anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) Antibodies

TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).[supplied by OMIM, Mar 2008].. Additionally we are shipping TREML2 Kits (14) and TREML2 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TREML2 79865 Q5T2D2
TREML2 328833 Q2LA85
TREML2 680844  
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Top anti-TREML2 Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-TREML2 Antibody Titration: 0.2-1 ug/ml Positive Control: 721_B cell lysate TREML2 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TREML2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Hela cell lysate WB Suggested Anti-TREML2 Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA   100 μL Log in to see 14 to 16 Days
$183.12
Details
Mouse Rat Un-conjugated CyTOF, FACS Detection of TREML2 in M1 Mouse Cell Line by Flow Cytometry. M1 mouse myeloid leukemia cell line was stained with Rat Anti-Mouse TREML2/TLT-2 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$238.43
Details
Mouse Sheep Un-conjugated CyTOF, FACS, WB Detection of TREML2/TLT-2 in M1 Mouse Cell Line by Flow Cytometry. M1 mouse myeloid leukemia cell line was stained with Mouse TREML2/TLT-2 Antigen Affinity-purified Polyclonal Antibody. Detection of Mouse TREML2/TLT-2 by Western Blot. Western blot shows lysates of mouse spleen tissue. PVDF Membrane was probed with 1 ug/mL of Mouse TREML2/TLT-2 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Log in to see 8 to 9 Days
$300.58
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB TREML2 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
$473.93
Details
Human Rabbit Un-conjugated ELISA   100 μL Log in to see 14 to 16 Days
$312.53
Details
Mouse Rat Un-conjugated FACS   100 μg Log in to see 11 to 14 Days
$969.83
Details
Mouse Rat PE FACS 50 μg Log in to see 10 to 12 Days
$140.39
Details

More Antibodies against TREML2 Interaction Partners

Human Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) interaction partners

  1. Mutation of TREML2 is a major factor leading to ankylosing spondylitis for HLA-B27 (+) members in a large family and that TREML2 is also a susceptibility gene promoting the development of ankylosing spondylitis in HLA-B27 (+) individuals.

  2. A missense variant in TREML2 was associated with a reduced risk of Alzheimer's Disease in a Han Chinese population.

  3. Study characterized the expression of TREM genes in cerebellum and temporal cortex and determined TREML1 and TREM2 to be the only reliably expressed TREM genes in these brain regions; identified rs9357347 as a putative regulatory variant that is associated with protection from Alzheimer's disease and with increased TREML1 and TREM2 brain levels.

  4. Its mutation plays a role in pathogenesis of Alzheimer's disease.

  5. Missense variant in TREML2 protects against Alzheimer's disease.

  6. TLT2 may be involved in the innate immune response based on its expression profile and the fact that it is up-regulated in response to inflammation.

  7. analysis of an interaction between B7-H3 and TLT-2 that preferentially enhances CD8(+) T cell activation

  8. Data do not point to a role for TREML2 as a receptor for B7-H3.

Mouse (Murine) Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) interaction partners

  1. TREM2 and TREML2 play opposite roles in microglia activation

  2. Thus, our studies identified TLT2 as an engulfment receptor for apoptotic cells.

  3. TLT2 ligation enhances the neutrophil response to the formylated peptide FMLF, leading to increased reactive oxygen species production, degranulation, and chemotaxis

  4. (+) T-cell effector function, possibly by ligation of TLT-2 on tumour-infiltrating CD8(+) T cells at the local tumour site.

  5. TLT2 may be involved in the innate immune response based on its expression profile and the fact that it is up-regulated in response to inflammation.

  6. analysis of an interaction between B7-H3 and TLT-2 that preferentially enhances CD8(+) T cell activation

  7. Data do not point to a role for TREML2 as a receptor for B7-H3.

TREML2 Antigen Profile

Protein Summary

TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003

Gene names and symbols associated with TREML2

  • triggering receptor expressed on myeloid cells like 2 (TREML2) antibody
  • triggering receptor expressed on myeloid cells-like 2 (TREML2) antibody
  • triggering receptor expressed on myeloid cells-like 2 (Treml2) antibody
  • AW049306 antibody
  • C6orf76 antibody
  • dJ238O23.1 antibody
  • Gm750 antibody
  • TLT-2 antibody
  • Tlt2 antibody
  • TREM-B2V1 antibody

Protein level used designations for TREML2

triggering receptor expressed on myeloid cells-like 2 , triggering receptor expressed on myeloid cells , trem-like transcript 2 protein , triggering receptor expressed on myeloid cells-like protein 2 , TLT-2 , triggering receptor expressed on myeloid cells-like 2a dominant

GENE ID SPECIES
748479 Pan troglodytes
769228 Gallus gallus
79865 Homo sapiens
481791 Canis lupus familiaris
515548 Bos taurus
328833 Mus musculus
680844 Rattus norvegicus
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