TFPI Proteins

Protein Summary

This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.

Gene names and symbols associated with TFPI

• tissue factor pathway inhibitor (TFPI) antibody
• tissue factor pathway inhibitor (Tfpi) antibody
• tissue factor pathway inhibitor a (tfpia) antibody

• A630013F22Rik antibody
• AW552122 antibody
• EPI antibody
• LACI antibody
• si:dz44f8.1 antibody
• Show all synonym aliases
• TFI antibody
• TFPI antibody
• TFPI1 antibody
• tfpib antibody
• wu:fb92g01 antibody
• zgc:152844 antibody
• zgc:158592 antibody

Protein level used designations for TFPI

anti-convertin , extrinsic pathway inhibitor , tissue factor pathway inhibitor , lipoprotein-associated coagulation inhibitor , EPI , LACI , uncharacterized protein LOC100155068 , LOW QUALITY PROTEIN: tissue factor pathway inhibitor , coagulation inhibitor , lipoprotein-associated , tissue factor pathway inhibitor b , tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)