anti-Ubiquitin Specific Peptidase 30 (Usp30) Antibodies

USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).[supplied by OMIM, Dec 2008].. Additionally we are shipping Usp30 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Usp30 84749 Q70CQ3
Usp30 100756 Q3UN04
Usp30 304579  
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Top anti-Usp30 Antibodies at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-USP30 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$319.00
Details
Dog Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of USP30 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of USP30 expression in A549 (A), HeLa (B), THP1 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated IHC (p), WB Immunohistochemistry-Paraffin: USP30 Antibody - Staining of human testis shows moderate cytoplasmic immunoreactivity in seminiferous tubules cells. Western Blot: USP30 Antibody - Analysis in USP30 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells). 100 μL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa cells, using USP30 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB USP30 Antibody (N-term) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the USP30 antibody detected the USP30 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: USP30 Antibody - Analysis in control (vector only transfected HEK293T lysate) and uSP30 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells). Immunohistochemistry-Paraffin: USP30 Antibody - Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see Available
$181.73
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of extracts from HeLa cells, using USP30 antibody.The lane on the left is treated with the antigen-specific peptide. Western blot analysis of extracts from rat brain, using USP30 Antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB USP30 Antibody (N-term) (ABIN658703) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the USP30 antibody detected the USP30 protein (arrow). All lanes : Anti-USP30 Antibody (N-term) at 1:500 dilution Lane 1: Mouse pancreas lysate Lane 2: Mouse liver lysate Lane 3: Rat liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 59 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:500 400 μL Log in to see 10 to 11 Days
$385.00
Details

Top referenced anti-Usp30 Antibodies

  1. Human Polyclonal Usp30 Primary Antibody for IHC, IHC (p) - ABIN4364579 : Bingol, Tea, Phu, Reichelt, Bakalarski, Song, Foreman, Kirkpatrick, Sheng: The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy. in Nature 2014 (PubMed)

More Antibodies against Usp30 Interaction Partners

Human Ubiquitin Specific Peptidase 30 (Usp30) interaction partners

  1. the role of USP30 in the dynamic networks of mitochondrial quality control and its physiological implications.

  2. Here the authors report crystal structures of human USP30 bound to monoubiquitin and Lys6-linked diubiquitin, which explain how USP30 achieves Lys6-linkage preference through unique ubiquitin binding interfaces.

  3. show that USP30 delays mitophagy by delaying PARK2 recruitment to the mitochondria during mitophagy

  4. These results provide the first evidence for a fundamental role of USP30 in determining the threshold for mitochondrial cell death and suggest USP30 as a potential target for combinatorial anti-cancer therapy.

  5. The mechanism by which parkin, an E3 ubiquitin ligase, and USP30, a mitochondrion-localized deubiquitylase, regulate mitophagy, was investigated.

  6. reducing USP30 activity enhances mitochondrial degradation in neurons

  7. USP30 participates in the maintenance of mitochondrial morphology, a finding that provides new insight into the cellular function of deubiquitination.

Zebrafish Ubiquitin Specific Peptidase 30 (Usp30) interaction partners

  1. The distal ubiquitin-recognition mechanism of USP30 is similar to those of other USP family members, whereas Phe4 and Thr12 of the proximal ubiquitin are recognized by a USP30-specific surface.

Usp30 Antigen Profile

Protein Summary

USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008

Gene names and symbols associated with Usp30

  • ubiquitin specific peptidase 30 (USP30) antibody
  • ubiquitin specific peptidase 30 (usp30) antibody
  • ubiquitin specific peptidase 30 L homeolog (usp30.L) antibody
  • ubiquitin specific peptidase 30 (Usp30) antibody
  • 6330590F17Rik antibody
  • AI851327 antibody
  • D5Ertd483e antibody
  • si:dkey-72n1.2 antibody

Protein level used designations for Usp30

ubiquitin specific peptidase 30 , ubiquitin specific protease 30 , ubiquitin carboxyl-terminal hydrolase 30 , Ub-specific protease 30 , Ubiquitin thioesterase 30 , Deubiquitinating enzyme 30 , Ubiquitin-specific protease 30 , ubiquitin-specific-processing protease 30 , ubiquitin carboxyl-terminal hydrolase 30-like , deubiquitinating enzyme 30 , ub-specific protease 30 , ubiquitin thioesterase 30 , ubiquitin thiolesterase 30 , ubiquitin-specific protease 30

GENE ID SPECIES
416896 Gallus gallus
452215 Pan troglodytes
611662 Canis lupus familiaris
706607 Macaca mulatta
733894 Xenopus (Silurana) tropicalis
100049106 Xenopus laevis
100076803 Ornithorhynchus anatinus
100140210 Bos taurus
100153782 Sus scrofa
100231484 Taeniopygia guttata
100339118 Oryctolagus cuniculus
100392458 Callithrix jacchus
100473887 Ailuropoda melanoleuca
100538749 Meleagris gallopavo
100606082 Nomascus leucogenys
84749 Homo sapiens
100756 Mus musculus
304579 Rattus norvegicus
559099 Danio rerio
Selected quality suppliers for anti-Usp30 (Usp30) Antibodies
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