URI1, Prefoldin-Like Chaperone Proteins (URI1)

This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22.

• URI1 prefoldin-like chaperone L homeolog (uri1.L)
• URI1, prefoldin like chaperone (URI1)

• C19orf2 protein
• NNX3 protein
• PPP1R19 protein
• RMP protein
• URI protein

RNA polymerase II subunit 5-mediating protein , RPB5-mediating protein , protein phosphatase 1 regulatory subunit 19 , protein phosphatase 1, regulatory subunit 19 , unconventional prefoldin RPB5 interactor 1