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Sarcomere assembly is regulated by the muscle protein titin. Additionally we are shipping TCAP Antibodies (37) and many more products for this protein.
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Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
, 19 kDa sarcomeric protein
, limb girdle muscular dystrophy 2G (autosomal recessive)
, titin cap protein
, titin-cap protein