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TM9SF2 encodes a member of the transmembrane 9 superfamily. Additionally we are shipping TM9SF2 Antibodies (24) and many more products for this protein.
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A conserved immunoreceptor tyrosine-based inhibition motif exists in the cytoplasmic domain between transmembrane domains 7 & 8 in TM9SF2. A conserved TRAF2 (show TRAF2 Proteins) binding domain is predicted in the cytoplasmic regions of TM9SF2.
Among the genes enriched in this screening, the authors found that TM9SF2 is critical for N-sulfation of heparan sulfate and therefore for chikungunya virus infection because it is involved in the proper localization and stability of NDST1 (show NDST1 Proteins).
This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome.
76 kDa membrane protein
, transmembrane protein 9 superfamily member 2
, transmembrane 9 superfamily member 2
, Transmembrane 9 superfamily member 2