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may act as an androgen-regulated transglutaminase [RGD, Feb 2006].. Additionally we are shipping TGM4 Antibodies (109) and TGM4 Kits (9) and many more products for this protein.
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Human TGM4 Protein expressed in Wheat germ - ABIN1322640
Jiang, Ye, Sanders, Ruge, Kynaston, Ablin, Mason: Prostate transglutaminase (TGase-4, TGaseP) enhances the adhesion of prostate cancer cells to extracellular matrix, the potential role of TGase-core domain. in Journal of translational medicine 2014
TGM4 is a prostatic secretory molecule with critical role in male reproduction.
indicated that transglutaminase 4 may serve as a potential predictor of biochemical recurrence of prostate cancer
Evidence that the retinoic acid receptor gamma plays a major role in the regulation of the hTGP gene and that presence of the androgen receptor, but not its transcriptional transactivation activity, is critical for hTGP transcription.
CDKN2A, GATA3, CREBBP, ITGA2, NBL1 and TGM4 were down-regulated in the prostate carcinoma glands compared to the corresponding normal glands
The presence of TGase-4 has a biological impact on a prostate cancer cell's response to MDA-7.
TGase-4 expression is intrinsically linked to the activation of RON in prostate cancer cells and that this autoactivation of RON contributes to the increased cell motility in TGase-4 expressing cells.
The expression status of human transglutaminase 4 in benign prostate hyperplasia (BPH) and prostate cancer was analyzed.
transglutaminase 4 has a relatively wide profile of expression in human cancer cell lines
TGase-4 plays a pivotal role in the interaction between endothelial cells and prostate cancer cells, an action which is independent of the ROCK pathway.
male mice knockouts for transglutaminase IV (Tgm4) fail to form a copulatory plug, demonstrating that this gene is necessary for plug formation and lending a powerful new genetic tool to begin characterizing plug function
These studies demonstrate that tranglutaminase 2 independent activity exists in the vasculature and that Tgm1 and tgm4 are expressed in vascular tissues
The androgen-dependent SVS I is exclusively expressed in the luminal epithelium of seminal vesicle; Gln232 and Gln254 are the major TG4-reactive residues on SVS I and and TG4 is much stronger than TG2 to cross-link the glutamine residues in SVS I.
may act as an androgen-regulated transglutaminase
transglutaminase 4 (prostate)
, TGase P
, prostate transglutaminase
, prostate-specific transglutaminase
, protein-glutamine gamma-glutamyltransferase 4
, transglutaminase P
, experimental autoimmune prostatitis antigen 1
, dorsal prostate transglutaminase
, dorsal protein 1