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Polyglutamylase which preferentially modifies alpha- tubulin. Additionally we are shipping TTLL6 Proteins (3) and many more products for this protein.
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Tubulin tyrosine ligase-like genes ttll3 and ttll6 maintain zebrafish cilia structure and motility.
Transgenic mice overexpressing Tau show TTLL6 translocalization into dendrites and decreased MT stability
The polyglutamylase TTLL6 plays a key role in the regulation of ciliary beating.
Ttll6 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.
Polyglutamylase which preferentially modifies alpha- tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step.
tubulin polyglutamylase ttll6
, tubulin polyglutamylase TTLL6
, tubulin--tyrosine ligase-like protein 6