Transmembrane 7 Superfamily Member 2 Proteins (TM7SF2)

Involved in the conversion of lanosterol to cholesterol..

list all proteins Gene Name GeneID UniProt
Mouse TM7SF2 TM7SF2 73166 Q71KT5
Human TM7SF2 TM7SF2 7108 O76062
Rat TM7SF2 TM7SF2 293688  
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Top Transmembrane 7 Superfamily Member 2 Proteins at antibodies-online.com

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,649.05
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,616.87
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Escherichia coli (E. coli) Cow His tag   100 μg Log in to see 11 Days
$718.30
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More Proteins for Transmembrane 7 Superfamily Member 2 (TM7SF2) Interaction Partners

Mouse (Murine) Transmembrane 7 Superfamily Member 2 (TM7SF2) interaction partners

  1. Tm7sf2 deficiency during liver regeneration alters lipid metabolism and generates a stress condition, which, in turn, transiently unbalances hepatocytes cell cycle progression.

  2. The Tm7sf2 insufficiency is responsible for the inhibition of the NF-kappaB (show NFKB1 Proteins) signaling.

  3. the loss of Tm7sf2 alters the expression of proteins involved in epidermal differentiation by reducing the levels of cholesterol sulfate

  4. These results show a significant increase in renal TNFalpha (show TNF Proteins) expression after tunicamycin exposure and in the oedematogenic response in Tm7sf2(-/-) mice.

  5. several genes involved in cell-cycle progression are downregulated in the liver of Tm7sf2((-/-)) mice, whereas genes involved in xenobiotic metabolism are upregulated.

Human Transmembrane 7 Superfamily Member 2 (TM7SF2) interaction partners

  1. Data suggest that, besides the SRE motif, both the inverted CCAAT-box and GC-box2 are essential for full TM7SF2 promoter activation by SREBP-2 (show SREBF2 Proteins).

  2. LBR (show LBR Proteins) mutant variants and sterol reductases can severely interfere with the regular organization of the nuclear envelope and the endoplasmic reticulum.

  3. Results show that the TM7SF2 gene product SR-1 and six chimeras containing SR-1 and Neurospora erg-3 (show SC5DL Proteins) sequences fail to complement sterol c-14 reductase mutants in Neurospora and yeast.

Transmembrane 7 Superfamily Member 2 (TM7SF2) Protein Profile

Protein Summary

Involved in the conversion of lanosterol to cholesterol.

Gene names and symbols associated with TM7SF2

  • transmembrane 7 superfamily member 2 (TM7SF2)
  • transmembrane 7 superfamily member 2 (Tm7sf2)
  • transmembrane 7 superfamily member 2 (tm7sf2)
  • transmembrane 7 superfamily member 2 L homeolog (tm7sf2.L)
  • 3110041O18Rik protein
  • ANG1 protein
  • C14SR protein
  • Dhcr14 protein
  • DHCR14A protein
  • NET47 protein
  • tm7sf2 protein
  • zgc:103611 protein

Protein level used designations for TM7SF2

transmembrane 7 superfamily member 2 , C-14 sterol reductase , delta(14)-sterol reductase , delta-14-SR , sterol C14-reductase , another new gene 1 protein , putative sterol reductase SR-1 , transmembrane 7 superfamily member 2 L homeolog

GENE ID SPECIES
100037702 Ovis aries
73166 Mus musculus
7108 Homo sapiens
282384 Bos taurus
293688 Rattus norvegicus
100725462 Cavia porcellus
494054 Danio rerio
379527 Xenopus laevis
100056588 Equus caballus
476027 Canis lupus familiaris
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