anti-Testis Derived Transcript (3 LIM Domains) (TES) Antibodies

Cancer-associated chromosomal changes often involve regions containing fragile sites. Additionally we are shipping Testis Derived Transcript (3 LIM Domains) Proteins (27) and Testis Derived Transcript (3 LIM Domains) Kits (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TES 26136 Q9UGI8
TES 21753  
TES 500040 Q2LAP6
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Top anti-Testis Derived Transcript (3 LIM Domains) Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, IHC, WB Immunofluorescence of monoclonal antibody to TES on HeLa cell (antibody concentration 10 µg/mL).  Western Blot analysis of TES expression in transfected 293T cell line by TES monoclonal antibody (M01), clone 1G11-B7. Lane 1: TES transfected lysate(48 KDa). Lane 2: Non-transfected lysate. 100 μg Log in to see 8 to 11 Days
$527.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Testin Antibody  - Staining of human endometrium shows moderate cytoplasmic positivity in glandular cells. Western Blot: Testin Antibody  230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-575 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-TES / Testin antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml. 50 μg Log in to see 11 to 14 Days
$727.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB Western Blot: Testin Antibody  - Analysis in human cell line EFO-21. Immunocytochemistry/Immunofluorescence: Testin Antibody  - Staining of human cell line SiHa shows positivity in cytoplasm and focal adhesion sites. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated WB Western blot analysis in K562 cell line lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to TES on formalin-fixed paraffin-embedded human tonsil tissue. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to TES on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using TES antibody (ABIN5972642) at 1/1000 dilution. 100 μL Log in to see 11 to 16 Days
$412.19
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (72.42 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details

Top referenced anti-Testis Derived Transcript (3 LIM Domains) Antibodies

  1. Human Polyclonal TES Primary Antibody for WB - ABIN1881876 : Qiu, Zhu, Yuan, Yan, Yang, Kong: Frequent hypermethylation and loss of heterozygosity of the testis derived transcript gene in ovarian cancer. in Cancer science 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal TES Primary Antibody for ICC, IF - ABIN4358534 : Danielsson, Wiking, Mahdessian, Skogs, Ait Blal, Hjelmare, Stadler, Uhlén, Lundberg: RNA deep sequencing as a tool for selection of cell lines for systematic subcellular localization of all human proteins. in Journal of proteome research 2013 (PubMed)

More Antibodies against Testis Derived Transcript (3 LIM Domains) Interaction Partners

Human Testis Derived Transcript (3 LIM Domains) (TES) interaction partners

  1. validated two new TES cocomplex partners: TGFB1I1 and a short form of the glucocorticoid receptor. TES and TGFB1I1 are shown to oppositely affect cell spreading providing biological validity for their copresence in complexes since they act in similar processes

  2. these data indicate that TES functions as a necessary suppressor of colorectal cancer progression by activating p38-MAPK signaling pathways.

  3. testin region (amino acids 52-233) harbouring the PET domain interacts with the C-terminal LIM1-2 domains

  4. Testin plays an important role in the development and progression of non-small cell lung cancer. Testin is a tumor suppressor.

  5. VASP, zyxin and TES are tension-dependent members of focal adherens junctions independent of the alpha-catenin-vinculin module.

  6. we confirm that the TES promoter is unmethylated in normal adult and fetal tissues. Re-expression of TESTIN protein in acute lymphoblastic leukemia cells using expression plasmid transfection results in rapid cell death or cell cycle arrest.

  7. Loss of TES gene expression is associated with nasopharyngeal carcinoma.

  8. findings suggest that the TES gene is a novel tumor suppressor gene

  9. TESTIN was hypermethylated in 43.7% endometrial cancer tissues (p < 0.001). Moreover, TESTIN hypermethylation was significantly correlated with advanced tumor stage, deep myometrial invasion and lymphatic node metastasis.

  10. Downregulation of TES was associated with breast cancer.

  11. TESTIN was commonly downregulated in human endometrial carcinoma and was associated with poor prognostic markers.

  12. A further significant correlation was observed between TES downregulation and the luminal B subtype independent of survivin expression.

  13. TES, as a valuable marker of breast cancer prognosis, plays an important role in the development and progression of breast cancer. TES may be an effective novel target in breast cancer prevention and treatment.

  14. Low TES gene expression is associated with coronary artery disease.

  15. Alterations of TES mRNA level may predict the location of metastasis. CAV1 possibly affect the cancer cell invasion

  16. These results suggest an interplay between the CaR and testin in the regulation of CaR-mediated Rho signalling with possible effects on the cytoskeleton.

  17. Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A.

  18. data implicate TES methylation in ALL and provide additional evidence for the involvement of LIM domain proteins in leukaemogenesis

  19. results support the role of TES as a TSG in gastric carcinogenesis and that TES is inactivated primarily by LOH and CpG island methylation

  20. The expression level of TES is significantly down-regulated in primary gastric cancer.

Xenopus laevis Testis Derived Transcript (3 LIM Domains) (TES) interaction partners

  1. Prickle and tes act together to control axial elongation.

Mouse (Murine) Testis Derived Transcript (3 LIM Domains) (TES) interaction partners

  1. zyxin influences focal adhesion dynamics, that it recruits Tes and that this interaction is functional in regulating cell spreading.

  2. Testin is a mammalian gene involved in coordinated orientation of hair cells in the inner ear and in the development of the female reproductive tract.

  3. TES acts as a tumor suppressor in an established model of carcinogen-induced gastric cancer

Testis Derived Transcript (3 LIM Domains) (TES) Antigen Profile

Protein Summary

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.

Gene names and symbols associated with TES

  • testin LIM domain protein (TES) antibody
  • testin LIM domain protein L homeolog (tes.L) antibody
  • testis derived transcript (3 LIM domains) (tes) antibody
  • testin LIM domain protein (tes) antibody
  • testis derived transcript (3 LIM domains) (TES) antibody
  • testis derived transcript (Tes) antibody
  • testin LIM domain protein (Tes) antibody
  • D6Ertd352e antibody
  • DKFZp469E2320 antibody
  • TES antibody
  • Tes1 antibody
  • Tes2 antibody
  • tess antibody
  • tess-2 antibody
  • Testin antibody
  • testin2 antibody
  • xtes antibody
  • zgc:92091 antibody

Protein level used designations for TES

testin , xtes , testis derived transcript (3 LIM domains) , TES1/TES2 , testin 2 , Testin-like protein , testis derived transcript , LOW QUALITY PROTEIN: testin

GENE ID SPECIES
26136 Homo sapiens
380398 Xenopus laevis
395332 Gallus gallus
403032 Danio rerio
448383 Xenopus (Silurana) tropicalis
463669 Pan troglodytes
475293 Canis lupus familiaris
534965 Bos taurus
706879 Macaca mulatta
780949 Monodelphis domestica
100126573 Ovis aries
100126668 Papio anubis
100137158 Nomascus leucogenys
100173774 Pongo abelii
21753 Mus musculus
100125376 Sus scrofa
100126564 Oryctolagus cuniculus
100137197 Felis catus
100071093 Equus caballus
500040 Rattus norvegicus
100407335 Callithrix jacchus
100718235 Cavia porcellus
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