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TFIP11 is a nuclear speckle-localized protein that may play a role in spliceosome disassembly in Cajal bodies (Stanek et al., 2008 [PubMed 18367544]).[supplied by OMIM, Apr 2009]..
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the high expression and activation effect on the ERK1/2 signaling of STIP (show ELP2 Antibodies) in lymphoblastic leukemia suggest that STIP (show ELP2 Antibodies) would be a potential therapy target or diagnosis marker for leukemia.
We now report the identification of a novel molecular function of STIP (show ELP2 Antibodies) that links USP7 (show USP7 Antibodies) to the p53 (show TP53 Antibodies)-Mdm2 (show MDM2 Antibodies) pathway
Results suggest that Sip1 (show GEMIN2 Antibodies)/tuftelin (show TUFT1 Antibodies)-interacting protein (STIP (show ELP2 Antibodies), also referred to as TFIP11) may be a novel potential diagnostic and therapeutic target for non-small cell lung cancer (NSCLC).
the statistically significant association of rs2337359 upstream of TUFT1 (show TUFT1 Antibodies) with dental caries experience via meta-analysis across adult samples (p < 0.002) and the suggestive association for multiple variants in TFIP11 across child samples
Associations between TFIP11 (p=0.02), ENAM (show ENAM Antibodies) (p=0.00001), and AMELX (show AMELX Antibodies) (p=0.01) could be seen with caries independent of having MIH or genomic DNA copies of Streptococcus mutans detected by real time PCR in the Brazilian sample.
TFIP11 is a novel splicing factor (show SLU7 Antibodies) and transfected TFIP11-GFP fusion protein was found to locate in a novel subnuclear TFIP body.
These data help define the mechanism of nuclear/nuclear speckle localization of the splicing factor (show SLU7 Antibodies) TFIP11, with implications for it's function.
TFIP11 is a nuclear speckle-localized protein that may play a role in spliceosome disassembly in Cajal bodies (Stanek et al., 2008
septin and tuftelin interacting protein
, tuftelin interacting protein 11
, septin and tuftelin-interacting protein 1
, tuftelin-interacting protein 11
, tuftelin-interacting protein 33
, tuftelin-interacting protein 39
, tuftelin-interacting protein, 39 kD