anti-UL16 Binding Protein 2 (ULBP2) Antibodies

Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. Additionally we are shipping ULBP2 Kits (27) and ULBP2 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ULBP2 80328 Q9BZM5
ULBP2    
ULBP2    
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Top anti-ULBP2 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), ELISA Immunochemical staining of human ULBP2 in human renal-carcinoma with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixtur 100 μg Log in to see 14 to 16 Days
$218.90
Details
Human Rabbit Un-conjugated WB ULBP2 Antibody (Center)  western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the ULBP2 antibody detected the ULBP2 protein (arrow). Western blot analysis of ULBP2 (arrow) using rabbit polyclonal ULBP2 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ULBP2 gene. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western Blot at 1:1000 dilution Lane 1: HT-1080 whole cell lysate Lane 2: U-251 MG whole cell lysate Lysates/proteins at 20 ug per lane. Western blot analysis of ULBP2 using rabbit polyclonal ULBP2 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ULBP2 gene. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC (p) Immunochemical staining of human ULBP2 in human gastric cancer with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of human ULBP2 in human hepatoma with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 14 to 16 Days
$273.90
Details
Human Rabbit Un-conjugated WB Western blot analysis of extract of mouse ovary and rat ovary cells, using ULBP2 antibody. 100 μL Log in to see 16 Days
$366.77
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 13 to 16 Days
$386.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 14 to 16 Days
$273.90
Details
Mouse Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using ULBP2 antibody. 200 μL Log in to see 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated WB Western blot analysis of ULBP2 expression in mouse ovary (A), rat ovary (B) whole cell lysates. 100 μL Log in to see 11 to 18 Days
$369.55
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details

More Antibodies against ULBP2 Interaction Partners

Human UL16 Binding Protein 2 (ULBP2) interaction partners

  1. High ULBP2 expression is associated with lymphoma.

  2. IMP3 directly interacts with ULBP2 mRNA, leading to ULBP2 transcript destabilization and reduced ULBP2 surface expression and indirectly downregulates MICB with a mechanism functionally distinct from that of ULBP2.

  3. By suppressing AR and up-regulating ULBP2 in HCC, cisplatin could up-regulate cytotoxicity of NK cells to better target HCC.

  4. human tumor cells lost their surface expression of ULBP2, but not ULBP1 and ULBP3, during NK cell-mediated cytolysis.

  5. This study suggests that NKG2D ligands shedding of MICA, MICB and ULBP-2 is a novel pathway in endometriosis complex pathogenesis that impairs Natural Killer Cells cell function.

  6. Varicella-Zoster Virus differentially modulates expression of the NKG2D ligands by upregulating MICA expression and reducing ULBP2 and ULBP3 expression in the infected cells.

  7. A conserved WW domain-like motif regulates CD74 antigen-dependent cell-surface transport of the NKG2D ligand ULBP2.

  8. NKG2D and NKG2DL are involved in allergen-induced activation of dendritic epidermal T cells and the NKG2D/NKG2DL pathway might be a potential target for treatment of contact hypersensitivity.

  9. Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.

  10. Data inticate that heat shock protein 60 (HSP60) interacted constitutively with NKG2D ligand ULBP2 and phosphatase of regenerating liver 3 (PRL-3) regulated HSP60 tyrosine phosphorylation.

  11. Results suggest that ULBP2 is expressed and released from cervical cancer cells by CRF, which regulates NKG2D expression in natural killer cells.

  12. c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells.

  13. the NKG2D ligand ULBP2 is transported to the cell surface through an endosomal pathway dependent on protein kinase C and lysosomal integrity. ULBP2 surface transport is dependent on the invariant chain.

  14. This study provides for the first time, the c-Myc dependent regulation of NKG2D ligands, ULBP1/2/3 in acute myeloid leukemia.

  15. Vpr augments ULBP2 expression on both infected and uninfected bystander cells during HIV-1 infection of primary CD4+ T lymphocytes.

  16. Study shows that tumor-suppressive miR-34a and miR-34c act as ULBP2 repressors. Findings also implicate p53 in ULBP2 regulation, emphasizing the role of the specific NKG2DL in tumor immune surveillance.

  17. Data show that VSV infection caused an active suppression of NKG2D-ligand surface expression, affecting both endogenous and histone deacetylase (HDAC)-inhibitor induced MICA, MICB and ULBP-2 expression.

  18. Findings define the involvement of p53 in the regulation of ULBP1 and ULBP2 which enhance NK cell-mediated target recognition.

  19. analysis of the area under receiver operating characteristic curves showed that ULBP2 was superior to CA 19-9 in discriminating patients with early-stage PC from healthy controls

  20. The human NKG2D ligand ULBP2 can be expressed at the cell surface with or without a GPI anchor and both forms can activate NK cells

ULBP2 Antigen Profile

Protein Summary

Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis- Golgi apparatus so that it does not reach the cell surface.

Gene names and symbols associated with ULBP2

  • UL16 binding protein 2 (ULBP2) antibody
  • NKG2D ligand 2-like (LOC100355436) antibody
  • N2DL2 antibody
  • RAET1H antibody

Protein level used designations for ULBP2

ALCAN-alpha , N2DL-2 , NKG2D ligand 2 , NKG2DL2 , UL16-binding protein 2 , retinoic acid early transcript 1 H , retinoic acid early transcript 1H

GENE ID SPECIES
80328 Homo sapiens
100355436 Oryctolagus cuniculus
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