anti-Transglutaminase 1, Keratinocyte (TGM1) Antibodies

The protein encoded by TGM1 is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. Additionally we are shipping TGM1 Kits (26) and TGM1 Proteins (19) and many more products for this protein.

Gene Name	GeneID	UniProt
TGM1	60335	P23606
TGM1	7051	P22735
TGM1	21816	Q9JLF6

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Top anti-TGM1 Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No.	Reactivity	Host	Conjugate	Application	Quantity	Supplier	Delivery	Price	Details
ABIN2776952	Cow	Rabbit	Un-conjugated	WB	100 μL	Log in to see	2 to 3 Days	$319.00	Details
ABIN4362054	Human	Rabbit	Un-conjugated	IHC, IHC (p), WB	0.1 mL	Log in to see	10 to 13 Days	$491.63	Details
ABIN463265	Guinea Pig	Rabbit	Un-conjugated	WB	50 μg	Log in to see	11 to 14 Days	$551.83	Details
ABIN1804090	Human	Mouse	Un-conjugated	ICC, IHC, IHC (p), IP, WB	50 μg	Log in to see	11 to 14 Days	$484.00	Details
ABIN3042982	Human	Rabbit	Un-conjugated	WB	100 μg	Log in to see	4 to 6 Days	$240.00	Details
ABIN1860740	Rabbit	Guinea Pig	Un-conjugated	ICC, IHC (fro), IHC (p), ELISA, WB	100 μg	Log in to see	13 to 16 Days	$360.00	Details
ABIN1860736	Human	Rabbit	Un-conjugated	ICC, IHC, WB	100 μg	Log in to see	13 to 16 Days	$332.00	Details
ABIN1860739	Mouse	Rabbit	Un-conjugated	ICC, IHC, WB	100 μg	Log in to see	13 to 16 Days	$342.00	Details
ABIN1860737	Rat	Rabbit	Un-conjugated	ICC, IHC, WB	100 μg	Log in to see	13 to 16 Days	$362.00	Details
ABIN1860738	Dog	Rabbit	Un-conjugated	ICC, IHC, WB	100 μg	Log in to see	13 to 16 Days	$380.00	Details

More product categories related to TGM1 Antibody

More Antibodies against TGM1 Interaction Partners

Cow (Bovine) Transglutaminase 1, Keratinocyte (TGM1) interaction partners

Linkage analysis excluded TGM1 as the cause for ichthyosis (show LBR Antibodies) phenotype.

Human Transglutaminase 1, Keratinocyte (TGM1) interaction partners

We also reveal that TGM1 modulates lung epithelial junction protein expression, suggesting a potentially protective role for hypoxia-induced TGM1 in pulmonary disease.
A novel TGM1 variant c.1085T>G was found in an Emirati family. The mutation causes a nonsynonymous protein change (p.Leu362Arg) that affects a highly conserved residue in the catalytic core domain of the calcium-dependent transglutaminase-1.
that the up-regulation of molecular signatures for antimicrobial and innate defense responses is characteristic of skin with a transglutaminase 1 deficiency.
Seven of 10 probands with a compound heterozygous TGM1 genotype had a mutation at either arginine 307 or 315, providing evidence that mutations at these sites are temperature sensitive and highlighting the importance of these residues in the pathogenesis of bathing suit ichthyosis (show LBR Antibodies)
The results strongly supported the participation of TGM1 in the regulation of gastric cancer development. The authors found evidence that the mechanism of action of TGM1 in regulating gastric cancer cell might involve the Wnt (show WNT2 Antibodies) signaling pathway, as loss of TGM1 expression in gastric cancer cells led to a significant suppression of Wnt (show WNT2 Antibodies) signaling activities.
we identified three novel mutations and one reported mutation in the TGM1 and ABCA12 (show ABCA12 Antibodies) genes, respectively, in affected siblings of five Saudi unrelated families.
Data indicate a decrease in transglutaminases TG1 and TG3 transcripts by about 70% in foreskins from patients with balanitis xerotica obliterans (BXO) BXO in comparison with patients without BXO and an increase in transglutaminase TG2 (show TGM2 Antibodies) mRNA levels by 2.9 fold.
In summary, we have identified three novel sequence variants, one in TGM1 and two in ALOXE3 (show ALOXE3 Antibodies), in three consanguineous families segregating lamellar ichthyosis (show LBR Antibodies) and congenital ichthyosiform erythroderma types of autosomal recessive congenital ichthyosis (show LBR Antibodies).
Our results thus indicated that the TGM1 mutation affects the formation of corni fi ed cell envelope by multiple mechanisms and leads to an almost identical clinical phenotype of generalized erythema and scales.
Two siblings with autosomal recessive congenital ichthyosis (show LBR Antibodies), were found to carry a novel aetiological TGM1 mutation that leads to the synthesis of multiple abnormal transcripts.

Mouse (Murine) Transglutaminase 1, Keratinocyte (TGM1) interaction partners

results suggest ADAM17/EGFR-driven PLCgamma1 and PKC pathways as important promoters of TG1 expression during terminal keratinocyte differentiation.
We also reveal that TGM1 modulates lung epithelial junction protein expression, suggesting a potentially protective role for hypoxia-induced TGM1 in pulmonary disease.
Characterization of TGM2 (show TGM2 Antibodies) and TGM1-TGM2 (show TGM2 Antibodies) double knock-out mouse epidermis showed that unlike TGM2 (show TGM2 Antibodies), TGM1 is indispensable for skin formation.
that the up-regulation of molecular signatures for antimicrobial and innate defense responses is characteristic of skin with a transglutaminase 1 deficiency.
This study investigated the in situ activities of transglutaminase-1 (skin-type) and transglutaminase-2 (show TGM2 Antibodies) (tissue-type) using whole mouse sections of various embryonic developmental stages and neonates.
The R142C mutation of transglutaminase 1 reduces the enzyme stability which is indispensable for development of the stratum corneum and skin barrier function and for postnatal survival of mice.
Molecular deletion of transglutaminase 2 (show TGM2 Antibodies) alone is insufficient to protect Mus (show TRPV6 Antibodies) musculus neurons from oxidative death, but inhibition of transglutaminase 1 and 2 is neuroprotective.
These studies demonstrate that tranglutaminase 2 independent activity exists in the vasculature and that Tgm1 and tgm4 (show TGM4 Antibodies) are expressed in vascular tissues
Mouse models are used to study the role of tissue transglutaminase (tTG (show TGM2 Antibodies))in Huntington's disease; its critical that the level of expression in mouse forebrain be determined. tTG (show TGM2 Antibodies) contributes to the majority of transglutaminase activity in mouse forebrain.
Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase

TGM1 Antigen Profile

Protein Summary

The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).

Gene names and symbols associated with TGM1

transglutaminase 1 (Tgm1) antibody
transglutaminase 1 (TGM1) antibody
transglutaminase 1, K polypeptide (Tgm1) antibody

2310004J08Rik antibody
ARCI1 antibody
ICR2 antibody
KTG antibody
LI antibody
LI1 antibody
TGASE antibody
Tgase1 antibody
TGK antibody
TGM1 antibody

Protein level used designations for TGM1

, , , , , , , , , , , , , , , , , , , TG(K) TGK TGase K TGase-1 epidermal TGase protein-glutamine gamma-glutamyltransferase K transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) transglutaminase 1, K polypeptide transglutaminase K transglutaminase-1 tranglutaminase 1 Protein-glutamine gamma-glutamyltransferase K K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase transglutaminase 1 isoform transglutaminase, keratinocyte K polypeptide TG K TGase 1 protein-glutamine-gamma-glutamyltransferase transglutaminase type 1

GENE ID	SPECIES
60335	Rattus norvegicus
407997	Bos taurus
403630	Canis lupus familiaris
100009118	Oryctolagus cuniculus
452814	Pan troglodytes
7051	Homo sapiens
21816	Mus musculus
100724400	Cavia porcellus

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