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TDRD7 encodes a component of cytoplasmic RNA granules which are involved in determining the fate of mRNAs.
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Human Polyclonal TDRD7 Primary Antibody for IHC, IHC (p) - ABIN4358319
Ito, Mimae, Yamamoto, Hagiyama, Nakanishi, Ito, Hosokawa, Okada, Murakami, Kondo: Novel application for pseudopodia proteomics using excimer laser ablation and two-dimensional difference gel electrophoresis. in Laboratory investigation; a journal of technical methods and pathology 2012
Human cataracts and the TDRD7 gene loss-of-function mutations are strongly causally related, as the expression level of plasma TDRD7 mRNA in patients with cataracts was statistically significantly lower than in the normal control group.
present study suggests that the rs10981985 G --> A variant within the TDRD7 gene may protect against cortical age-related cataract in a Han Chinese population
study describes 2 cases of pediatric cataract with loss-of-function mutations in TDRD7; TDRD7 coimmunoprecipitates with specific lens mRNAs; required for posttranscriptional control of mRNAs critical to normal lens development and RNA granule function
results identify TRPC3 (show TRPC3 Antibodies) as a pivotal signaling gateway in Ca(2 (show CA2 Antibodies)+)-dependent control of cardiac gene expression
Tdrd7 nullizygosity causes cataract and glaucoma and arrest in spermatogenesis;TDRD7 coimmunoprecipitates with specific lens mRNAs; required for posttranscriptional control of mRNAs critical to normal lens development and RNA granule function
This gene encodes a component of cytoplasmic RNA granules which are involved in determining the fate of mRNAs. Mutation in this gene has been associated with pediatric cataracts. Mutation of the similar gene in mice has been associated with cataracts, glaucoma and a block in spermatogenesis.
, tudor domain-containing protein 7
, tudor repeat associator with PCTAIRE 2
, tudor repeat associator with PCTAIRE-2
, tudor domain-containing protein 7A