anti-Ubiquitin Specific Peptidase 22 (USP22) Antibodies

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Additionally we are shipping USP22 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP22 23326 Q9UPT9
USP22 216825 Q5DU02
USP22 303201  
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Top anti-USP22 Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-USP22 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human heart Host: Rabbit  <br /> Target Name: USP22  <br /> Sample Tissue: Human Fetal Lung <br /> Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-USP22 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of USP22 Antibody (C-term) (ABIN388914) in Jurkat cell line lysates (35 µg/lane). USP22 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of USP22 Antibody (N-term) (ABIN388913) in Jurkat cell line lysates (35 µg/lane).USP22(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated WB USP22 Antibody (C-term) (ABIN1882289) western blot analysis in Daudi cell line lysates (35 µg/lane). This demonstrates the USP22 antibody detected the USP22 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), SimWes, WB   0.1 mL Log in to see 7 to 9 Days
$444.19
Details
Chicken Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

USP22 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-USP22 Antibodies

  1. Human Monoclonal USP22 Primary Antibody for WB - ABIN1882289 : Bechtel, Rosenfelder, Duda, Schmidt, Ernst, Wellenreuther, Mehrle, Schuster, Bahr, Blöcker, Heubner, Hoerlein, Michel, Wedler, Köhrer, Ottenwälder, Poustka, Wiemann, Schupp: The full-ORF clone resource of the German cDNA Consortium. in BMC genomics 2008 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal USP22 Primary Antibody for IHC (p), SimWes - ABIN4364565 : Schrecengost, Dean, Goodwin, Schiewer, Urban, Stanek, Sussman, Hicks, Birbe, Draganova-Tacheva, Visakorpi, DeMarzo, McMahon, Knudsen: USP22 regulates oncogenic signaling pathways to drive lethal cancer progression. in Cancer research 2014 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal USP22 Primary Antibody for IHC (p), WB - ABIN388914 : Wang, Zhu, Guo, Wang, Yang: Decreased H2B monoubiquitination and overexpression of ubiquitin-specific protease enzyme 22 in malignant colon carcinoma. in Human pathology 2015 (PubMed)

  4. Human Polyclonal USP22 Primary Antibody for WB - ABIN388913 : Hong, Lee, Chung: Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination. in Journal of cellular physiology 2015 (PubMed)

More Antibodies against USP22 Interaction Partners

Human Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. Data provided evidence that USP22, an up-stream molecule of AP4 (show REPIN1 Antibodies), exhibits strong potential to promote colorectal cancer (CRC (show CALR Antibodies)) metastasis, particularly CRC (show CALR Antibodies) migration and invasion capacities, both in vitro and in vivo, by inducing EMT (show ITK Antibodies) via AP4 (show REPIN1 Antibodies) activating. Moreover, USP22 and AP4 (show REPIN1 Antibodies) overexpression may stimulate tumor metastasis and adversely affect overall survival in CRC (show CALR Antibodies) patients.

  2. Cancer stem cells marker USP22 influences drug sensitivity via regulating SIRT1 (show SIRT1 Antibodies), which will shed new insights into the mechanisms of multidrug resistance in hepatocellular carcinoma .

  3. our study demonstrates that USP22 is indispensable for gastric cancer stem cell self-renewal through stabilization of BMI1 (show BMI1 Antibodies).

  4. Downregulation of USP22 in ATC (show SRPK1 Antibodies) cells impeded tumor growth and lung metastasis in vivo.

  5. Studies indicate that aberrant expression of the Ubiquitin-Specific Peptidase 22 (USP22) has been associated with poor cancer prognosis.

  6. we demonstrated that USP22 was highly expressed in OS tissues and cells lines. Downregulation of USP22 inhibited OS cell proliferation, invasion, and EMT (show ITK Antibodies) in vitro. In addition, downregulation of USP22 suppressed OS tumor growth and metastasis in vivo.

  7. In breast cancer cell lines USP22 increases c-Myc (show MYC Antibodies) stability through c-Myc (show MYC Antibodies) deubiquitination, which is closely correlated with breast cancer progression.

  8. that nuclear GSK3beta- and USP22-mediated KDM1A (show KDM1A Antibodies) stabilization is essential for glioblastoma tumorigenesis

  9. findings suggest that USP22 may be involved in hepatocellular carcinoma progression in cooperation with survivin (show BIRC5 Antibodies).

  10. These findings provide evidence that high USP22 expression might be important in tumor progression and serves as an independent molecular marker for poor hepatocellular carcinoma prognosis

Mouse (Murine) Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. Usp22 is the first deubiquitinase reported to regulate both V(D)J recombination and class switch recombination in vivo by facilitating classical non-homologous end joining.

  2. high D-glucose induces increased expression of USP22 in cultured podocytes and diabetic rats. USP22 inhibition confers a protective effect against high glucose-induced podocyte depletion, apoptosis and inflammation.

  3. that nuclear GSK3beta- and USP22-mediated KDM1A (show KDM1A Antibodies) stabilization is essential for glioblastoma tumorigenesis

  4. Usp22 deficiency impairs intestinal epithelial lineage specification.

  5. USP22 is a transcriptional repressor of the locus encoding the core pluripotency factor sex-determining region Y-box 2 (SOX2 (show SOX2 Antibodies)) in embryonic stem cells.

  6. Genetic deletion of the usp22 gene results in Sirt1 (show SIRT1 Antibodies) instability, elevated p53 (show TP53 Antibodies) transcriptional activity and early embryonic lethality.

USP22 Antigen Profile

Protein Summary

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators, where it is required for transcription (By similarity).

Gene names and symbols associated with USP22

  • ubiquitin specific peptidase 22 (USP22) antibody
  • ubiquitin specific peptidase 22 (Usp22) antibody
  • ubiquitin specific peptidase 22 (usp22) antibody
  • ubiquitin specific peptidase 22 S homeolog (usp22.S) antibody
  • AI427806 antibody
  • usp3l antibody
  • usp22 antibody
  • usp22 b antibody
  • usp22-a antibody
  • usp22-B antibody
  • zgc:136342 antibody

Protein level used designations for USP22

deubiquitinating enzyme 22 , ubiquitin carboxyl-terminal hydrolase 22 , ubiquitin specific protease 22 , ubiquitin thioesterase 22 , ubiquitin thiolesterase 22 , ubiquitin-specific processing protease 22 , ubiquitin-specific-processing protease 22 , ubiquitin specific peptidase 22 , ubiquitin carboxyl-terminal hydrolase 22-like , Deubiquitinating enzyme 22-B , Ubiquitin thioesterase 22-B , Ubiquitin-specific-processing protease 22-B , deubiquitinating enzyme 22 B , ubiquitin carboxyl-terminal hydrolase 22-B , ubiquitin specific peptidase 22 b , ubiquitin thioesterase 22 B , ubiquitin thiolesterase 22-B , ubiquitin-specific-processing protease 22 B

GENE ID SPECIES
23326 Homo sapiens
216825 Mus musculus
303201 Rattus norvegicus
609588 Canis lupus familiaris
692275 Danio rerio
712098 Macaca mulatta
100053238 Equus caballus
100340977 Oryctolagus cuniculus
100379835 Xenopus (Silurana) tropicalis
100456449 Pongo abelii
100476428 Ailuropoda melanoleuca
454511 Pan troglodytes
509694 Bos taurus
100729060 Cavia porcellus
779144 Xenopus laevis
Selected quality suppliers for anti-USP22 (USP22) Antibodies
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