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anti-Tubulin tyrosine Ligase-Like Family, Member 5 (TTLL5) Antibodies

TTLL5 encodes a member of the tubulin tyrosine ligase like protein family. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TTLL5 23093 Q6EMB2
Anti-Mouse TTLL5 TTLL5 320244 Q8CHB8
TTLL5    
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Top anti-Tubulin tyrosine Ligase-Like Family, Member 5 Antibodies at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p)   100 μL Log in to see 11 to 12 Days
$460.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: TTLL5 Antibody - Staining of human fallopian tube shows moderate cytoplasmic positivity in glandular cells and cilia. Immunocytochemistry/Immunofluorescence: TTLL5 Antibody - Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Horse Rabbit Un-conjugated IP, WB   100 μL Log in to see 7 to 9 Days
$595.83
Details
Human Rabbit Un-conjugated IP   100 μL Log in to see 7 to 9 Days
$595.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated IP   100 μL Log in to see 7 to 9 Days
$556.31
Details

TTLL5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,


Horse (Equine)


Top referenced anti-Tubulin tyrosine Ligase-Like Family, Member 5 Antibodies

  1. Human Polyclonal TTLL5 Primary Antibody for IHC (p) - ABIN5590346 : Sergouniotis, Chakarova, Murphy, Becker, Lenassi, Arno, Lek, MacArthur, Bhattacharya, Moore, Holder, Robson, Wolfrum, Webster, Plagnol: Biallelic variants in TTLL5, encoding a tubulin glutamylase, cause retinal dystrophy. in American journal of human genetics 2014 (PubMed)

More Antibodies against Tubulin tyrosine Ligase-Like Family, Member 5 Interaction Partners

Human Tubulin tyrosine Ligase-Like Family, Member 5 (TTLL5) interaction partners

  1. in a study of 3 family members from 2 generations, identified in a previously misdiagnosed incomplete congenital stationary night blindness (icCSNB) case a splice-site mutation in intron 3 of TTLL5 (c.182-3_182-1delinsAA); reinvestigation of the clinical data corrected the diagnosis to cone dystrophy

  2. 5 homozygous variants [p.(Asp594fs), p.(Gln117*), p.(Met712fs), p.(Ile756Phe) and p.(Glu543Lys)] in TTLL5, in 8 patients from 6 families were identified. 2 male patients carrying truncating TTLL5 variants also displayed a reduction in sperm motility and infertility, whereas those carrying missense changes were fertile. TTLL has multiple viable isoforms, being highly expressed in retina, testis and spermatozoon flagellum.

  3. this study has performed exome sequencing in 28 individuals with a similar disease phenotype and subsequently used a casecontrol approach to identify mutations in TTLL5 as a cause of recessive retinal dystrophy (show MERTK Antibodies).

  4. This study indicates that a physiological function of STAMP in several settings is to modify cell growth rates in a manner that can be independent of steroid hormones.

  5. STAMP is an important new, downstream component of GR action in both gene activation and gene repression.

Mouse (Murine) Tubulin tyrosine Ligase-Like Family, Member 5 (TTLL5) interaction partners

  1. Mouse models carrying truncating mutations in TTLL5 gene display reduced fertility in male animals.

  2. study uncovers the pathogenic mechanism whereby absence of RPGR(ORF15 (show RPGR Antibodies)) glutamylation leads to retinal pathology in patients with TTLL5 gene mutations and connects these two genes into a common disease pathway.

  3. STAMP appears to participate in a unique, tissue-selective TTLL-mediated pathway for alpha-tubulin (show TUBA4A Antibodies) polyglutamylation that is required for sperm maturation and motility and may be relevant for male fertility.

Tubulin tyrosine Ligase-Like Family, Member 5 (TTLL5) Antigen Profile

Protein Summary

This gene encodes a member of the tubulin tyrosine ligase like protein family. This protein interacts with two glucocorticoid receptor coactivators, transcriptional intermediary factor 2 and steroid receptor coactivator 1. This protein may function as a coregulator of glucocorticoid receptor mediated gene induction and repression. This protein may also function as an alpha tubulin polyglutamylase.

Gene names and symbols associated with TTLL5

  • tubulin tyrosine ligase like 5 (TTLL5) antibody
  • tubulin tyrosine ligase-like family, member 5 (Ttll5) antibody
  • 1700048H13Rik antibody
  • 2310009M18Rik antibody
  • 4930556H18Rik antibody
  • AI428864 antibody
  • D630041K24Rik antibody
  • KIAA0998 antibody
  • mKIAA0998 antibody
  • R75373 antibody
  • Stamp antibody
  • TTLL5 antibody

Protein level used designations for TTLL5

tubulin polyglutamylase TTLL5 , tubulin tyrosine ligase-like family, member 5 , tubulin--tyrosine ligase-like protein 5 , SRC1 and TIF2 associated binding protein , SRC1 and TIF2-associated modulatory protein , polyglutamylase , tubulin tyrosine ligase like family 5

GENE ID SPECIES
100172924 Pongo abelii
23093 Homo sapiens
320244 Mus musculus
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