anti-Taspase, Threonine Aspartase, 1 (TASP1) Antibodies

TASP1 encodes an endopeptidase that cleaves specific substrates following aspartate residues. Additionally we are shipping Taspase, Threonine Aspartase, 1 Proteins (8) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TASP1 75812 Q8R1G1
TASP1 311468  
TASP1 55617 Q9H6P5
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Taspase, Threonine Aspartase, 1 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TASP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate WB Suggested Anti-TASP1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: MCF7 cell lysate  TASP1 is supported by BioGPS gene expression data to be expressed in MCF7 100 μL 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated WB 100 μL 11 to 14 Days
$522.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of TASP1 C-term polyclonal antibody in mouse kidney tissue lysates. Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with hTASP1-C-term , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL 2 to 3 Days
$515.63
Details
Human Mouse Un-conjugated WB Western Blot analysis of TASP1 expression in transfected 293T cell line by TASP1 MaxPab polyclonal antibody.Lane 1: TASP1 transfected lysate(46.2 KDa).Lane 2: Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of mouse kidney, using TASP1 antibody (ABIN5972786). 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated WB TASP1 antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Details
Human Rabbit APC IHC, ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL 11 to 14 Days
$1,101.83
Details

Top referenced anti-Taspase, Threonine Aspartase, 1 Antibodies

  1. Human Polyclonal TASP1 Primary Antibody for IHC (p), ELISA - ABIN543416 : Hsieh, Cheng, Korsmeyer: Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression. in Cell 2003 (PubMed)

More Antibodies against Taspase, Threonine Aspartase, 1 Interaction Partners

Mouse (Murine) Taspase, Threonine Aspartase, 1 (TASP1) interaction partners

  1. Upon loss of taspase1, MLL1 association with chromatin is markedly increased due to the stabilization of its unprocessed version, and this stabilization of the uncleaved MLL1 can result in the displacement of MLL chimeras from chromatin in leukemic cells

  2. Taspase1 deficiency disrupts the expression of cyclins and proliferation of HER2+ breast cancer cells.

  3. TFIIA is the principal TASP1 substrate that orchestrates craniofacial morphogenesis.

  4. Taspase1 cleaves a ubiquitously expressed GTF (TFIIA) to enable tissue-specific (testis) transcription, meeting the demand for sophisticated regulation of distinct subsets of genes in higher organisms.

  5. TASP1, EPS15R, and PRPF3 expression were significantly induced in HCCs of transgenic EGF2B mice as was P2 promoter-driven HNF4alpha

  6. This paper describes the quintessential function of Taspase1 in orchestrating cell cycle progression.

Human Taspase, Threonine Aspartase, 1 (TASP1) interaction partners

  1. Proteolytic processing of TFIIA by Taspase1 was found to mask evolutionary conserved nuclear export signal, thereby promoting nuclear localization and transcriptional activation of TFIIA target genes, such as CDKN2A.

  2. Studies indicate that threonine Aspartase1 (Taspase1) is overexpressed in numerous liquid and solid malignancies and was characterized as a 'non-oncogene addiction' protease.

  3. simultaneous expression of the leukemogenic AF4-MLL and dnTASP1 causes the disappearance of the leukemogenic oncoprotein, because the uncleaved AF4-MLL protein (328 kDa) is subject to proteasomal degradation.

  4. Our results provide first evidence that Taspase1 processing affects TFIIA regulation of TFIID and suggest that Taspase1 processing of TFIIA is required to establish INR-selective core promoter activity in the presence of NC2.

  5. inefficient heterodimerization appears to be the mechanism by which inactive Taspase1 variants fail to inhibit wild type Taspase1's activity in trans.

  6. Taspase1 appears to exploit the nuclear export activity of importin-alpha/nucleophosmin to gain transient access to the cytoplasm required to also cleave its cytoplasmic substrates.

  7. Cell-based analysis of structure-function activity of threonine aspartase 1.

  8. Taspase1 is overexpressed in primary human cancers, and deficiency of Taspase1 in cancer cells not only disrupts proliferation but also enhances apoptosis.

  9. purification and cloning of threonine aspartase 1 responsible for cleaving MLL; RNAi-mediated knockdown of Taspase1 results in the appearance of unprocessed MLL and the loss of proper HOX gene expression

  10. Transfected taspase 1 enhances cleavage of TFIIA, and RNA interference knockdown of endogenous taspase 1 diminishes cleavage of TFIIA in vivo.

  11. TASP1, EPS15R, and PRPF3 expression were significantly induced in HCCs of transgenic EGF2B mice as was P2 promoter-driven HNF4alpha

Taspase, Threonine Aspartase, 1 (TASP1) Antigen Profile

Protein Summary

This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene names and symbols associated with TASP1

  • taspase, threonine aspartase 1 (Tasp1) antibody
  • taspase 1 (Tasp1) antibody
  • taspase 1 (TASP1) antibody
  • 4930485D02Rik antibody
  • AW986064 antibody
  • C20orf13 antibody
  • dJ585I14.2 antibody
  • RGD1308591 antibody

Protein level used designations for TASP1

taspase-1 , threonine aspartase 1 , taspase 1

GENE ID SPECIES
75812 Mus musculus
311468 Rattus norvegicus
55617 Homo sapiens
Selected quality suppliers for anti-Taspase, Threonine Aspartase, 1 (TASP1) Antibodies
Did you look for something else?