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anti-Tyrosine-Protein Phosphatase Non-Receptor Type 4 (PTPN4) Antibodies

The protein encoded by PTPN4 is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping Tyrosine-Protein Phosphatase Non-Receptor Type 4 Kits (10) and Tyrosine-Protein Phosphatase Non-Receptor Type 4 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTPN4 5775 P29074
PTPN4 19258 Q9WU22
PTPN4 246116  
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Top anti-Tyrosine-Protein Phosphatase Non-Receptor Type 4 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cells, using PTPN4 antibody. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using PTPN4 antibody (ABIN5972222) at 1/1000 dilution. 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunofluorescent staining of human cell line U-2 OS shows localization to nucleus & cytosol. Antibody staining is shown in green. Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney shows strong cytoplasmic and membranous positivity in renal tubules. 100 μL 11 to 12 Days
$637.32
Details
Human Mouse Un-conjugated ELISA, WB   100 μg 11 to 14 Days
$537.17
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated ICC, ELISA, WB   100 μL 11 to 14 Days
$551.83
Details
Human Chicken Un-conjugated ELISA, WB   50 μg 11 to 16 Days
$579.86
Details
Human Rabbit Un-conjugated IHC, WB   100 μL 11 to 16 Days
$743.29
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL 11 to 16 Days
$454.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μg 13 to 16 Days
$380.00
Details

More Antibodies against Tyrosine-Protein Phosphatase Non-Receptor Type 4 Interaction Partners

Human Tyrosine-Protein Phosphatase Non-Receptor Type 4 (PTPN4) interaction partners

  1. Study identified a nonsense mutation of PTPN4 with mutation ratio of 90.90% from 1 case of rectal cancer. Overexpression of PTPN4 suppressed the growth of colorectal cancer cells. PTPN4 dephosphorylates pSTAT3 at the Tyr705 residue with a direct interaction and depresses the transcriptional activity of STAT3.

  2. Data show that mutations affect the regulation of the protein tyrosine phosphatase non-receptor type 4 (PTPN4) bidomain and indicate that the PDZ-PDZ ligand regulation of PTPN4 is a linker-mediated mechanism.

  3. Binding assays confirmed that three (Cyto8-mtxd-1, Cyto8-mtxk-4 and Cyto8-mtxd-1k-4) out of the five designed peptides exhibit moderately or considerably increased affinity as compared to the native peptide Cyto8-RETEV

  4. the p38gamma.PTPN4 interaction promotes cellular signaling, preventing cell death induction.

  5. Deletion of PTPN4 has been reported in monozygotic twins with a Rett syndrome-like phenotype.

  6. The physiologically active PTPN4 two-domain (the PDZ and the phosphatase domains) adopts a predominant compact conformation in solution. PDZ ligand binding restores the catalytic competence of PTPN4 disrupting the transient interdomain communication.

  7. These findings suggest that PTPN4 negatively regulates cell proliferation and motility through dephosphorylation of CrkI.

  8. PTPN4 is dispensable for T cell development and/or T cell effector functions.

Mouse (Murine) Tyrosine-Protein Phosphatase Non-Receptor Type 4 (PTPN4) interaction partners

  1. our results provide new insight into the TLR4 pathway and identify PTPN4 as a specific inhibitor of TRIF-dependent TLR4 pathway.

  2. Tyrosine dephosphorylation events regulated by PTPMEG are important for both motor learning and cerebellar synaptic plasticity.

  3. PTPN3 and PTPN4 are dispensable for TCR signal transduction.

Tyrosine-Protein Phosphatase Non-Receptor Type 4 (PTPN4) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.

Gene names and symbols associated with PTPN4

  • protein tyrosine phosphatase, non-receptor type 4 (PTPN4) antibody
  • protein tyrosine phosphatase, non-receptor type 4 (Ptpn4) antibody
  • tyrosine-protein phosphatase non-receptor type 4 (CpipJ_CPIJ003699) antibody
  • tyrosine-protein phosphatase non-receptor type 4 (Tsp_12341) antibody
  • tyrosine-protein phosphatase non-receptor type 4 (Tsp_14272) antibody
  • protein tyrosine phosphatase, non-receptor type 4a (ptpn4a) antibody
  • hPTP-MEG antibody
  • MEG antibody
  • Ptn4 antibody
  • PTPMEG antibody
  • PTPMEG1 antibody
  • ptpn4 antibody
  • si:busm1-37o5.1 antibody
  • si:dz37o5.1 antibody
  • TEP antibody
  • TEP/mPTPMEG antibody

Protein level used designations for PTPN4

PTPase-MEG1 , megakaryocyte phosphatase , megakaryocyte protein-tyrosine phosphatase , protein tyrosine phosphatase MEG1 , protein-tyrosine phosphatase MEG1 , tyrosine-protein phosphatase non-receptor type 4 , testis-enriched protein tyrosine phosphatase , protein tyrosine phosphatase non-receptor type 4 , protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)

GENE ID SPECIES
5775 Homo sapiens
19258 Mus musculus
6035309 Culex quinquefasciatus
10900222 Trichinella spiralis
10907286 Trichinella spiralis
368448 Danio rerio
246116 Rattus norvegicus
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