Thrombospondin 4 Proteins (THBS4)

The protein encoded by THBS4 belongs to the thrombospondin protein family. Additionally we are shipping Thrombospondin 4 Antibodies (50) and Thrombospondin 4 Kits (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
THBS4 29220  
THBS4 7060 P35443
THBS4 21828 Q9Z1T2
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Top Thrombospondin 4 Proteins at

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 15 to 18 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 11 to 18 Days

THBS4 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , ,
, ,
Mouse (Murine)

More Proteins for Thrombospondin 4 (THBS4) Interaction Partners

Human Thrombospondin 4 (THBS4) interaction partners

  1. Findings indicate that loss of miR (show MLXIP Proteins)-142 results in the over-expression of THBS4, which enhances HCC (show FAM126A Proteins) migration and vascular invasion.

  2. the present study demonstrates that THBS4 and lncRNA-THBS4-003 serve a significant role in PCa (show FLVCR1 Proteins) proliferation and migration via the MMP-9 (show MMP9 Proteins) and p38 MAPK (show MAPK14 Proteins) signaling pathway.

  3. THBS2 (show THBS2 Proteins) and THBS4 mRNA are overexpressed in gastric cancer in a Southeast Chinese population.

  4. The THBS4 A387P polymorphism was associated with coronary artery disease in American population.

  5. Tsp4 functions as an ECM (show MMRN1 Proteins) scaffold at myotendinous (show TNC Proteins) junctions, with potential therapeutic uses in tendon strengthening and repair

  6. THBS4 expression in breast cancer-associated extracellular matrix contributes to the activated stromal response exhibited during tumour progression

  7. the balancing selection target in THBS4 is likely represented by one or more variants that regulate tissue-specific and sex-specific gene expression

  8. The results of thid study suggested that injury-induced spinal TSP4 may contribute to spinal presynaptic hypersensitivity and neuropathic pain states.

  9. genetic polymorphism predicts cardiovascular risk in postinfarction patients with high HDL (show HSD11B1 Proteins) cholesterol and C-reactive protein (show CRP Proteins) levels

  10. Identify THBS4 as a powerful marker for diffuse-type gastric adenocarcinomas and to provide an initial characterization of its expression in the course of this disease.

Mouse (Murine) Thrombospondin 4 (THBS4) interaction partners

  1. Loss of the Thbs4 gene causes spontaneous dystrophic changes with aging and accelerates disease in 2 mouse models of muscular dystrophy, while overexpression of mouse Thbs4 is protective and mitigates dystrophic disease.

  2. TSP-4 plays a role in angiotensin II induced hypertension, affecting cardiac hypertrophy, aortic aneurysm formation, as well as endothelial-dependent relaxation in resistance arteries.

  3. This study demonstrated THAT elevated TSP4 after peripheral nerve injury may contribute to hypersensitivity of peripheral sensory systems by decreasing HVA and increasing LVA in DRG neurons by targeting the alpha2delta1 calcium subunit.

  4. Absence of Thbs4 abrogated adipose tissue inflammation and neointimal formation supporting the potential for inhibition of Thbs4 to prevent inflammatory vascular pathologies/diseases such as restenosis.

  5. present studies on the cardiac function of KLF6 (show KLF6 Proteins) show a new mechanism whereby cardiomyocytes regulate cardiac fibrosis through transcriptional control of the extracellular matrix factor thrombospondin 4

  6. these data identify the critical intracellular functional domains of thrombospondin-4, which was formerly thought to have only extracellular functions

  7. TSP-4, an extracellular matrix protein previously associated with tissue remodeling, is now demonstrated to possess proangiogenic activity.

  8. This study demonistrated that Thrombospondin 4 deficiency in mouse impairs neuronal migration in the early postnatal and adult brain.

  9. thrombospondin-4 is downregulated by curcumin-induced oxidized low-density lipoprotein in mouse macrophages

  10. findings have important implications for post-injury applications of endogenous and transplanted neural stem cells in the therapeutic setting, as well as disease states where Thbs (show THBS1 Proteins) family members have important roles

Cow (Bovine) Thrombospondin 4 (THBS4) interaction partners

  1. Thrombospondin-4 widely distributed in bovine eye where it may play role in functions of basement membranes in various tissues. Abundant in trabecular and uveo-scleral pathways. May play role in regulation of aqueous outflow resistance.

  2. thrombospondin-4 C-terminal peptide has a role in stimulating erythroid cell proliferation

Thrombospondin 4 (THBS4) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. Studies of the rat counterpart suggest that this protein may be involved in local signaling in the developing and adult nervous system.

Gene names and symbols associated with Thrombospondin 4 Proteins (THBS4)

  • thrombospondin 4 S homeolog (thbs4.S)
  • thrombospondin 4 (Thbs4)
  • thrombospondin 4 (THBS4)
  • MGC79977 protein
  • TSP-4 protein
  • TSP4 protein

Protein level used designations for Thrombospondin 4 Proteins (THBS4)

thrombospondin 4 , thrombospondin-4

446985 Xenopus laevis
29220 Rattus norvegicus
7060 Homo sapiens
21828 Mus musculus
541281 Bos taurus
396306 Gallus gallus
100357137 Oryctolagus cuniculus
100720036 Cavia porcellus
100513005 Sus scrofa
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