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This intronless gene encodes a carcinoma-associated antigen. Additionally we are shipping TACSTD2 Antibodies (172) and TACSTD2 Kits (3) and many more products for this protein.
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The results suggest that TROP2 expression could be an effective prognostic biomarker for oral squamous cell carcinoma
TROP-2, SLP-2 and CD56 (show NCAM1 Proteins) were effective diagnostic markers for PTC (show F9 Proteins), especially when they were combined to use.
Trop2 has a potential role in the promotion of EMT (show ITK Proteins) in BC.
these results suggested that TROP2 may promote osteosarcoma cell proliferation and migration via PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling and may serve as a novel treatment target for osteosarcoma .
TACSTD2 downregulation is associated with hepatocellular carcinoma.
findings demonstrate that a membranous TROP-2 staining pattern is highly specific for PTC (show F9 Proteins), which may serve as a potential diagnostic marker aiding in the accurate classification of morphologically equivocal thyroid follicular-patterned lesions
TROP2 promoted the proliferation, migration and metastasis of gallbladder cancer cells by regulating PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) pathway and inducing EMT (show ITK Proteins).
The results from clinical specimens showed that Trop2 expression correlated with MMP2 (show MMP2 Proteins) expression in primary thyroid cancer. The current study suggests that elevated expression of Trop2 may represent an important molecular hallmark that is biologically and clinically relevant to the progression of thyroid cancer.
these results suggest a differential role for TROP2 in different lung cancer subtypes
Results show that TROP2 expression is up-regulated in gastric tumor and its co-expression with AREG (show AREG Proteins) protein is associated with TNM (show ODZ1 Proteins) stage, tumor size, lymph node metastases, and distant metastases.
studies have begun to identify the mechanisms underlying TROP2's functions, including regulated intramembrane proteolysis or specific interactions with integrin b1 and claudin proteins.
Trop2 is a regulator of self-renewal, proliferation, and transformation
TROP2 modulates the interaction between the cells and matrix and regulates the formation of the ureteric duct by suppressing branching from the trunk during kidney development.
these results uncover a role for Trop2 loss in tumorigenesis and the mesenchymal transdifferentiation observed in a subset of squamous cell carcinomas.
In human and mouse, Trop2 is highly expressed at both the transcript and protein levels on several essential normal tissues.
Study also provides the first indication of a molecular signaling pathway activated by Trop2 which has important implications for cancer cell growth and survival.
Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics.
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.
40kD glycoprotein, identified by monoclonal antibody GA733
, cell surface glycoprotein TROP2
, cell surface glycoprotein Trop-2
, epithelial glycoprotein-1
, gastrointestinal tumor-associated antigen GA7331
, membrane component chromosome 1 surface marker 1
, membrane component, chromosome 1, surface marker 1
, pancreatic carcinoma marker protein GA733-1
, pancreatic carcinoma marker protein GA7331
, lymphocyte antigen 97
, tunor-associated calcium signal transducer 2
, parturition-related protein 1
, tumor-associated calcium signal transducer 2
, tumor associated calcium signal transducer 2