anti-Ubiquitin Specific Peptidase 17-Like 2 (USP17L2) Antibodies

Deubiquitinating enzyme that specifically removes conjugated ubiquitin from CDC25A, thereby playing a key role in cell cycle regulation. Additionally we are shipping USP17L2 Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP17L2 377630 Q6R6M4
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Top anti-USP17L2 Antibodies at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-USP17L2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart WB Suggested Anti-USP17L2 Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Mouse Un-conjugated ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) . Dilution: 1:500~1000 Detection limit for recombinant GST tagged DUB3 is approximately 0.3ng/ml as a capture antibody. 100 μg Log in to see 8 to 11 Days
$527.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB USP17L2 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the USP17L2 antibody detected the USP17L2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB Western Blot: Dub3 Antibody [NBP1-79745] - Human Heart lysate, concentration 0.2-1 ug/ml. 20 μL Log in to see 8 to 11 Days
$233.06
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged DUB3 is approximately 0.3ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated FACS, WB   400 μL Log in to see 11 to 14 Days
$463.83
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 6 to 8 Days
$491.70
Details

More Antibodies against USP17L2 Interaction Partners

Human Ubiquitin Specific Peptidase 17-Like 2 (USP17L2) interaction partners

  1. Dub3 is identified as a bona fide Snail1 deubiquitinase, which interacts with and stabilizes Snail1.

  2. these data identify DUB3 and USP7 as factors that regulate DNA replication by controlling Geminin protein stability, and suggest that USP7 may be involved in Geminin dysregulation during breast cancer progression.

  3. We provide evidence that DUB3 proteins regulate YAP/TAZ activity by controlling the stability of the E3 ligase ITCH, the LATS kinases and the AMOT family proteins. As a novel Hippo pathway regulator, DUB3 has the potential to act a tumor suppressor by limiting YAP activity.

  4. In cigarette smoke extract-exposed airway epithelial cells and macrophages, HDAC2 is excessively ubiquitinated and degraded in the proteasome attributed to low expression of USP17.

  5. These data indicate that the Dub3 might be a valuable biomarker for the prediction of ovarian cancer prognosis and Dub3 inhibition might be a potential strategy for ovarian cancer treatment.

  6. Dub3 counteracts H2AX E3 ligases RNF8 and RNF168. Moreover, Dub3 and H2AX interact and Dub3 deubiquitinates H2AX in vitro.

  7. Recently, much progress has been made in understanding the physiological functions of cytokine-inducible DUBs such as DUB-1, DUB-2, and DUB-3/USP17, in regulation of cell proliferation and apoptosis in lymphocytes. [review]

  8. As a major regulator of Cdc25A, Dub3 is an example of a transforming ubiquitin hydrolase that subverts a key component of the cell cycle machinery, promoting oncogenic transformation.

  9. human DUB-3, like the murine DUB family members, is transiently induced in response to cytokines and can, when constitutively expressed, block growth factor-dependent proliferation.

  10. Identifies DUB3 as being one of 30 genes with the most variable copy numbers in three human genomes.

USP17L2 Antigen Profile

Protein Summary

Deubiquitinating enzyme that specifically removes conjugated ubiquitin from CDC25A, thereby playing a key role in cell cycle regulation. Deubiquitination of CDC25A prevents its degradation by the proteasome during the G1/S and G2/M phases of the cell cycle and is required for cell-cycle progression. Has transforming capabilities on cell lines. May also function in cell apoptosis.

Gene names and symbols associated with USP17L2

  • ubiquitin specific peptidase 17-like family member 2 (USP17L2) antibody
  • ubiquitin carboxyl-terminal hydrolase 17 (LOC695235) antibody
  • DUB-3 antibody
  • DUB3 antibody
  • USP17 antibody

Protein level used designations for USP17L2

deubiquitinating enzyme 17-like protein 2 , deubiquitinating enzyme 3 , deubiquitinating protein 3 , ubiquitin carboxyl-terminal hydrolase 17 , ubiquitin carboxyl-terminal hydrolase 17-like protein 2 , ubiquitin specific peptidase 17-like 2 , ubiquitin thioesterase 17-like protein 2 , ubiquitin thiolesterase 17-like protein 2 , ubiquitin-specific-processing protease 17-like protein 2

GENE ID SPECIES
377630 Homo sapiens
695235 Macaca mulatta
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