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The protein encoded by TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. Additionally we are shipping TSG101 Proteins (13) and TSG101 Kits (6) and many more products for this protein.
Showing 10 out of 133 products:
Hamster Monoclonal TSG101 Primary Antibody for ELISA, FACS - ABIN152256
Garrus, von Schwedler, Pornillos, Morham, Zavitz, Wang, Wettstein, Stray, Côté, Rich, Myszka, Sundquist: Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. in Cell 2001
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Human Monoclonal TSG101 Primary Antibody for IF, IHC (p) - ABIN563269
Skogberg, Gudmundsdottir, van der Post, Sandström, Bruhn, Benson, Mincheva-Nilsson, Baranov, Telemo, Ekwall: Characterization of human thymic exosomes. in PLoS ONE 2013
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Human Polyclonal TSG101 Primary Antibody for ICC, IF - ABIN4363086
Gross, Chaudhary, Bartscherer, Boutros: Active Wnt proteins are secreted on exosomes. in Nature cell biology 2012
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Cow (Bovine) Polyclonal TSG101 Primary Antibody for IHC, WB - ABIN2780037
Stefan, Claiborn, Stasiek, Chai, Ohta, Longnecker, Greally, Nicholls: Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes. in BMC genomics 2005
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Mouse (Murine) Polyclonal TSG101 Primary Antibody for IF, IHC - ABIN5664008
Yu, Yan, Yang, Wu, Ling, Chen, Tang, Tan, Cao, Wu, Yan, Wang: Platelets promote tumour metastasis via interaction between TLR4 and tumour cell-released high-mobility group box1 protein. in Nature communications 2014
Cow (Bovine) Polyclonal TSG101 Primary Antibody for WB - ABIN2780762
Surjit, Oberoi, Kumar, Lal: Enhanced alpha1 microglobulin secretion from Hepatitis E virus ORF3-expressing human hepatoma cells is mediated by the tumor susceptibility gene 101. in The Journal of biological chemistry 2006
loss of ept alters nuclear cell cycle control in developing imaginal discs and the DaPKC, presenilin, and rbf1 genes as modifiers of molecular and cellular phenotypes that result from loss of ept
analysis of genetic interactions between the Drosophila tumor suppressor gene ept and the stat92E transcription factor
The authors provide evidence that the ubiquitin (Ub) E2 variant domain of Tsg101 provides chaperone function to HIV-1 Gag that is independent of its interaction with the Pro-Thr-Ala-Pro motif, supporting the hypothesis that the domain provides a function in addition to its well-established role in cellular endosomal sorting complex required for transport factor recruitment.
In this review, HIV-infected cells have TSG101 on their surface and thus can be used in antibody-based therapies. The development of a monoclonal antibody CB8-2 lessens the assembly of viruses from infected cells
Results indicate that Vpr overcomes the effects of TSG101 overexpression to support viral production by competing with TSG101 to bind Gag.
our studies reveal that Tsg101 plays a role in the trafficking of macropinocytosed Kaposi's sarcoma-associated herpesvirus in the endothelial cells
Knockdown of LAMP2A, a CMA-related protein, and TSG101, an mA-related protein, significantly but only partially decreased the punctate accumulation of GAPDH (show GAPDH Antibodies)-HT in AD293 cells and primary cultured rat cortical neurons.
the variant alleles of TSG101 rs2292179 and ATF2 (show ATF2 Antibodies) rs3845744 were associated with a reduced risk of breast cancer, particularly for subjects with BMI <24 (kg/m(2)) and postmenopausal women, respectively
TSGDelta154-1054 splice variant increases TSG101 oncogenicity by inhibiting its E3-ligase-mediated proteasomal degradation.
Results show that TSG101 bidirectionally modulates cell invasion through regulating MMP-9 (show MMP9 Antibodies) mRNA expression in different cell types.
TSG101 plays an important role in the development of hepatocellular carcinoma
Expression of tsg101 mRNA and of TSG101 protein were significantly higher in the oxaliplatin resistant cell line than parent HT-29 cels.
Tsg101 was deleted from mature oligodendroglia in vivo. This resulted in severe spongiform encephalopathy, histopathologically similar to that observed in Mgrn1 (show MGRN1 Antibodies) null mutant mice but with a more rapid onset.
BLOS1 (show BLOC1S1 Antibodies) interacts with sorting nexin 2 (show SNX2 Antibodies) and the ESCRT-I (show VPS28 Antibodies) component TSG101 to mediate the sorting of EGFR (show EGFR Antibodies) into endosomal compartments
pigment-type switching likely requires MGRN1's ubiquitin ligase activity but not its ability to bind TSG101 or NEDD4.
Tsg101 has a role in expression of EGFR (show EGFR Antibodies) and ErbB2 (show ERBB2 Antibodies) and preventing induction of autophagy prior to cell death
show that ubiquitin recognition by TSG101 is required for cSMAC formation, T cell receptor (TCR) microcluster signal termination, TCR downregulation.
Negative regulation of cell growth and differentiation by TSG101 through association with p21(Cip1/WAF1 (show CDKN1A Antibodies)).
Targeted deletion results in cell cycle arrest and p53 (show TP53 Antibodies)-independent cell death
our results suggest that Tsg101 is required for normal cell function of embryonic and adult tissues but that this gene is not a tumor suppressor for sporadic forms of breast cancer.
the TSG101 interaction with HRS is a crucial step in endocytic down-regulation of mitogenic signaling and this interaction may have a role in linking the functions of early and late endosomes
the Tsg101 protein has only weak oncogenic properties
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
, tumor susceptibility Gene-101
, Tumor Susceptibility Gene homolog family member (tsg-101)
, ESCRT-I complex subunit TSG101
, tumor susceptibility gene 101 protein
, tumor susceptibility protein 101
, tumor susceptibility gene 101
, tumor susceptibility gene 10
, tumor susceptibility protein
, Tumor supressor