Trefoil Factor 2 (TFF2) ELISA Kits

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Additionally we are shipping Trefoil Factor 2 Antibodies (121) and Trefoil Factor 2 Proteins (36) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TFF2 7032 Q03403
TFF2 116592 Q09030
TFF2 21785  
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Top Trefoil Factor 2 ELISA Kits at

Showing 10 out of 36 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 24.7 pg/mL 62.5 pg/mL - 4000 pg/mL 96 Tests 13 to 16 Days
Mouse 0.066 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
Rat 0.064 ng/mL 0.156 ng/mL - 10 ng/mL Typical Standard Curve 96 Tests 15 to 17 Days
Dog 0.2 ng/mL 0.78-50 ng/mL   96 Tests 15 to 18 Days
Pig 1.56 ng/mL n/a   96 Tests 15 to 18 Days
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
Monkey 18.75 pg/mL 31.25-2000 pg/mL   96 Tests 12 to 14 Days
  96 Tests 26 to 36 Days
  96 Tests 15 to 18 Days

Top referenced Trefoil Factor 2 ELISA Kits

  1. Human Trefoil Factor 2 ELISA Kit for Sandwich ELISA - ABIN414550 : Huang, Zhang, Lu, Wu, Wang, Zhang, Ding: Serum trefoil factor 3 is a promising non-invasive biomarker for gastric cancer screening: a monocentric cohort study in China. in BMC gastroenterology 2014 (PubMed)
    Show all 2 Pubmed References

  2. Human Trefoil Factor 2 ELISA Kit for Sandwich ELISA - ABIN577520 : Xing, Jia, He, Shi, Fang, Song, Zhang, Zhao, Fu, Li: Establishment of the tree shrew as an alcohol-induced Fatty liver model for the study of alcoholic liver diseases. in PLoS ONE 2016 (PubMed)

More ELISA Kits for Trefoil Factor 2 Interaction Partners

Human Trefoil Factor 2 (TFF2) interaction partners

  1. Serum concentrations of TFF1 and TFF3 but not TFF2 are higher in women with breast cancer than in women without breast cancer.

  2. results suggest that TFF1 and TFF3, but not TFF2, may have a role in breast tumor pathogenesis

  3. TFF2 is a promising immunohistochemical marker and its identification in uterine cervical secretion is a potentially useful diagnostic test for endocervical glandular lesions with gastric differentiation.

  4. The urine TFF1 and TFF3 levels significantly increased with the progression of chronic kidney disease stages, but not the urine TFF2 levels.

  5. Data show that trefoil factor 2 (TFF2( urine levels continuously decreased with disease progression, TFF2 serum concentrations progressively increased from the early to later chronic kidney disease (CKD) stages, indicating changes in renal function and offering the potential to examine the course of CKD.

  6. this work reveals that TFF2 has tumor-suppressor activity, which may, in part, be regulated by SMAD4.

  7. Data indicate that the antitumor activity of trefoil factor 2 (TFF2) is mediated by an interaction with the transcription factor Sp3 (Sp3) in gastric cancer cells.

  8. Data show the important functions of TFF2 in the gastric mucus barrier, mucus epithelia, immune system, central nervous system, and during fertilization. It has been shown to interact with the gastric mucin MUC6. [Review]

  9. These findings suggest that the rs184432 and rs225359 polymorphisms in TFF1 have protective effects for GC and contribute to the development of GC in Korean individuals.

  10. We reproducibly associate higher expression of the ligand-receptor axis of TFF2 and CXCR4 with BRAF V600E-mutant colon cancer

  11. protease-activated receptor 4 and Trefoil factor 2 are expressed in human colorectal cancer

  12. The structural features of the N-linked N,N'-di-N-acetyllactosediamine-inducing determinant on human TFF2 are discussed.

  13. Human TTF2 is a lectin that binds alpha-GlcNAc-capped mucin 6 g with antibiotic activity against Helicobacter pylori.

  14. Significantly higher levels of TFF2 were in patients with Multiple Organ Dysfunction Syndrome.

  15. There is an association between TFF2 and TFF3 polymorphisms and risk of atrophic gastritis and gastric cancer in Chinese people.

  16. Human gastric TFF2 peptide contains an N-linked fucosylated N,N'-diacetyllactosediamine (LacdiNAc) oligosaccharide

  17. this study indicated that Sp3 was a major regulator of TFF2 expression.

  18. Report TFF2 expression in normal/diseased pancreas and suggest role in tumor cell migration.

  19. Report a novel TFF2 splice variant (EX2TFF2) which correlates with longer overall survival time in cholangiocarcinoma.

  20. TFF2 messenger RNA expression is significantly increased in nasal mucosal brushings during asthma exacerbations in children.

Pig (Porcine) Trefoil Factor 2 (TFF2) interaction partners

  1. Low intestinal TFF2 expression was measured at early maturation stages. Weaning, however, was associated with a distinct response of increased TFF2 expression, indicating an important role in enhancing mucosal integrity.

Mouse (Murine) Trefoil Factor 2 (TFF2) interaction partners

  1. this work demonstrates that lung macrophages rely upon Trefoil factor 2 to promote epithelial proliferation following damage caused by sterile wounding, Nippostrongylus brasiliensis or Bleomycin sulfate

  2. we show a previously unappreciated role for TFF2, produced by either hematopoietic or nonhematopoietic sources, as a pro-proliferative factor for lung epithelial cells under steady-state and infectious injury conditions.

  3. the Tg(Tff1-CreERT2;Tff2-rtTA;Tff3-Luc) strain can confer intermittent transgene expression to gastric epithelial cells that have undergone previous gene modification, and may be suitable to genetically model therapeutic intervention during development, tumorigenesis, and other genetically tractable diseases

  4. Splenic TFF2 is released by vagally modulated memory T cells to suppress expansion of myeloid-derived suppressor cells (MDSC) through CXCR4. TFF2 is important to the anti-inflammatory reflex arc and has an essential role in arresting MDSC proliferation.

  5. hnRNP A1 improves intestinal injury in anti-CD3 antibody-induced enteritis mice through the upregulation of TFF2, which regulates apoptosis and enhances epithelial restoration

  6. Overexpressing Tff2 in cultured cells reduced doubling time in vitro and rapidly increased xenograft tumor size in vivo

  7. Epithelial TFF2 is an important endogenous regulator of gut mucosal homeostasis that can modulate immune and epithelial compartments.

  8. The Tff2 gene is expressed in the hypothalamus and is regulated by food intake. Knockout mice are leaner and have reduced fat mass compared to wild-type.

  9. The increased expression of endogenous TFF2 in response to chronic allergic inflammation is insufficient to prevent the progression of airway inflammation and remodeling in a model of chronic allergic airways disease.

  10. TFF2 functions as a regulator of intestinal homeostasis that suppresses Toxoplasma gondii-driven type 1 inflammation.

  11. TFF2 (trefoil factor 2), an epithelial cell-derived repair molecule, is needed for the control of lung injury caused by the hookworm parasite Nippostrongylus brasiliensis and for type 2 immunity after infection.

  12. results suggest that during retinal cell death periods, requiring a tightly regulated balance between cell survival and cell death, TFF2 acts pro-proliferative and pro-apoptotic at least in developing mouse retinae cultured in vivo

  13. functional NHE2, but not NHE1, is essential for mouse gastric epithelial restitution and TFFs activate epithelial repair via NHE2

  14. Trefoil factor 2 plays a role in the pathogeneasis of airway remodeling in airway disease in the mouse model.

  15. TFF2 transcript-expressing cells are progenitors for mucus neck, parietal and zymogenic, but not for pit or enterochromaffin-like cell lineages in the oxyntic gastric mucosa

  16. TFF2 negatively regulates preneoplastic progression and subsequent tumor development in the stomach, a role that is subverted by promoter methylation during H pylori infection

  17. TFF2 plays a role in restitution after acute gastric epithelial injury, and the effect of exogenous trefoil peptides promote acute wound repair which does not require cyclooxygenase activity.

  18. TFF2 is an allergen-induced lung gene product differentially regulated by Th2 cytokines and STAT6

  19. Intestinal trefoil factor is involved in protection against and recovery from intestinal mucositis induced by radiation and chemotherapy.

  20. spasmolytic peptide expressing metaplasia represents a precursor lineage for the development of dysplasia in this animal model of gastric carcinogenesis.

Trefoil Factor 2 (TFF2) Antigen Profile

Antigen Summary

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Gene names and symbols associated with Trefoil Factor 2 (TFF2) ELISA Kits

  • trefoil factor 2 (TFF2) antibody
  • trefoil factor 2 (Tff2) antibody
  • trefoil factor 2 S homeolog (tff2.S) antibody
  • trefoil factor 2 (spasmolytic protein 1) (Tff2) antibody
  • mSP antibody
  • p4 antibody
  • p4-a antibody
  • PSP antibody
  • sml1 antibody
  • SP antibody
  • TFF2 antibody
  • xP4 antibody
  • xp4.1 antibody

Protein level used designations for Trefoil Factor 2 (TFF2) ELISA Kits

trefoil factor 2 , trefoil factor 2 (spasmolytic protein 1) , trefoil factor family peptide 2 , spasmolysin , spasmolytic polypeptide , spasmolytic protein 1 , pancreatic spasmolytic polypeptide , SP , spasmolytic peptide , spasmolytic peptide 1 , spasmolytic polypeptide 1 , P-domain peptide , TFF p4.1 , putative gastrointestinal growth factor xP4

418534 Gallus gallus
470096 Pan troglodytes
100170653 Felis catus
7032 Homo sapiens
397420 Sus scrofa
116592 Rattus norvegicus
403489 Canis lupus familiaris
616105 Bos taurus
101787738 Cavia porcellus
378510 Xenopus laevis
21785 Mus musculus
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