anti-Thymus High Mobility Group Box Protein (TOX) Antibodies

The protein encoded by TOX contains a HMG box DNA binding domain. Additionally we are shipping TOX Proteins (4) and TOX Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TOX 9760 O94900
TOX 252838 Q66JW3
TOX 362481  
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Top anti-TOX Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TOX Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate TOX is supported by BioGPS gene expression data to be expressed in Jurkat WB Suggested Anti-TOX  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate  TOX is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  TOX  Sample Type:  Ovary Tumor lysates  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg 11 to 14 Days
$616.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of TOX in human colon tissue with TOX polyclonal antibody  at (1) 1 and (2) 2 ug/mL. 100 μg 11 to 12 Days
$356.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of TOX in human colon tissue lysate with TOX antibody at (A) 1 and (B) 2 µg/mL. 0.1 mg 2 to 3 Days
$360.00
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IHC, WB 100 μg 2 to 3 Days
$258.46
Details
Human Rabbit Un-conjugated IF/ICC, WB Immunofluorescence analysis of U2OS cells using TOX antibody (ABIN5974241). 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated IF Immunofluorescence analysis of U2OS cells using TOX antibody. 200 μL 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated IF, IHC, WB Immunofluorescence analysis of U20S cell using TOX antibody. Immunofluorescence analysis of U2OS cells using TOX antibody (ABIN2560492). 100 μL 11 to 13 Days
$366.77
Details

Top referenced anti-TOX Antibodies

  1. Human Polyclonal TOX Primary Antibody for IHC, IHC (p) - ABIN4359425 : McGirt, Adams, Baerenwald, Zwerner, Zic, Eischen: miR-223 regulates cell growth and targets proto-oncogenes in mycosis fungoides/cutaneous T-cell lymphoma. in The Journal of investigative dermatology 2014 (PubMed)

More Antibodies against TOX Interaction Partners

Human Thymus High Mobility Group Box Protein (TOX) interaction partners

  1. hypothesis that TOX-induced exhaustion program serves to prevent the overstimulation of T cells and activation-induced cell death in settings of chronic antigen stimulation such as cancer

  2. TOX is a critical factor for the normal progression of T cell dysfunction and the maintenance of exhausted T cells during chronic infection, and provide a link between the suppression of effector function intrinsic to CD8 T cells and protection against immunopathology

  3. Suggest that F nucleatum may suppress antitumor immune responses by decreasing CD4(+) T-cell density and TOX expression in the progression of colorectal cancer.

  4. TOX gene SNP rs11777927 was associated with antipsychotic-induced weight gain.

  5. TOX is an HMG box-containing protein that has important roles in T-ALL initiation and maintenance. TOX inhibits the recruitment of KU70/KU80 to DNA breaks, thereby inhibiting NHEJ repair. Thus, TOX is likely a dominant oncogenic driver in a large fraction of human T-ALL and enhances genomic instability

  6. TOX expression is insufficient for diagnosis of cutaneous T-cell lymphoma

  7. data suggest that GATA3 regulates TOX, revealing insight into TOX regulation

  8. The expression of Sezary signature genes: FCRL3, Tox, and miR-214, was significantly higher in samples from Sezary syndrome patients with CD164 expressing CD4(+) T cells.

  9. Significant associations between single nucleotide polymorphisms in TOX, CDKN2A/B and type 2 diabetes meillitus.

  10. The SLC2A9 (rs7660895) and TOX (rs11777927) gene polymorphisms may be associated with formation of intracranial aneurysms, and rs7660895 may be associated with intracranial aneurysms rupture.

  11. TOX may be a specific marker for tumour cells in some types of cutaneous lymphoma.

  12. High TOX transcript levels correlate with increased cutaneous T-cell lymphoma.

  13. SNP rs2726600 is located in a transcription-factor binding site in the 3' region of TOX.

  14. Compared with TOX4, expression of TOX1, TOX2 and TOX3 in normal lung was 25, 44, and 88%lower, respectively, supporting the premise that reduced promoter activity confers increased susceptibility to methylation during lung carcinogenesis.

  15. results suggest that TOX is required for IL-15-mediated natural killer (NK) cell differentiation and affected expression of T-bet that plays critical roles in NK differentiation and maturation

  16. expression of the HMG box protein TOX is sufficient to induce changes in coreceptor gene expression associated with beta-selection, including CD8 gene demethylation

Mouse (Murine) Thymus High Mobility Group Box Protein (TOX) interaction partners

  1. identification of the HMG-box transcription factor TOX as a central regulator of Tex cells in mice

  2. hypothesis that TOX-induced exhaustion program serves to prevent the overstimulation of T cells and activation-induced cell death in settings of chronic antigen stimulation such as cancer

  3. TOX is a critical factor for the normal progression of T cell dysfunction and the maintenance of exhausted T cells during chronic infection, and provide a link between the suppression of effector function intrinsic to CD8 T cells and protection against immunopathology

  4. Results identify TOX as a transcriptional regulator of tissue-destructive CTLs in autoimmunity.

  5. is required for generation of a common innate lymphoid cell progenitor

  6. TOX is necessary to establish the CD4(+) T cell lineage gene program.

  7. TOX has been identified as an essential regulator of the development of multiple facets of the adaptive immune system and have added another commonality to the developmental pathways of Natural killer cells and lymphoid tissue inducer cells.

TOX Antigen Profile

Protein Summary

The protein encoded by this gene contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.

Gene names and symbols associated with TOX

  • thymocyte selection associated high mobility group box (TOX) antibody
  • thymocyte selection-associated high mobility group box (Tox) antibody
  • 1700007F02Rik antibody
  • TOX1 antibody

Protein level used designations for TOX

thymocyte selection-associated high mobility group box protein TOX , thymus high mobility group box protein TOX , thymocyte selection-associated HMG box

GENE ID SPECIES
421138 Gallus gallus
9760 Homo sapiens
486964 Canis lupus familiaris
525888 Bos taurus
252838 Mus musculus
362481 Rattus norvegicus
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