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May play a role in the process of maturation of dendritic cells. Additionally we are shipping TMEM176B Kits (4) and TMEM176B Proteins (3) and many more products for this protein.
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Study characterized Tmem176a and b expression in RORgamma t+ lymphocytes at transcriptional and protein levels and present evidence that both genes exert a redundant ion channel function related to a colocalisation in close proximity to the Golgi apparatus.
human TMEM176A and 176B protein levels are significantly elevated in lymphoma, but not in normal tissues
myogenic differentiation is achieved through the specific interaction between Cry2 and Bclaf1, which stabilizes mRNAs encoding cyclin D1, a G1/S phase transition regulator, and Tmem176b, a transmembrane regulator for myogenic cell fusion.
Tmem176b induces the differentiation of myoblasts into an osteoblast lineage.
data identify the downregulation of Clast1/LR8 as a potentially important mechanism by which oncogenic Ras-mediated neoplastic transformation occurs
These data suggest that Tmem176B and Tmem176A associate to form multimers and restrain dendritic cell maturation.
The Clast1 gene is ubiquitously expressed in various organs of adult mice and is required for development of cerebellar granule cells.
May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells (By similarity).
transmembrane protein 176B
, LR8-like protein
, tolerance-related and induced transcript protein