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Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Additionally we are shipping B3GNT6 Proteins (8) and many more products for this protein.
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Human Polyclonal B3GNT6 Primary Antibody for WB - ABIN531224
Radhakrishnan, Grandgenett, Mohr, Bunt, Yu, Chowdhury, Hollingsworth: Expression of core 3 synthase in human pancreatic cancer cells suppresses tumor growth and metastasis. in International journal of cancer. Journal international du cancer 2013
expression was markedly down-regulated in gastric and colorectal carcinomas
alpha2beta1 integrin acquired core3 O-glycans in cells expressing core3 synthase with decreased maturation of beta1 integrin, leading to decreased levels of the alpha2beta1 integrin complex
Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs (By similarity).
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
, beta-1,3-N-acetylglucosaminyltransferase 6
, beta-1,3-N-acetylglucosaminyltransferase protein
, core 3 synthase