3 encodes a member of the tachykinin family of secreted neuropeptides. Additionally we are shipping Tachykinin 3 Antibodies (87) and Tachykinin 3 Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TAC3 21334 P55099
TAC3 6866 Q9UHF0
TAC3 29191 P08435
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Top Tachykinin 3 ELISA Kits at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 3.7 pg/mL 0.1-1.000 pg/mL   96 Tests 2 to 3 Days
$456.50
Details
Human 3.12 pg/mL 9.88 pg/mL - 800 pg/mL 96 Tests 13 to 16 Days
$700.00
Details
Cow 1.56 pg/mL n/a   96 Tests 15 to 18 Days
$1,026.67
Details
Rat 46.9 pg/mL 78 pg/mL - 5000 pg/mL A typical standard curve 96 Tests 13 to 16 Days
$641.23
Details
Guinea Pig
  96 Tests 15 to 18 Days
$707.14
Details
Chicken
  96 Tests 15 to 18 Days
$707.14
Details
Monkey
  96 Tests 15 to 18 Days
$707.14
Details
Pig
  96 Tests 15 to 18 Days
$707.14
Details
Rabbit
  96 Tests 15 to 18 Days
$707.14
Details
Sheep
  96 Tests 15 to 18 Days
$707.14
Details

Top referenced Tachykinin 3 ELISA Kits

  1. Human Tachykinin 3 ELISA Kit for Competition ELISA - ABIN1979212 : Topaloglu, Reimann, Guclu, Yalin, Kotan, Porter, Serin, Mungan, Cook, Ozbek, Imamoglu, Akalin, Yuksel, ORahilly, Semple: TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction. in Nature genetics 2009 (PubMed)
    Show all 6 Pubmed References

  2. Human Tachykinin 3 ELISA Kit for Competition ELISA - ABIN1979218 : Topaloglu, Reimann, Guclu, Yalin, Kotan, Porter, Serin, Mungan, Cook, Ozbek, Imamoglu, Akalin, Yuksel, ORahilly, Semple: TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction. in Nature genetics 2009 (PubMed)
    Show all 2 Pubmed References

  3. Human Tachykinin 3 ELISA Kit for Competition ELISA - ABIN1979215 : Page: Neurokinin B and pre-eclampsia: a decade of discovery. in Reproductive biology and endocrinology : RB&E 2010 (PubMed)
    Show all 2 Pubmed References

  4. Human Tachykinin 3 ELISA Kit - ABIN366958 : Abac?, Çatl?, An?k, Küme, Çalan, Dündar, Böber: Significance of serum neurokinin B and kisspeptin levels in the differential diagnosis of premature thelarche and idiopathic central precocious puberty. in Peptides 2015 (PubMed)

  5. Human Tachykinin 3 ELISA Kit for Competition ELISA - ABIN416907 : Parlak, Türkkahraman, Ellidağ, Çelmeli, Parlak, Yılmaz: Basal Serum Neurokinin B Levels in Differentiating Idiopathic Central Precocious Puberty from Premature Thelarche. in Journal of clinical research in pediatric endocrinology 2016 (PubMed)

More ELISA Kits for Tachykinin 3 Interaction Partners

Rhesus Monkey Tachykinin 3 (TAC3) interaction partners

  1. while collaborative kisspeptin and NKB signaling to GnRH neurons was active before puberty onset, after initiation of puberty the role of NKB signaling in GnRH neurons diminished and kisspeptin signaling assumed the primary stimulatory role in the regulation of GnRH release in male monkeys.

  2. Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin gene expression in the arcuate-median eminence.

Mouse (Murine) Tachykinin 3 (TAC3) interaction partners

  1. gene expression in the hypothalamus did not significantly change after 90 or 180 min restraint stress

  2. Incongruent pattern of neurokinin B expression in rat and mouse brains.

  3. Study in mice provide evidence for Tac2 as a strong candidate gene who likely plays a role in hippocampal stress processing and neural plasticity.

  4. steroidal environment and energy state negatively regulate kisspeptin (Kiss1), neurokinin B (Tac2), and dynorphin (Pdyn) gene expression.

  5. This study showed a new evidence that furthers our understanding for the mechanisms underlying Tac2-dependent cellular pathways in fear learning.

  6. Data show that estrogen receptor alpha (ERalpha) in tachykinin 2 protein (Tac2) neurons typically restrains pubertal onset and hypothalamic reproductive drive.

  7. Tac2-/- females had delays in sexual maturation, with time to vaginal opening and first estrus occurring later than controls. However, cycling recovered in adulthood and Tac2-/- females were fertile, although they produced fewer pups per litter.

  8. Increased Tac2 expression, through a stress-induced PTSD-like model, or following lentiviral CeA overexpression, are sufficient to enhance fear consolidation.

  9. Data indicate that in the arcuate nucleus, nearly 80% of enhanced green fluorescent protein (EGFP) neurons expressed pro-neurokinin B (NKB)-immunoreactivity.

  10. Data suggest that activation of neurokinin 3 and kappa-opioid receptors (NK3R and KOR) excites and inhibits kisspeptin, neurokinin B (NKB), and dynorphin (KNDy neurons).

  11. NKB could directly regulate secretion from NK3R-expressing GnRH neurons.

  12. Tac2 homozygous null mice responded normally to a series of algogenic (pain-inducing) and pruritic (itch-inducing) stimuli.

  13. Preprotachykinin (PPT)-B genes are expressed in uterine cells, oocytes, ovaries and embryos from mice, and may play a role in female reproductive function.

Human Tachykinin 3 (TAC3) interaction partners

  1. The administration of an NK3R antagonist indicates a role for Neurokinin B in the regulation of luteinising hormone (LH)/gonadotropin-releasing hormone (GnRH) in postmenopausal women, whereas the lack of response to kisspeptin may reflect the hypo-oestrogenic state. These data support a link of LH/GnRH pulsatility and vasomotor symptoms with NK3R antagonism as a potential therapeutic approach.

  2. Data suggest that basal serum neurokinin B level can be used as an adjunctive parameter to differentiate idiopathic central precocious puberty (ICPP) from premature thelarche (PT).

  3. acts through NK3 receptors in granulosa cells to stimulate steroid production

  4. mutations in TAC and TACR3 are not a common cause for ICPP.

  5. Plasma neurokinin B level is higher in patients with NDHT, indicating an unfavorable cardiovascular prognosis.

  6. Colocalization experiments provided evidence for the presence of cocaine- and amphetamine-regulated transcript (CART) in KP-immunoreactive (IR) and perikarya and in KP-IR and NKB-IR axon varicosities.

  7. Amino acid substitution A63P in TAC3 gene was statistically associated with the puberty onset time in Chinese girls.

  8. SP may influence the KP and NKB secretory output via additional autocrine/paracrine mechanisms or regulate GnRH neurosecretion directly.

  9. Copper can enter cultured astrocytoma cells and subsequently open plasma membrane calcium channels, but when bound to NKB, copper ion uptake is inhibited.

  10. Expression of the gene encoding NKB (TAC3) is up-regulated 20-fold in leiomyomas, compared with matched myometrium.

  11. Rare variants in the TAC3 and TACR3 genes were identified in patients with central pubertal disorders and loss-of-function variants of TACR3 were associated with the normosmic IHH phenotype.

  12. Interactions between kisspeptins and neurokinin B.

  13. Report neurokinin B immunoreactivity in the human brainstem.

  14. Sex differences in the neurokinin B system in the human infundibular nucleus.

  15. these immunohistochemical data suggest an aging-related moderate enhancement in central NKB signaling.

  16. NKB neurons in the arcuate nucleus do not synthesize detectable amounts of kisspeptin and dynorphin in young male humans. These data call for a critical use of the KNDy neuron terminology when referring to the pulse generator of the hypothalamus

  17. NKB/NK(3)R and kisspeptin/KISS1R are present in female peripheral reproductive tissues with colocalization of both systems in some non-neuronal cell populations of the human female genital tract.

  18. The gonadotropin axis dysfunction associated with nCHH due to TAC3/TACR3 mutations is related to a low GnRH pulsatile frequency leading to a low frequency of alpha-subunit pulses and to an elevated FSH/LH ratio.

  19. The significantly increased maternal plasma levels of NKB and ET-1 of patients with preeclampsia occur at early pregnancy, before the onset of clinical symptoms.

  20. Future studies will be needed to determine whether NKB signaling plays a permissive role in the onset of puberty--REVIEW

Pig (Porcine) Tachykinin 3 (TAC3) interaction partners

  1. mapping to chromosome 5

Tachykinin 3 (TAC3) Antigen Profile

Antigen Summary

This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with Tachykinin 3 (TAC3) ELISA Kits

  • tachykinin 3 (TAC3) antibody
  • tachykinin 2 (Tac2) antibody
  • tachykinin 3 (Tac3) antibody
  • HH10 antibody
  • NKB antibody
  • NKNB antibody
  • PPT-B antibody
  • PRO1155 antibody
  • Tac2 antibody
  • Tac3 antibody
  • ZNEUROK1 antibody

Protein level used designations for Tachykinin 3 (TAC3) ELISA Kits

tachykinin 3 , neurokinin B , preprotachykinin B , tachykinin 3 (neuromedin K, neurokinin beta) , PPT-B , neurokinin 2 , neurokinin A , neurokinin B-like protein Zneurok1 , neurokinin alpha , neuromedin L , neuropeptide K , preprotachykinin-B , substance K , tachykinin-3 , gamma tachykinin 3 , neuromedin K , tachykinin 2 , Neuromedin-K , neurokinin , neurokinin-B , neurokinin B, neuromedin K , tachykinin 3, neurokinin beta

GENE ID SPECIES
443213 Ovis aries
713978 Macaca mulatta
746748 Pan troglodytes
21334 Mus musculus
6866 Homo sapiens
29191 Rattus norvegicus
492314 Sus scrofa
281513 Bos taurus
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