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TGM1 Products

(Transglutaminase 1, Keratinocyte (TGM1))

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The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). [provided by RefSeq, Jul 2008].

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Featured TGM1 Categories

TGM1 Antibodies

High quality antibodies with extensive validation data.

TGM1 ELISA Kits

Reliable ELISA kits for a wide range of species.

TGM1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TGM1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7011731
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN950045
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN520884
Quantity 50 μg
Datasheet Datasheet

Recommended TGM1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970815
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960113
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960114
Quantity 96 tests
Datasheet Datasheet

Recommended TGM1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1322632
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322634
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3095897
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TGM1 products

Tripathy, Migazzi, Costa, Roncador, Gatto, Fusco, Boeri, Albani, Juárez-Hernández, Musio, Colombo, Salmona, Wilhelmus, Drukarch, Pennuto, Basso: "Increased transcription of transglutaminase 1 mediates neuronal death in in vitro models of neuronal stress and Aβ1-42-mediated toxicity." in: Neurobiology of disease, Vol. 140, pp. 104849, (2020) (PubMed).

Terazawa, Mori, Nakajima, Yasuda, Imokawa et al.: "The UVB-Stimulated Expression of Transglutaminase 1 Is Mediated Predominantly via the NFκB Signaling Pathway: New Evidence of Its Significant Attenuation through the Specific Interruption of the ..." in: PLoS ONE, Vol. 10, Issue 8, pp. e0136311, (2015) (PubMed).

Kirschner, Rosenthal, Furuse, Moll, Fromm, Brandner: "Contribution of tight junction proteins to ion, macromolecule, and water barrier in keratinocytes." in: The Journal of investigative dermatology, Vol. 133, Issue 5, pp. 1161-9, (2013) (PubMed).

Yuki, Komiya, Kusaka, Kuze, Sugiyama, Inoue: "Impaired tight junctions obstruct stratum corneum formation by altering polar lipid and profilaggrin processing." in: Journal of dermatological science, Vol. 69, Issue 2, pp. 148-58, (2013) (PubMed).

Yang, Chevolot, Géhin, Solassol, Mange, Souteyrand, Laurenceau: "Improvement of protein immobilization for the elaboration of tumor-associated antigen microarrays: application to the sensitive and specific detection of tumor markers from breast cancer sera." in: Biosensors & bioelectronics, Vol. 40, Issue 1, pp. 385-92, (2012) (PubMed).

Miller, Westmoreland, Evangelous, Graham, Sledge, Nesathurai: "Acute traumatic spinal cord injury induces glial activation in the cynomolgus macaque (Macaca fascicularis)." in: Journal of medical primatology, Vol. 41, Issue 3, pp. 202-9, (2012) (PubMed).

Farasat, Wei, Herman, Liewehr, Steinberg, Bale, Fleckman, Toro: "Novel transglutaminase-1 mutations and genotype-phenotype investigations of 104 patients with autosomal recessive congenital ichthyosis in the USA." in: Journal of medical genetics, Vol. 46, Issue 2, pp. 103-11, (2009) (PubMed).

Zhang, Xing, Ma, Gong, Chin, Zhuang: "Transglutaminase-1 regulates renal epithelial cell proliferation through activation of Stat-3." in: The Journal of biological chemistry, Vol. 284, Issue 5, pp. 3345-53, (2009) (PubMed).

Ponnusamy, Pang, Annamaraju, Zhang, Gong, Chin, Zhuang: "Transglutaminase-1 protects renal epithelial cells from hydrogen peroxide-induced apoptosis through activation of STAT3 and AKT signaling pathways." in: American journal of physiology. Renal physiology, Vol. 297, Issue 5, pp. F1361-70, (2009) (PubMed).

Synonyms and alternative names related to TGM1

transglutaminase 1 (Tgm1), transglutaminase 1 (TGM1), transglutaminase 1, K polypeptide (Tgm1), 2310004J08Rik, ARCI1, ICR2, KTG, LI, LI1, TGASE, Tgase1, TGK, TGM1

Protein level used designations for TGM1

  • TG(K)
  • TGK
  • TGase K
  • TGase-1
  • epidermal TGase
  • protein-glutamine gamma-glutamyltransferase K
  • transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
  • transglutaminase 1, K polypeptide
  • transglutaminase K
  • transglutaminase-1
  • tranglutaminase 1
  • Protein-glutamine gamma-glutamyltransferase K
  • K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase
  • transglutaminase 1 isoform
  • transglutaminase, keratinocyte
  • K polypeptide
  • TG K
  • TGase 1
  • protein-glutamine-gamma-glutamyltransferase
  • transglutaminase type 1
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