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TRAM1 encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. Additionally we are shipping TRAM1 Antibodies (55) and TRAM1 Kits (5) and many more products for this protein.
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TRAM1 (show NCOA3 Proteins) protect HepG2 cells from palmitate-induced insulin (show INS Proteins) resistance. The protection of TRAM1 (show NCOA3 Proteins) to HepG2 cells is through endoplasmic reticulum stress-JNK (show MAPK8 Proteins) pathway.
TRAM1 (show NCOA3 Proteins) plays an essential role in the M1 polarization of microglia. TRAM1 (show NCOA3 Proteins) increases M1-related gene expression.
These data indicate that TRAM is recognized by the signal recognition particle and translocon components, and suggest a membrane topology with eight transmembrane segments, including several poorly hydrophobic segments.
This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause.
translocating chain-associated membrane protein 1
, translocating chain-associating membrane protein
, translocation-associating membrane protein 1
, translocating chain-associating membrane protein 1
, translocation associated membrane protein 1
, Translocation-associated membrane protein 1
, translocating chain-associated membrane protein 1-like 1
, translocation associated membrane protein 1-like 1