Protein Summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Gene names and symbols associated with tPSA

• kallikrein related peptidase 3 (KLK3) antibody
• kallikrein 1-related peptidase C3 (Klk1c3) antibody

• APS antibody
• hK3 antibody
• Klk1c10l2 antibody
• KLK2A1 antibody
• KLK3 antibody
• Show all synonym aliases
• PSA antibody
• rGK-3 antibody
• RSGK-50 antibody
• RSKG-50 antibody

Protein level used designations for tPSA

P-30 antigen , gamma-seminoprotein , kallikrein-3 , prostate specific antigen , prostate-specific antigen , semenogelase , seminin , S1 kallikrein , glandular kallikrein-3, submandibular , kallikrein 1-related peptidase c10-like 2 , kallikrein 3 , submaxillary gland S1 kallikrein , tissue kallikrein