anti-Tumor Susceptibility Gene 101 (TSG101) Antibodies

The protein encoded by TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. Additionally we are shipping TSG101 Proteins (13) and TSG101 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TSG101 7251 Q99816
TSG101 22088 Q61187
TSG101 292925 Q6IRE4
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Top anti-TSG101 Antibodies at antibodies-online.com

Showing 10 out of 133 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Hamster Mouse Un-conjugated ELISA, FACS, ICC, IF, IHC, IHC (p), IP, WB Detection of human TSG101 protein in HeLa whole cell lysate using ABIN152256. Western Blot: TSG101 Antibody (4A10) [ABIN152256] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with TSG101 antibody [4A10] diluted at 1:500. The signal was developed with Trident Sharp-ECL. 0.1 mL Log in to see 7 to 9 Days
$556.31
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-TSG101 Antibody Titration:  1.25ug/ml  Positive Control:  NIH/3T3 cell lysate Sample Type: mouse fibroblast lusate (10ug)Primary Dilution: 1:1000 (1% BSA)Secondary Dilution: 1:2000 (5% milk)Image Submitted By: Anonymous researcher . 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated IHC, WB Host:  Rabbit  Target Name:  TSG101  Sample Type:  Thymus tumor lysates  Antibody Dilution:  1.0ug/ml Rabbit Anti-TSG101 Antibody   Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic, nucleus Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TSG101 Antibody Titration:  2.5ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate TSG101 is supported by BioGPS gene expression data to be expressed in HepG2 WB Suggested Anti-TSG101 <br /> Antibody Titration: 2.5 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: HepG2 cell lysate <br /> TSG101 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: TSG101 Antibody  - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II. Western Blot: TSG101 Antibody  - Analysis in human cell line MCF-7. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TSG101 Antibody Titration:  2.5ug/ml  ELISA Titer:  1:62500  Positive Control:  NIH/3T3 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, ICC, IF, IHC, IHC (p), WB Flow Cytometry: TSG101 Antibody (JJ0900)  - Analysis of K562 cells with TSG101 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. Immunocytochemistry/Immunofluorescence: TSG101 Antibody (JJ0900)  - Staining TSG101 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 100 μL Log in to see 34 Days
$373.75
Details

Top referenced anti-TSG101 Antibodies

  1. Hamster Monoclonal TSG101 Primary Antibody for ELISA, FACS - ABIN152256 : Garrus, von Schwedler, Pornillos, Morham, Zavitz, Wang, Wettstein, Stray, Côté, Rich, Myszka, Sundquist: Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. in Cell 2001 (PubMed)
    Show all 66 Pubmed References

  2. Human Monoclonal TSG101 Primary Antibody for IF, IHC (p) - ABIN563269 : Skogberg, Gudmundsdottir, van der Post, Sandström, Bruhn, Benson, Mincheva-Nilsson, Baranov, Telemo, Ekwall: Characterization of human thymic exosomes. in PLoS ONE 2013 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal TSG101 Primary Antibody for ICC, IF - ABIN4363086 : Gross, Chaudhary, Bartscherer, Boutros: Active Wnt proteins are secreted on exosomes. in Nature cell biology 2012 (PubMed)
    Show all 2 Pubmed References

  4. Cow (Bovine) Polyclonal TSG101 Primary Antibody for IHC, WB - ABIN2780037 : Stefan, Claiborn, Stasiek, Chai, Ohta, Longnecker, Greally, Nicholls: Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes. in BMC genomics 2005 (PubMed)
    Show all 2 Pubmed References

  5. Mouse (Murine) Polyclonal TSG101 Primary Antibody for IF, IHC - ABIN5664008 : Yu, Yan, Yang, Wu, Ling, Chen, Tang, Tan, Cao, Wu, Yan, Wang: Platelets promote tumour metastasis via interaction between TLR4 and tumour cell-released high-mobility group box1 protein. in Nature communications 2014 (PubMed)

  6. Cow (Bovine) Polyclonal TSG101 Primary Antibody for WB - ABIN2780762 : Surjit, Oberoi, Kumar, Lal: Enhanced alpha1 microglobulin secretion from Hepatitis E virus ORF3-expressing human hepatoma cells is mediated by the tumor susceptibility gene 101. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against TSG101 Interaction Partners

Fruit Fly (Drosophila melanogaster) Tumor Susceptibility Gene 101 (TSG101) interaction partners

  1. loss of ept alters nuclear cell cycle control in developing imaginal discs and the DaPKC, presenilin, and rbf1 genes as modifiers of molecular and cellular phenotypes that result from loss of ept

  2. analysis of genetic interactions between the Drosophila tumor suppressor gene ept and the stat92E transcription factor

Human Tumor Susceptibility Gene 101 (TSG101) interaction partners

  1. The authors provide evidence that the ubiquitin (Ub) E2 variant domain of Tsg101 provides chaperone function to HIV-1 Gag that is independent of its interaction with the Pro-Thr-Ala-Pro motif, supporting the hypothesis that the domain provides a function in addition to its well-established role in cellular endosomal sorting complex required for transport factor recruitment.

  2. In this review, HIV-infected cells have TSG101 on their surface and thus can be used in antibody-based therapies. The development of a monoclonal antibody CB8-2 lessens the assembly of viruses from infected cells

  3. Results indicate that Vpr overcomes the effects of TSG101 overexpression to support viral production by competing with TSG101 to bind Gag.

  4. our studies reveal that Tsg101 plays a role in the trafficking of macropinocytosed Kaposi's sarcoma-associated herpesvirus in the endothelial cells

  5. Knockdown of LAMP2A, a CMA-related protein, and TSG101, an mA-related protein, significantly but only partially decreased the punctate accumulation of GAPDH (show GAPDH Antibodies)-HT in AD293 cells and primary cultured rat cortical neurons.

  6. the variant alleles of TSG101 rs2292179 and ATF2 (show ATF2 Antibodies) rs3845744 were associated with a reduced risk of breast cancer, particularly for subjects with BMI <24 (kg/m(2)) and postmenopausal women, respectively

  7. TSGDelta154-1054 splice variant increases TSG101 oncogenicity by inhibiting its E3-ligase-mediated proteasomal degradation.

  8. Results show that TSG101 bidirectionally modulates cell invasion through regulating MMP-9 (show MMP9 Antibodies) mRNA expression in different cell types.

  9. TSG101 plays an important role in the development of hepatocellular carcinoma

  10. Expression of tsg101 mRNA and of TSG101 protein were significantly higher in the oxaliplatin resistant cell line than parent HT-29 cels.

Mouse (Murine) Tumor Susceptibility Gene 101 (TSG101) interaction partners

  1. Tsg101 was deleted from mature oligodendroglia in vivo. This resulted in severe spongiform encephalopathy, histopathologically similar to that observed in Mgrn1 (show MGRN1 Antibodies) null mutant mice but with a more rapid onset.

  2. BLOS1 (show BLOC1S1 Antibodies) interacts with sorting nexin 2 (show SNX2 Antibodies) and the ESCRT-I (show VPS28 Antibodies) component TSG101 to mediate the sorting of EGFR (show EGFR Antibodies) into endosomal compartments

  3. pigment-type switching likely requires MGRN1's ubiquitin ligase activity but not its ability to bind TSG101 or NEDD4.

  4. Tsg101 has a role in expression of EGFR (show EGFR Antibodies) and ErbB2 (show ERBB2 Antibodies) and preventing induction of autophagy prior to cell death

  5. show that ubiquitin recognition by TSG101 is required for cSMAC formation, T cell receptor (TCR) microcluster signal termination, TCR downregulation.

  6. Negative regulation of cell growth and differentiation by TSG101 through association with p21(Cip1/WAF1 (show CDKN1A Antibodies)).

  7. Targeted deletion results in cell cycle arrest and p53 (show TP53 Antibodies)-independent cell death

  8. our results suggest that Tsg101 is required for normal cell function of embryonic and adult tissues but that this gene is not a tumor suppressor for sporadic forms of breast cancer.

  9. the TSG101 interaction with HRS is a crucial step in endocytic down-regulation of mitogenic signaling and this interaction may have a role in linking the functions of early and late endosomes

  10. the Tsg101 protein has only weak oncogenic properties

TSG101 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

Gene names and symbols associated with TSG101

  • tumor susceptibility 101 (TSG101) antibody
  • Tumor susceptibility gene 101 (TSG101) antibody
  • Tumor Susceptibility Gene homolog (tsg-101) antibody
  • tumor susceptibility 101 (tsg101) antibody
  • tumor susceptibility gene 101 (Tsg101) antibody
  • tumor susceptibility gene 101 (TSG101) antibody
  • tumor susceptibility 101 (Tsg101) antibody
  • tumor susceptibility 101a (tsg101a) antibody
  • tumor susceptibility 101 L homeolog (tsg101.L) antibody
  • AI255943 antibody
  • burs antibody
  • CC2 antibody
  • CG9712 antibody
  • Dmel\\CG9712 antibody
  • DmTSG101 antibody
  • dTsg101 antibody
  • dVps23 antibody
  • ept antibody
  • ESCRT-I antibody
  • MGC76193 antibody
  • Rw antibody
  • TSG10 antibody
  • TSG101 antibody
  • VPS23 antibody
  • zgc:86926 antibody

Protein level used designations for TSG101

CG9712-PA , TSG101-PA , erupted , tumor susceptibility Gene-101 , Tumor Susceptibility Gene homolog family member (tsg-101) , ESCRT-I complex subunit TSG101 , tumor susceptibility gene 101 protein , tumor susceptibility protein 101 , tumor susceptibility gene 101 , tumor susceptibility gene 10 , tumor susceptibility protein , Tumor supressor

GENE ID SPECIES
100057099 Equus caballus
39881 Drosophila melanogaster
182474 Caenorhabditis elegans
693787 Macaca mulatta
451065 Pan troglodytes
394879 Xenopus (Silurana) tropicalis
100172234 Pongo abelii
7251 Homo sapiens
22088 Mus musculus
423082 Gallus gallus
485406 Canis lupus familiaris
507659 Bos taurus
292925 Rattus norvegicus
415179 Danio rerio
446571 Xenopus laevis
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