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TCEB3 encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. Additionally we are shipping TCEB3 Antibodies (98) and TCEB3 Proteins (7) and many more products for this protein.
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associates with transcriptionally active puff sites within Drosophila polytene chromosomes and exhibits many of the expected biochemical and cytological properties consistent with a Pol II-associated elongation factor
RNA polymerase II elongation factor, Elongin A, has an essential role in the regulation of heat shock gene expression
Polycomb repressive complex 2 modulates transcription of a subset of low expression target genes in part via methylation of EloA.
Elongin A transcription elongation activity, but not its ubiquitination activity, is most important for its function in induction of transcription of ATF3 and p21.
Elongin A transcriptional elongation activity, but not its E3 ubiquitin ligase activity, is critical for these functions.
a linkage between Elongin A function and cell cycle progression
The authors that both the ubiquitylation and proteasomal degradation of the largest subunit of pol II (Rpb1) following UV-irradiation are significantly suppressed in Elongin A-deficient cells.
the Elongin A ubiquitin ligase and the CSB protein function together in a common pathway in response to Pol II stalling and DNA damage
TCEB3C is a putative tumor suppressor gene of small intestinal neuroendocrine tumors
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
, elongin A
, transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
, transcription elongation factor B polypeptide 3-like
, Elongin A
, RNA polymerase II transcription factor SIII subunit A1
, SIII p110
, elongin 110 kDa subunit
, transcription elongation factor B polypeptide 3
, RNA polymerase II transcription factor SIII subunit A
, RNA polymerase II transcription factor elongin subunit A (110 kDa)
, transcription elongation factor B alpha subunit