Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) Proteins (TFAP2E)

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. Additionally we are shipping TFAP2E Antibodies (14) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat TFAP2E TFAP2E 313596  
TFAP2E 339488 Q6VUC0
TFAP2E 332937 Q6VUP9
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Top TFAP2E Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$338.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$3,213.83
Details

TFAP2E Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) (TFAP2E) Interaction Partners

Zebrafish Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) (TFAP2E) interaction partners

  1. These findings reveal that Tfap2 (show TFAP2A Proteins) activity, mediated redundantly by Tfap2a (show TFAP2A Proteins) and Tfap2e, promotes melanophore differentiation in parallel with Mitf (show MITF Proteins) by an effector other than Kit.

Human Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) (TFAP2E) interaction partners

  1. Results showed that lower expression levels of TFAP2E are significantly associated with a shorter survival of patients with neuroblastoma (show ARHGEF16 Proteins) indicating that TFAP2E acts as a tumor suppressor of neuroblastoma (show ARHGEF16 Proteins).

  2. Hypermethylation of TFAP2E was associated with lack of response to fluorouracil-based chemotherapy, indicating that it might be a potential predictor of treatment response in patients with gastric cancer.

  3. AP-2E was frequently hypermethylated in tumors from patients with colorectal cancer

  4. AP-2epsilon indirectly interacts with the core promoter of COL2A1 (show COL2A1 Proteins) and subsequently inhibits its transcriptional activity, thus modulating cartilage development.

  5. TFAP2E hypermethylation is associated with clinical nonresponsiveness to chemotherapy in colorectal cancer.

  6. These findings reveal that Tfap2 (show TFAP2A Proteins) activity, mediated redundantly by Tfap2a (show TFAP2A Proteins) and Tfap2e, promotes melanophore differentiation in parallel with Mitf (show MITF Proteins) by an effector other than Kit.

Xenopus laevis Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) (TFAP2E) interaction partners

  1. Report of the expression and function of Tfap2e in developing Xenopus laevis; propose that Tfap2e is a novel player in the gene regulatory network controlling neural crest specification in Xenopus downstream of Pax3 (show PAX3 Proteins) and Zic1

Mouse (Murine) Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) (TFAP2E) interaction partners

  1. We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 (show MMP13 Proteins) expression and activity.

  2. cloning and characterization; AP-2 epsilon is expressed most prominently in the mitral cell layer of the developing olfactory bulb; it is able to activate transcription in a binding site-dependent manner

  3. AP-2 epsilon is important for the development of the olfactory system.

TFAP2E Protein Profile

Protein Summary

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions (By similarity).

Gene names and symbols associated with TFAP2E

  • transcription factor AP-2 epsilon (tfap2e)
  • transcription factor AP-2 epsilon (Tfap2e)
  • transcription factor AP-2 epsilon (TFAP2E)
  • transcription factor AP-2 epsilon L homeolog (tfap2e.L)
  • transcription factor AP-2, epsilon (Tfap2e)
  • AI505200 protein
  • AP-2e protein
  • AP2E protein
  • RGD1563297 protein
  • Tcfap2e protein
  • zgc:65882 protein
  • zgc:77338 protein

Protein level used designations for TFAP2E

AP-2-epsilon , transcription factor AP-2-epsilon , AP2-epsilon , activating enhancer-binding protein 2-epsilon , adaptor-related protein complex 2, epsilon subunit , activating enhancer-binding protein 2 epsilon

GENE ID SPECIES
393794 Danio rerio
313596 Rattus norvegicus
339488 Homo sapiens
525824 Bos taurus
735028 Xenopus laevis
332937 Mus musculus
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