anti-UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3) Antibodies

GALNT3 encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. Additionally we are shipping GALNT3 Proteins (9) and GALNT3 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GALNT3 14425 P70419
GALNT3 2591 Q14435
GALNT3 366061  
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Top anti-GALNT3 Antibodies at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of MCF-7 cells using GALNT3 Antibody (Center) Cat.-No AP51768PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human skin tissue reacted with GALNT3 Antibody (Center) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of GALNT3 Antibody (Center) (ABIN653156) in MCF-7 cell line lysates (35 µg/lane). GALNT3 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skin tissue reacted with GALNT3 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of GALNT3 Antibody in MCF-7 cell line lysates (35ug/lane) Formalin-fixed and paraffin-embedded human skin tissue reacted with GALNT3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using GALNT3 antibody (ABIN5973963) at 1/1000 dilution. 100 μL Log in to see 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using GALNT3 antibody. 200 μL Log in to see 12 to 14 Days
$438.90
Details
Human Mouse Un-conjugated WB Western Blot analysis of GALNT3 expression in transfected 293T cell line by GALNT3 MaxPab polyclonal antibody.Lane 1: GALNT3 transfected lysate(15.51 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 11 to 12 Days
$348.04
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using GALNT3 antibody. 100 μL Log in to see 16 Days
$366.77
Details
Human Rabbit Un-conjugated WB Western Blot analysis of GALNT3 expression in transfected 293T cell line by GALNT3 MaxPab polyclonal antibody.Lane 1: GALNT3 transfected lysate(15.90 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 11 to 12 Days
$337.50
Details

More Antibodies against GALNT3 Interaction Partners

Mouse (Murine) UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3) interaction partners

  1. role of GALNT3 in regulating host responses during influenza A virus infection

  2. Overexpression of Galnt3 in chondrocytes causes dwarfism due to the increase of mucin-type O-glycans and a reduction in chondroitin sulfates.

  3. The stabilized Fgf23-Autosomal dominant hypophosphatemic rickets allele reversed the Galnt3-null phenotype and normalized total Fgf23, serum phosphorus, and bone Fgf23 mRNA.

  4. The deficiency of Galnt3 results in a severe reduction of mucin-type O-glycans in spermatids and causes impaired acrosome formation, leading to oligoasthenoteratozoospermia, and Galnt3 may also be involved in the process of fertilization.

  5. A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis.

  6. dietary phosphate restriction normalizes biochemical and skeletal phenotypes of Galnt3 knockout mice and, thus, can be an effective therapy for tumoral calcinosis.

  7. The expression levels of murine ppGalNAc-Ts (mGalNAc-Ts), T1, T2, T3, T4, T6, and T7 were compared between mouse colon carcinoma colon 38 cells and variant SL4 cells, selected for their metastatic potentials.

  8. Galnt3-deficient mice have a biochemical phenotype of tumoral calcinosis and provide in vivo evidence that Galnt3 plays an essential role in proper secretion of Fgf23 in mice.

Human UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3) interaction partners

  1. GalNAc-T3 was highly expressed by motile spermatozoa and the expression correlated positively with the classical semen parameters.

  2. Study shows that ZEB2 negatively regulates a GalNAc-transferase (GALNT3) that is involved in O-glycosylation adds another layer of complexity to the role of ZEB2 in cancer progression and metastasis.

  3. Giantin-knockout zebrafish exhibit hyperostosis and ectopic calcium deposits, recapitulating phenotypes of hyperphosphatemic familial tumoral calcinosis, a disease caused by mutations in GALNT3. These data reveal a new feature of Golgi homeostasis: the ability to regulate glycosyltransferase expression to generate a functional proteoglycome.

  4. study supports an essential role of GALNT3 in Epithelial ovarian cancer dissemination, including its implication in modulating post-translational modifications and EOC metabolism

  5. The acetylated residues on ppGalNAc-T3 function as control points for enzyme activity, and high level of GlcNAc glycosides promote a synergistic regulatory mechanism, leading to a metabolically disordered state.

  6. This study identified GALNT3 as a novel gene that rendered patients susceptible to coronary artery disease (CAD), and the A allele of a disease-associated variant rs4621175 linked reduced CAD risk through decreased GALNT3 expression.

  7. Study indicates that loss of GALNT3 occurs in poorly differentiated PDAC, which is associated with the increased aggressiveness and altered glycosylation of ErbB family proteins.

  8. The presence of lectin domain T3lec or T4lec during ppGalNAc-T2 and ppGalNAc-T3 catalytic reaction had a clear inhibitory effect on GalNAc-T activity.

  9. GalNAc-T3 might play a role in the pathogenesis of early stage oral squamous cell carcinoma recurrence

  10. MGAT5 expression is a potential independent adverse prognostic biomarker for recurrence and survival of patients with ccRCC after nephrectomy.

  11. Two microRNAs (miRNAs), miR-17-3p and miR-221, which target GalNAc transferase 3 (GALNT3) mRNA, are rapidly downregulated in human alveolar basal epithelial cells during the early stage of influenza A virus infection.

  12. hyperphosphatemic familial tumoral calcinosis and hyperphosphatemic hyperostosis syndrome caused by a novel GALNT3 mutation

  13. Polymorphisms of rs1863196, rs6710518, rs4667492, rs1349321 and rs6721582 (GALNT3) are associated with bone mineral density.GALNT3 may play a role in genetic susceptibility to postmenopausal osteoporosis in Chinese womeh.

  14. Data are indicative for a strong oncogenic potential of the GALNT3 gene in advanced EOC and identify this transferase as a novel EOC biomarker.

  15. Our data suggest that GalNAc-T3 expression may be a useful indicator of tumor differentiation in thyroid carcinomas.

  16. we integrated different computational tools to perform the in silico analysis of clinically significant mutations (nsSNPs/single amino acid change) at both functional and structural levels, found in human GALNT3, GALNT8, GALNT12, and GALNT13 genes.

  17. GalNac transferase transgenic knock-out mice neurons have significantly increased rates of axon degeneration.

  18. N-acetylgalactosaminyltransferases-3 expression independently predicts high-grade tumour and poor prognosis in patients with renal cell carcinomas.

  19. a novel homozygous missense mutation affecting highly conserved amino acids in GALNT3 in patients with hyperphosphatemic familial tumoral calcinosis

  20. GalNAc-T3 is likely involved in pancreatic carcinogenesis

GALNT3 Antigen Profile

Protein Summary

This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities.

Gene names and symbols associated with GALNT3

  • polypeptide N-acetylgalactosaminyltransferase 3 (Galnt3) antibody
  • polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3) antibody
  • GalNAc-T3 antibody
  • HFTC antibody
  • HHS antibody

Protein level used designations for GALNT3

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 , galNAc-T3 , polypeptide GalNAc transferase 3 , polypeptide N-acetylgalactosaminyltransferase 3 , pp-GaNTase 3 , ppGaNTase-T3 , protein-UDP acetylgalactosaminyltransferase 3 , GalNAc transferase 3 , polypeptide GalNAc-transferase T3

GENE ID SPECIES
14425 Mus musculus
2591 Homo sapiens
366061 Rattus norvegicus
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