anti-Transgelin 2 (TAGLN2) Antibodies

The protein encoded by TAGLN2 is a homolog of the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. Additionally we are shipping Transgelin 2 Kits (16) and Transgelin 2 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TAGLN2 21346 Q9WVA4
TAGLN2 304983 Q5XFX0
TAGLN2 8407 P37802
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Top anti-Transgelin 2 Antibodies at antibodies-online.com

Showing 10 out of 72 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB TAGLN2 Antibody (C-term) (ABIN657984) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the TAGLN2 antibody detected the TAGLN2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: transgelin 2 Antibody  - Analysis in human cell line A-431. Immunocytochemistry/Immunofluorescence: transgelin 2 Antibody  - Staining of human cell line U-2 OS shows positivity in cytoplasm and actin filaments. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ICC, IF, WB Immunocytochemistry/Immunofluorescence: transgelin 2 Antibody  - A549 cells were fixed in ice-cold MeOH for 5 min. Green: Transgelin 2 protein stained by Transgelin 2 antibody  diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um. Immunocytochemistry/Immunofluorescence: transgelin 2 Antibody  - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Transgelin 2 protein stained by Transgelin 2 antibody  diluted at 1:500. Red: phalloidin, a cytoskeleton marker, stained by phalloidin (invitrogen, A12380) diluted at 1:200. Blue: Hoechst 33342 staining. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of human heart tissue, using Transgelin 2 antibody. Western blot analysis of extracts from rat brain, using Transgelin 2 antibody. Lane 1 was treated with the blocking peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human 293T Cells; Lane2: Porcine Heart Tissue; Lane3: Porcine Kidney Tissue. Figure. Western Blot; Sample: Recombinant TAGLN2, Human. 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded muscle of mouse embryo labeled with Anti-TAGL2 Polyclonal Antibody, Unconjugated (ABIN682423) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated IF/ICC, WB Western blot analysis of extracts of various cell lines, using TAGLN2 antibody (ABIN5974091) at 1/1000 dilution. Immunofluorescence analysis of MCF-7 cells using TAGLN2 antibody (ABIN5974091). Blue: DAPI for nuclear staining. 100 μL Log in to see 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of extracts of various cell lines, using TAGLN2 antibody. Immunofluorescence analysis of MCF-7 cells using TAGLN2 antibody. 200 μL Log in to see 12 to 14 Days
$438.90
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using TAGLN2 antibody. Immunofluorescence analysis of MCF7 cell using TAGLN2 antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 11 to 13 Days
$366.77
Details

Top referenced anti-Transgelin 2 Antibodies

  1. Human Polyclonal TAGLN2 Primary Antibody for ICC, IF - ABIN4361997 : Yoshino, Chiyomaru, Enokida, Kawakami, Tatarano, Nishiyama, Nohata, Seki, Nakagawa: The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. in British journal of cancer 2011 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Transgelin 2 Interaction Partners

Mouse (Murine) Transgelin 2 (TAGLN2) interaction partners

  1. These results revealed a novel function of TAGLN2 as a molecular armament required for host defense.

  2. transgelin-2 may also be involved in IS stability in B-cells, thereby influencing T-cell function

  3. All these results indicated a crucial role for Tagln2 in TECs for tumor development and metastasis.

  4. A novel function of TAGLN2 in enhancing T cell responses by controlling actin stability at the immunological synapse.

  5. The results indicate that miR-133b may play important roles in the growth and maturation of oocytes by regulating its potential target, TAGLN2, at both transcription and translation levels.

  6. we demonstrate that methylation of SM22alpha promoter is an important event in vascular smooth muscle cell calcification and that high phosphate induces this epigenetic modification.

  7. data demonstrate that SM22beta is a novel actin-associated protein with a unique cell lineage-restricted pattern of expression

Human Transgelin 2 (TAGLN2) interaction partners

  1. Authors found transgelin-2 expression was induced by KRAS mutation. In the case of KRAS mutation, ERK2 interacted with 29-31 amino acids of transgelin-2 and subsequently phosphorylated the S145 residue of transgelin-2.

  2. Study provides important evidence that hypoxia-inducible TAGLN2 is involved in the selection of cancer cells with enhanced EMT properties to overcome the detrimental environment of cancer cells as gamma radiation.

  3. Results show that Increased expression of TAGLN2 is associated with increasing tumor grade in glioma and poor patient survival. Knockdown experiments highlighted the function of TAGLN2 in promoting glioma cell invasion, the EMT phenotype, and tumor growth.

  4. Our data support a novel mechanism in diabetes-associated PDAC by which transgelin-2 mediates proliferation of PDAC cells upon insulin stimulation.

  5. Results suggest that TAGLN2 might regulate activation and migration of B-cells, in particular, the entry of activated B-cells into the follicle.

  6. we reviewed the basic characteristics and function of Transgelin-2 and its biological role in various types of diseases in order to provide the theoretical basis for further research and new perspectives on cancer development.

  7. Our data demonstrated that TAGLN2 might be an HBx induced positive host factor involved in HBV transcription and replication and HBx related liver fibrosis and tumorigenesis

  8. Transgelin-2 plays functional roles in the progression of cervical squamous cell carcinoma. Suppression of Transgelin-2 may be a new strategy for the treatment of cervical squamous cell carcinoma.

  9. It is a target gene of miR-1.

  10. Salvianolic acid A can reverse the paclitaxel resistance and inhibit the migration and invasion abilities of human breast cancer cells by down-regulating the expression of transgelin 2.

  11. Proteomics result showed TAGLN2 as the most significant overexpression in individual bladder cancer tissues and urine specimens, and thus represents a potential biomarker for noninvasive screening for bladder cancer.

  12. TAGLN2 modulates hypoxia-induced apoptosis via caspase-8 apoptotic pathway. Taken together, our data demonstrated the roles of miR-133a in hypoxia-induced apoptotic and implicate its potential in cardiac dysfunctions therapy.

  13. Transgelin-2, a sequence homolog of transgelin, whose role in the tumor development might be contradictory to the role of transgelin.

  14. PTTG1 and TAGLN2 are highly expressed in human pancreatic cancer, and the positive expression of PTTG1 is associated with the gender of cancer patients, suggesting that it may represent a potential therapeutic target for the treatment of pancreatic cancer

  15. our data propose a novel, oncogene-tumor suppressor interplay, where oncogenic PFTK1 confers HCC cell motility through inactivating the actin-binding motile suppressing function of TAGLN2 via phosphorylation.

  16. Data indicate that TAGLN2 may have an oncogenic function and may be regulated by miR-1, a tumor suppressive miRNA in HNSCC.

  17. in pulmonary adenocarcinoma, overexpression of TAGLN was strictly localized to the tumor-induced reactive myofibroblastic stromal tissue compartment, whereas overexpression of TAGLN2 was exclusively localized to the neoplastic glandular compartment

Transgelin 2 (TAGLN2) Antigen Profile

Protein Summary

The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Transgelin 2 (TAGLN2) Antibodies

  • transgelin 2 (TAGLN2) antibody
  • transgelin 2 S homeolog (tagln2.S) antibody
  • transgelin 2 (tagln2) antibody
  • transgelin 2 (Tagln2) antibody
  • 2700094C18Rik antibody
  • HA1756 antibody
  • MGC53739 antibody
  • MGC75598 antibody
  • Sm22a antibody
  • Sm22B antibody
  • SM22beta antibody

Protein level used designations for anti-Transgelin 2 (TAGLN2) Antibodies

transgelin 2 , SM22-beta , transgelin-2 , SM22-alpha homolog , epididymis tissue protein Li 7e

GENE ID SPECIES
610210 Canis lupus familiaris
380476 Xenopus laevis
394981 Xenopus (Silurana) tropicalis
469546 Pan troglodytes
21346 Mus musculus
304983 Rattus norvegicus
8407 Homo sapiens
282379 Bos taurus
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