Transcription Factor CP2-Like 1 Proteins (TFCP2L1)

Transcriptional suppressor.

list all proteins Gene Name GeneID UniProt
Human TFCP2L1 TFCP2L1 29842 Q9NZI6
Mouse TFCP2L1 TFCP2L1 81879 Q3UNW5
Rat TFCP2L1 TFCP2L1 304741  
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Top TFCP2L1 Proteins at antibodies-online.com

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
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Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$225.40
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
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Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
$3,285.33
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More Proteins for Transcription Factor CP2-Like 1 (TFCP2L1) Interaction Partners

Human Transcription Factor CP2-Like 1 (TFCP2L1) interaction partners

  1. Study show that CRTR-1 is generally an activator of transcription (show STAT1 Proteins) and that it modulates the activity of other family members, CP2 (show CP Proteins), NF2d9 (show UBP1 Proteins) and altNF2d9, in a cell specific manner.

  2. LBP-1b (show UBP1 Proteins) is an important SF1 (show NR5A1 Proteins)-independent transcriptional activator stimulating P450scc (show CYP11A1 Proteins) expression in human placental JEG-3 cells, whereas LBP-9 modulates the action of LBP-1b (show UBP1 Proteins), exerting both positive and negative effects

  3. LBP-1b (show UBP1 Proteins) and LBP-9 both stimulate LBP-32/MGR (show GRHL1 Proteins) promoter activity.

Mouse (Murine) Transcription Factor CP2-Like 1 (TFCP2L1) interaction partners

  1. Thus, Tfcp2l1 is a critical regulator of intercalated cell-principal cell patterning in kidney collecting ducts, acting cell-autonomously in intercalated cells, and non-cell-autonomously in principal cells.

  2. TFCP2L1 depends on its N-terminus and CP2-like domain to maintain the undifferentiated state of mouse embryonic stem cells.

  3. we found that TFCP2L1 is hexamerized in solution via the C-terminal SAM (show TTN Proteins)-like domain. We also found that homo-oligomerization of SAM (show TTN Proteins)-like domain is dependent on the concentration of the proteins.

  4. study therefore establishes the pivotal role of Klf2 (show KLF2 Proteins) and Tfcp2l1 in mediating ESC self-renewal promoted by Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling.

  5. Tfcp2l1 is the principal bridge between LIF (show LIF Proteins)/Stat3 (show STAT3 Proteins) input and the transcription factor core of naive pluripotency.

  6. Tfcp2l1 is at the intersection of LIF (show LIF Proteins)- and 2i-mediated self-renewal pathways and plays a critical role in maintaining embryonic stem cell identity.

  7. Cp2l1 expression is required for normal duct development in both the salivary gland and kidney.

TFCP2L1 Protein Profile

Protein Summary

Transcriptional suppressor. May suppress UBP1-mediated transcriptional activation. Required for normal duct development in the salivary gland and kidney.

Gene names and symbols associated with TFCP2L1

  • transcription factor CP2 like 1 (TFCP2L1)
  • transcription factor CP2-like protein 1 (LOC100078599)
  • transcription factor CP2-like 1 (Tfcp2l1)
  • transcription factor CP2-like 1 (tfcp2l1)
  • transcription factor CP2 like 1 (tfcp2l1)
  • transcription factor CP2-like 1 L homeolog (tfcp2l1.L)
  • transcription factor CP2 like 1 (Tfcp2l1)
  • 1810030F05Rik protein
  • 4932442M07Rik protein
  • AA575098 protein
  • Cp2l1 protein
  • Crtr-1 protein
  • crtr1 protein
  • D930018N21Rik protein
  • lbp-9 protein
  • lbp9 protein
  • Tcfcp2l1 protein
  • tfcp2l1 protein
  • tfcp2l1a protein
  • zgc:91796 protein

Protein level used designations for TFCP2L1

CP2-related transcriptional repressor 1 , CRTR-1 , transcription factor CP2-like protein 1 , transcription factor LBP-9 , transcription factor CP2-like 1 , Tcfcp2-related transcriptional repressor 1 , transcription repressor CRTR-1 , LBP-9 , transcription factor CP2-like protein 1-like , LBP protein; likely ortholog of mouse CRTR-1 , transcription factor CP2-like 1 a

GENE ID SPECIES
29842 Homo sapiens
100078599 Ornithorhynchus anatinus
81879 Mus musculus
304741 Rattus norvegicus
424238 Gallus gallus
431761 Danio rerio
518436 Bos taurus
610193 Canis lupus familiaris
750129 Pan troglodytes
100172521 Pongo abelii
100563123 Anolis carolinensis
549628 Xenopus (Silurana) tropicalis
696479 Macaca mulatta
100010272 Monodelphis domestica
100414646 Callithrix jacchus
100472615 Ailuropoda melanoleuca
100519339 Sus scrofa
100545526 Meleagris gallopavo
380069 Xenopus laevis
100720387 Cavia porcellus
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