Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by TNFAIP6 is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. Additionally we are shipping Tumor Necrosis Factor-Inducible Protein 6 Antibodies (44) and Tumor Necrosis Factor-Inducible Protein 6 Proteins (7) and many more products for this protein.
Showing 10 out of 39 products:
Rat (Rattus) TNFAIP6 ELISA Kit for Sandwich ELISA - ABIN858553
Kato, Okumi, Tanemura, Yazawa, Kakuta, Yamanaka, Tsutahara, Doki, Mori, Takahara, Nonomura: Adipose Tissue-Derived Stem Cells Suppress Acute Cellular Rejection by TSG-6 and CD44 Interaction in Rat Kidney Transplantation. in Transplantation 2014
our results showed that the increase of oxidative stress, activation of the NLRP3 (show NLRP3 ELISA Kits) inflammasome and NF-kappaB (show NFKB1 ELISA Kits) signaling in SAP (show APCS ELISA Kits) was substantially inhibited following administration of hMSCs or TSG-6, which was dependent on the presence of CD-44 (show CD44 ELISA Kits) receptors in acinar cells.
TSG-6 protects hepatocytes from damage by enhancing autophagy influx and contributes to liver regeneration
TSG6 functions by converting macrophages from a proinflammatory to an anti-inflammatory phenotype secondary to suppression of TLR4 (show TLR4 ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits) signaling and STAT1 (show STAT1 ELISA Kits) and STAT3 (show STAT3 ELISA Kits) activation.
This study provided the first evidence of TSG-6 secreted by mesenchymal stem cells promoting corneal epithelial wound healing in diabetic mice through activating corneal epithelial stem/progenitor cells and accelerating M2 macrophage polarization
This study shows that TSG-6 is expressed in the CNS, suggesting a role for TSG-6 in astrocyte activation and tissue repair.
Data (including data from studies in knockout mice) suggest that TSG-6 is needed for release of hyaluronan rafts (leukocyte-adhesive rafts) from apical surface of tracheal mucosa into bronchoalveolar lavage fluid as heavy chain hyaluronan complexes.
the well characterized hyaluronan-binding site in the TSG-6 Link module is not used for recognition during transfer of HCs (show HLCS ELISA Kits) onto HA.
Thus, TSG6, HA, and IalphaI were crucial factors for the settlement and probably the subsequent differentiation of MSCs.
BM-MSCs injected into mice with colitis do not localize to the intestine but instead form aggregates in the peritoneum where they produce immunoregulatory molecules, including TSG6, that reduce intestinal inflammation.
This study demonstrated that following stimulation with TNF-alpha (show TNF ELISA Kits), MSCs modulate microglia activity through TSG-6.
TSG-6 from MSCs attenuated severe burn-induced excessive inflammation via inhibiting activation of P38 (show CRK ELISA Kits) and JNK (show MAPK8 ELISA Kits) signaling.
TSG-6 secreted by human mesenchymal stem cells suppresses inflammatory reactions through p38 (show CRK ELISA Kits) and ERK (show EPHB2 ELISA Kits) in the mitogen-activated protein kinase (show MAPK1 ELISA Kits) pathway
This review will focus on the potential of mesenchymal stem/stromal cells for treatment of fibrotic diseases, with emphasis on the role of TSG-6 as a mediator of anti-inflammatory effects
Single nucleotide polymorphism in TNFAIP6 gene is associated with Systemic lupus erythematosus.
TNFAIP6 expression is significantly upregulated in human masticatory mucosa during wound healing
Data show that TNF (show TNF ELISA Kits)-stimulated gene-6 (TSG-6) interacts with chemokines through their glycosaminoglycans (GAGs)-binding sites and inhibits their binding to GAGs and endothelial cell surfaces.
The current study describes a novel mechanism linking the TSG-6 transfer of the newly described HC5 (show PSMB1 ELISA Kits) to the HA-dependent control of cell phenotype. The interaction of HC5 (show PSMB1 ELISA Kits) with cell surface HA was essential for TGFbeta1 (show TGFB1 ELISA Kits)-dependent differentiation of fibroblasts to myofibroblasts, highlighting its importance as a novel potential therapeutic target.
Data postulate that the molecular cross-linking enhanced by the multiple binding modes of the Link module might be critical for remodeling the ECM (show MMRN1 ELISA Kits) during inflammation/ovulation and might contribute to other functions of TSG-6.
TSG-6 exhibited anti-inflammatory effects during the wound healing process and cicatrization and significantly diminished hypertrophic scar formation in a rabbit ear model
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
tumor necrosis factor alpha induced protein 6
, tumor necrosis factor-inducible gene 6 protein
, tumor necrosis factor-inducible protein 6
, TNF alpha-induced protein 6
, TNF-stimulated gene 6 protein
, tumor necrosis factor alpha-induced protein 6
, tumor necrosis factor induced protein 6
, tumor necrosis factor, alpha-induced protein 6
, hyaluronate-binding protein
, tumor necrosis factor alpha-inducible protein 6
, tumor necrosis factor-stimulated gene-6 protein
, hyaluronate-binding protein PS4
, secreted hyaluronate binding protein