Tryptophan Rich Basic Protein Proteins (WRB)

WRB encodes a basic nuclear protein of unknown function. Additionally we are shipping WRB Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
WRB 7485 O00258
Mouse WRB WRB 71446 Q8K0D7
Rat WRB WRB 288233 Q6P6S5
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Top WRB Proteins at

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

WRB Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Tryptophan Rich Basic Protein (WRB) Interaction Partners

Zebrafish Tryptophan Rich Basic Protein (WRB) interaction partners

  1. Wrb may have tissue-specific functions in the visual system and heart, or can maintain dual functions even in the same tissue. The selectivity of the defects at sensory neuron ribbon synapses suggests unique biosynthetic demands for cells bearing ribbon synapses, but may also point to a novel role for Wrb acting through the GET pathway in synaptic function.

  2. WRB plays a critical role in synaptic functions in inner-ear hair cells and retinal photoreceptors.

Human Tryptophan Rich Basic Protein (WRB) interaction partners

  1. WRB gene contains a maternally imprinted differentially methylated region (DMR (show WDR20 Proteins)). The maternally inherited 5mCpG imprints at the WRB DMR (show WDR20 Proteins) are uncoupled from the parental allele expression of WRB and ten neighboring genes in twelve biosamples (brain, blood, fallopian tube, fetal large and small intestine, hESCs, large airway epithelial cells, thyroid, muscle, epidermal keratinocytes, ovary, skin, and testis).

  2. Results indicate calcium-modulating cyclophilin ligand (CAML (show CAMLG Proteins)) and WRB as components of the TRC40 (show ASNA1 Proteins) receptor complex and a crucial mechanism for driving ER membrane insertion of TA proteins in mammalian cells.

  3. The coiled-coil domain of WRB is the binding site for TRC40/Asna1 (show ASNA1 Proteins).

WRB Protein Profile

Protein Summary

This gene encodes a basic nuclear protein of unknown function. The gene is widely expressed in adult and fetal tissues. Since the region proposed to contain the gene(s) for congenital heart disease (CHD) in Down syndrome (DS) patients has been restricted to 21q22.2-22.3, this gene, which maps to 21q22.3, has a potential role in the pathogenesis of Down syndrome congenital heart disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with WRB

  • tryptophan rich basic protein (WRB)
  • tryptophan rich basic protein (wrb)
  • tryptophan rich basic protein L homeolog (wrb.L)
  • tryptophan rich basic protein (Wrb)
  • 5530402J05Rik protein
  • C030018G21Rik protein
  • Chd5 protein
  • DKFZp469L094 protein
  • mCHD5 protein
  • MGC89989 protein
  • MGC115192 protein
  • pwi protein
  • UCP-1 protein
  • wrb protein
  • wu:ft06h05 protein
  • zgc:101856 protein

Protein level used designations for WRB

tryptophan-rich protein , pinball wizard , tail-anchored protein insertion receptor WRB , tryptophan-rich basic protein , tryptophan rich basic protein , Tryptophan-rich protein , congenital heart disease 5 , congenital heart disease 5 protein

100328654 Oryctolagus cuniculus
335756 Danio rerio
448737 Xenopus (Silurana) tropicalis
474115 Pan troglodytes
608126 Canis lupus familiaris
703947 Macaca mulatta
770415 Gallus gallus
100137464 Papio anubis
100173514 Pongo abelii
100271915 Oryzias latipes
734467 Xenopus laevis
100220620 Taeniopygia guttata
7485 Homo sapiens
71446 Mus musculus
288233 Rattus norvegicus
509739 Bos taurus
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