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Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Additionally we are shipping and many more products for this protein.
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Residues contributing to the ion-conducting pore have been defined and provide the first clues about the mechanistic link between these very different functions of golgi anti-apoptotic protein (GAAP) [review].
These results suggest that the TMBIM family has comparable functions in the maintenance of intracellular Ca(2 (show CA2 Antibodies)) homeostasis in a wide variety of tissues
The hGAAP is a novel regulator of focal adhesion dynamics, cell adhesion, and migration by controlling localized Ca(2+)-dependent activation of calpain.
GAAP (show HIVEP1 Antibodies) can oligomerize in a pH-regulated manner, and monomeric GAAP (show HIVEP1 Antibodies) is functional.
Taken together, the proposed interaction between Chlamydia pneumoniae protein CPn0809 and GAAP (show HIVEP1 Antibodies) modulates bacterial growth in A549 cells.
Data indicate that GAAP (show HIVEP1 Antibodies) and BI-1 have a six membrane-spanning topology with cytosolic N and C termini and a C-terminal reentrant loop.
Stable expression of both viral GAAP (show HIVEP1 Antibodies) (v-GAAP (show HIVEP1 Antibodies)) and human GAAP (show HIVEP1 Antibodies) (h-GAAP (show HIVEP1 Antibodies)), which is expressed in all human tissues tested, inhibited apoptosis induced by intrinsic and extrinsic apoptotic stimuli
The tmbim4 may participate in cell death regulation by interacting with proteins of Bcl-2 (show BCL2 Antibodies) family, promoting tumor metastasis, which is deduced from the evolutionary conservation of the membrane protein family containing multiple membrane spanning segments
Data demonstrate that h-GAAP (show HIVEP1 Antibodies) modulates intracellular Ca(2 (show CA2 Antibodies)+) fluxes induced by both physiological and apoptotic stimuli.
Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release (By similarity).
Golgi anti-apoptotic protein
, protein lifeguard 4
, transmembrane BAX inhibitor motif-containing protein 4