TOX antibody (N-Term)

Catalog No. ABIN2778079

The Rabbit Polyclonal anti-TOX antibody (ABIN2778079) specifically detects TOX in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Rabbit samples.

Quick Overview for TOX antibody (N-Term) (ABIN2778079)

Target: TOX (Thymus High Mobility Group Box Protein (TOX))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TOX Antibody

Binding Specificity: N-Term

Purpose: TOX Antibody - N-terminal region

Sequence: CLDPYYCNKF DGENMYMSMT EPSQDYVPAS QSYPGPSLES EDFNIPPITP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against TOX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TOX

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113859

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TOX

Target: TOX (Thymus High Mobility Group Box Protein (TOX))

Alternative Name: TOX

Background:

Background Information: Some high-mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.Some high-mobility group (HMG) box proteins (e.g., LEF1, MIM 153245) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1, MIM 163905) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.[supplied by OMIM].

Gene Name: Thymocyte selection-associated high mobility group box

Alternative Symbols: TOX1

Protein Name: Thymocyte selection-associated high mobility group box protein TOX

Molecular Weight: 58kDa

Gene ID: 9760

NCBI Accession: NP_055544

UniProt: O94900